Navigation Links
New nanochemistry technique encases single molecules in microdroplets
Date:9/22/2009

Inventing a useful new tool for creating chemical reactions between single molecules, scientists at the National Institute of Standards and Technology (NIST) have employed microfluidicsthe manipulation of fluids at the microscopic scaleto make microdroplets that contain single molecules of interest. By combining this new microfluidic "droplet-on-demand" method with "optical tweezers" that could merge multiple droplets and cause their molecular contents to react, the research may ultimately lead to a compact, integrated setup for obtaining single-molecule information on the structure and function of important organic materials, such as proteins, enzymes, and DNA.

With the aid of NIST's Center for Nanoscale Science and Technology, physicists Carlos Lpez-Mariscal and Kristian Helmerson created a tiny microfluidic device with a channel through which water can flow. Squeezed into a narrow stream by a mixture of oils whose viscosity, or resistance to flow, exerts pressure on it, the water then enters a narrow constriction. The water's abrupt pressure dropaccompanied by a dash of detergentbreaks its surface tension, splitting it into small droplets. (This same effect occurs when a thin stream of water falling from a faucet breaks up into small drops.)

The droplet sizes are highly uniform and can be tuned by adjusting the width of the constriction. With this technique, the researchers made droplets about a micrometer in diameteror half an attoliter (half a billionth of a billionth of a liter) in volume.

In the microfluidic channel, the water is laced with desired molecules of just the right concentration, so that resulting droplets each pick up on average just one molecule of interest. Inside each droplet, the individual molecules of interest slosh around freely in the relatively roomy sphere, along with the water molecules that make up the bulk of every droplet.

By using laser beams, the researchers can move two or more single-mol
'/>"/>

Contact: Ben Stein
bstein@nist.gov
301-975-3097
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Breathing technique can reduce frequency, severity of asthma attacks
2. ORNL scientists hone technique to safeguard water supplies
3. Ben-Gurion U. developing new computer techniques to analyze historic Hebrew and Arabic documents
4. Scary ancient spiders revealed in 3-D models, thanks to new imaging technique
5. New advance in revolutionary bullet fingerprinting technique
6. New technique can fast-track better ionic liquids for biomass pre-treatments
7. New MRI technique could mean fewer breast biopsies in high-risk women
8. Can a new implant coating technique create a new six million dollar man?
9. Ovarian transplantation: First baby is born after a new technique
10. Ovarian transplantation: New technique gives greatly improved results in this delicate operation
11. Colon cancer screening technique shows continued promise in new study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New nanochemistry technique encases single molecules in microdroplets
(Date:3/24/2015)... PALM BEACH GARDENS, Fla. , March 24, ... of biometric identity management solutions, today announced that ... enabling premium clothing accessory retailer Goorin Bros ... login. The Crossmatch biometrics-based solution secures access to ... customers from the increased risk of data breaches. ...
(Date:3/23/2015)... 23, 2015  In the 2014 fiscal year, irs.gov ... losses. This figure accounts for a fraction of the ... Nilson Report, exceeds $11 billion globally. The polygraph has ... crime has occurred. Investor Mark Saint Juste ... Joe Paolella partnered to administer the test in ...
(Date:3/20/2015)... , Mar. 19, 2015 Research and Markets ... "Hand Geometry - Global Strategic Business Report" report ... markets for Hand Geometry in US$ Thousands. The report provides ... , Japan , Europe ... , and Rest of World. Annual estimates ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... Patients who have high blood sugar before undergoing ... clots, deep vein thrombosis and even pulmonary embolism ... of anesthesiology in the Artificial Pancreas Center at ... Philadelphia, and his colleagues examined records of nearly ...
... protect against some food allergies. Kefir, a traditional fermented drink, ... is often used to wean babies, as it is easily ... the age of three, with around 5-8% of infants at ... food. , "Friendly" bacteria in kefir may play a role ...
... in the event of a large-scale smallpox bioterrorist attack ... by researchers at Fred Hutchinson Cancer Research Center that ... , Instead, the current U.S. government policy of post-release ... workers and close contacts would be sufficient to thwart ...
Cached Biology News:Jefferson scientists find high glucose before surgery raises risk of dangerous complications 2Friendly bacteria in alcoholic milkshake could fight food allergies 2Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 2Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 3Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 4Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 5
(Date:4/21/2015)... , April 21, 2015 ... and development, custom automation, and contract manufacturing, and  ... accessible flow cytometry and cell sorting technology for ... develop a novel flow cytometry platform. ... NanoCellect Biomedical has developed a microchip-based cell sorting ...
(Date:4/21/2015)... 2015  Tute Genomics, a leading provider of cloud-based genomic ... as VP of Marketing. Mr. Forsythe is the latest ... in its commercial operations over the last two quarters. ... Forsythe is a tremendous addition to the Tute Genomics ... Tute Genomics. "Josh,s vast experience commercializing software technology in a ...
(Date:4/21/2015)... and RESEARCH TRIANGLE PARK, N.C. , ... UTHR ) announced today that it will release ... on Tuesday, April 28, 2015. United Therapeutics ... 2015, at 9:00 a.m. Eastern Time.  The teleconference is ... A rebroadcast of the teleconference will be available for ...
(Date:4/21/2015)... CA (PRWEB) April 21, 2015 Whether it’s ... a lab, or bolted to a Kessler CineDrive ... or at the beach, the TS3-H is designed to help ... on a brand-new state-of-the-art 5MP sensor, the TS5-H offers the ... with superior imaging characteristics. , According to Tom Boldt ...
Breaking Biology Technology:NanoCellect And Invetech Announce Collaboration To Develop Novel Flow Cytometry Platform For Cell Sorting And Analysis 2NanoCellect And Invetech Announce Collaboration To Develop Novel Flow Cytometry Platform For Cell Sorting And Analysis 3Tute Genomics Continues Expansion of Genomic Medicine Commercial Operations; Appoints Josh Forsythe as New VP of Marketing 2Tute Genomics Continues Expansion of Genomic Medicine Commercial Operations; Appoints Josh Forsythe as New VP of Marketing 3Tute Genomics Continues Expansion of Genomic Medicine Commercial Operations; Appoints Josh Forsythe as New VP of Marketing 4Fastec Imaging Releases the TS5-H High Definition High-Speed Camera 2Fastec Imaging Releases the TS5-H High Definition High-Speed Camera 3
... will potentially enable access to MRI exams for ... implantable cardiac ... Boston,Scientific Corporation (NYSE: BSX ) and Surgi-Vision, ... development arrangement for,magnetic resonance imaging (MRI)-safe technology. Physician implanters ...
... ... 2008, FT. MYERS, Fla., April 15 ... the,Securities and Exchange Commission its annual report on Form 10-KSB for the,year ended ... http://www.SEC.gov ., The audited financial statements for the year ended December ...
... April 15 Arpida Ltd.,(SWX: ARPN) today announced ... Thursday,17 April 2008 at 8.30am CET. In this ... need and developments in the area of anti-infective,drugs ... meeting of the Anti-Infective,Drugs Advisory Committee. During that ...
Cached Biology Technology:Boston Scientific and Surgi-Vision Announce Licensing Agreement for MRI-Safe Technology 2Boston Scientific and Surgi-Vision Announce Licensing Agreement for MRI-Safe Technology 3NeoGenomics Files Annual Report on Form 10-KSB with the SEC 2Arpida Announces Conference Call on 17 April 2Arpida Announces Conference Call on 17 April 3
Mouse monoclonal [7B9] to beta II Tubulin ( Abpromise for all tested applications). Antigen: Synthetic peptide, CEEEEGEDEA found at the c-terminus of beta II tubulin. Entrez GeneID: 10383 ...
Polymerase (RNA) II (DNA directed) polypeptide L...
...
...
Biology Products: