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New molecular insight into vertebrate brain development
Date:11/17/2008

Owing to the evolutionary conservation of the Hippo signaling pathway, Dr. Gage states that "understanding the HIPPO path may bring insights to human brain malformations. There are a number of brain size defects for which we are considering a follow up, including microcephaly and Autism, where the overall brain size is affected but structures retain the proportionality. The function of the HIPPO pathway also has implications for brain size evolution, which is of great interested to us."


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Contact: Heather Cosel
coselpie@cshl.edu
Cold Spring Harbor Laboratory
Source:Eurekalert

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