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New model synapse could shed light on disorders such as epilepsy and anxiety
Date:8/8/2012

at balance will affect the output of neural circuits." Chen added that, in the same analogy, the extrasynaptic regions could be thought of as the less-trafficked, but numerous smaller roads. "The idea is that if drugs could be developed that manipulate only the extrasynaptic receptors rather than the synaptic receptors, the 'major highways' would remain undisturbed and the heavy traffic could continue with less interruption. That is, targeting extrasynaptic receptors by modulating the Alpha 6 subunit represents a step toward creating new drugs with fewer side effects."


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Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State
Source:Eurekalert  

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New model synapse could shed light on disorders such as epilepsy and anxiety
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