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New mouse collaborative cross resource promises new cures and treatments for diseases
Date:2/16/2012

may allow for more realistic assessments of the risk of adverse effects and may be a reliable route for applying findings from mouse to human populations."

Dr. David Threadgill (North Carolina State University and UNC Lineberger), who originally proposed the idea for this resource and is also a leader of the project, added, "Research on mouse models may lead to increased safety in human drug trials and consequently has the potential of reducing the costs of drug development."

"Publishing these papers in GSA's sister journals enables those interested in this research to access a large body of information quickly and easily," said Dr. Lauren McIntyre, senior editor of the journal GENETICS and professor in the Department of Molecular Genetics and Microbiology at the University of Florida. "The journals have made all the data associated with the papers openly available, and are committed to the widest possible distribution. This group of research articles should help accelerate the development of new treatments and drugs."

The international consortium developing these mouse populations includes the University of North Carolina (UNC), North Carolina State University (NCSU), The Jackson Laboratory, Tel Aviv University, Oxford University and Geniad/Australia. The mice are housed and 'curated' at UNC-Chapel Hill. The CC and DO populations are available for researchers worldwide who need a common genetic reference population for the integrative analysis of complex systems.


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Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-634-7302
Genetics Society of America
Source:Eurekalert

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