Navigation Links
New microscopes at NIH reveal live, developing cells in unprecedented 3-D clarity
Date:10/25/2013

Researchers at NIH have developed two new microscopes, both the first of their kind. The first captures small, fast moving organisms at an unprecedented rate and the second displays large cell samples in three dimensions while decreasing the amount of harmful light exposure to the cells. Both microscopes surpass in clarity any other currently on the market.

The first microscope allows researchers to obtain fast moving images at double the spatial resolution of a conventional microscope. This provides a vastly clearer picture, enabling cell components that were once quite blurry to now become sharply defined; the difference is similar to that of a 1990's-era standard TV set versus today's high-definition TVs. The microscope is also 10 to 100 times faster than traditional technologies.

"It's always helpful to look at smaller and smaller things," said Hari Shroff, Ph.D., at NIH's National Institute of Biomedical Imaging and Bioengineering (NIBIB) lab chief of NIBIB's section on High Resolution Optical Imaging (HROI.) "Looking at a fixed cell at high resolution can tell you where different parts of the cell are at any given moment; but because much of biology depends on the movement of very small proteins finding each other and interacting, we really needed to look at how things move in a live cell."

The problem is that the higher the resolution, the harder it is to eliminate the blur from both light diffraction (the glow that sometimes occurs as light bends around objects) and the motion going on inside the live cell. Traditional linear structured illumination microscopy (SIM) cannot maintain the high resolution desired by researchers when the sample is moving quickly.

Shroff and his research fellow Andrew York, Ph.D., found an answer to these problems with their new instant linear structured illumination microscopy (iSIM), described in a paper published in Nature Methods on October 6th. Building on traditional SI
'/>"/>

Contact: Jessica Meade
nibibpress@mail.nih.gov
301-496-3500
NIH/National Institute of Biomedical Imaging & Bioengineering
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Research reveals first evidence of hunting by prehistoric Ohioans
2. Studies reveal structure of EV71, a virus causing childhood illnesses
3. Researchers reveal how a single gene mutation leads to uncontrolled obesity
4. Study reveals how monarch butterflies recolonize northern breeding range
5. Circadian rhythms have profound influence on metabolic output, UCI study reveals
6. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
7. Ancient civilizations reveal ways to manage fisheries for sustainability
8. Study by Haverford College professor reveals unprecedented impact of Deepwater Horizon on deep ocean
9. Nature: Video reveals wave character of particles
10. Plant research reveals new role for gene silencing protein
11. UGA scientists reveal genetic mutation depicted in van Goghs sunflower paintings
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New microscopes at NIH reveal live, developing cells in unprecedented 3-D clarity
(Date:7/2/2015)... Fingerprint Cards has received an order for its ... distributor World Peace Industrial Group (WPI), part of WPG Holdings. ... . Deliveries are planned to take place during Q3 ... manufacturers in Asia . The order value ... of approximately 2,200 MSEK for 2015. Jörgen Lantto, ...
(Date:6/30/2015)... June 30, 2015 Genisphere announced ... CEO to help further develop Genisphere,s therapeutics capabilities and ... experience, having spent much of the last 25 years ... Baxter Bioscience, and Johnson & Johnson. Tom started his ... and Biotech Corporate Finance. He graduated from Dartmouth College ...
(Date:6/26/2015)... ATL Technology, LLC, a top provider of electromechanical ... use solutions, headquartered in Springville, Utah , ... California corporation with locations in Santa ... Rica ). This acquisition will incorporate MedConx,s ... ATL Technology,s existing facility in Costa Rica ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2
... Polarstern has returned today to Bremerhaven from the Arctic ... ever both the Northeast and the Northwest Passages and ... the research vessel,s 23rd Arctic expedition, operated by the ... journey on August 12th in Reykjavik and ended it ...
... MADISON, WI, OCTOBER 20, 2008 -- The widespread use of ... decades, with little knowledge of the long-term effects on the ... study show that samples taken from over 300 wells across ... contamination. The news is a result of a decadal long ...
... LEDs may help ... Researchers in Germany are describing a potential alternative ... Their study, scheduled for the November 5 issue of ... journal, reports that high intensity visible light from light ...
Cached Biology News:Research around the North Pole 2Research around the North Pole 3Pesticide concentrations decreasing 2American Chemical Society Weekly PressPac Oct. 15, 2008 2American Chemical Society Weekly PressPac Oct. 15, 2008 3American Chemical Society Weekly PressPac Oct. 15, 2008 4American Chemical Society Weekly PressPac Oct. 15, 2008 5American Chemical Society Weekly PressPac Oct. 15, 2008 6American Chemical Society Weekly PressPac Oct. 15, 2008 7American Chemical Society Weekly PressPac Oct. 15, 2008 8
(Date:7/27/2015)... FRANKLIN, Tenn. , July 27, ... provider of health care services and one of ... today announced that its parent company and sole ... agreement with Medical Properties Trust, Inc. ("MPT") (NYSE: ... for $900 million in cash.  The transaction is expected to ...
(Date:7/27/2015)... ... July 27, 2015 , ... This is a professional and ... basic overview of the industry including definitions, classifications, applications and industry chain structure. ... competitive landscape analysis, and key regions development status. Development policies and plans are ...
(Date:7/27/2015)... ... July 27, 2015 , ... ... announced a new video: 3 Ways to GHS Labels . This video ... the Globally Harmonized System (GHS) by effectively labeling chemical containers. , “With the ...
(Date:7/27/2015)... -- Research presented at the 2015 AACC Annual Meeting ... that led to a fingerprick Ebola test becoming the ... receive approval from the World Health Organization (WHO). This ... West Africa by identifying suspected ... isolate and treat these patients much faster than is ...
Breaking Biology Technology:Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 2Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 3Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 4Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 52015 Biophotonics Market Global Research 22015 Biophotonics Market Global Research 3Brady Releases “3 Roads to GHS Labels” Video 2Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak 2Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak 3
... Boston Scientific,Corporation (NYSE: BSX ) today announced ... Drug Administration (FDA) to market its second-generation,TAXUS(R) Liberte(R) ... the TAXUS Liberte stent early next month in ... its TAXUS(R),Expresss2(TM) Atom(TM) Paclitaxel-Eluting Coronary Stent System, which ...
... Beike,Biotechnology Co. Ltd., ( http://www.beikebiotech.com ) ... through evidence-based medicine, announced,today it has signed eight ... the world,s most outstanding stem cell research organizations.,As ... a "Stem Cell Expert,Advisory Committee" and a separate ...
... WILMINGTON, Del., Oct. 10 AstraZeneca (NYSE:,AZN) today ... (FDA) has,approved once-daily SEROQUEL XR(R) (quetiapine fumarate) Extended-Release,Tablets ... associated with,bipolar disorder, the manic and mixed episodes ... of bipolar I disorder as adjunctive,therapy to lithium ...
Cached Biology Technology:Video: Boston Scientific Announces FDA Approval of Second-Generation TAXUS(R) Liberte(R) Drug-Eluting Stent 2Video: Boston Scientific Announces FDA Approval of Second-Generation TAXUS(R) Liberte(R) Drug-Eluting Stent 3Stem Cell Leader Beike Signs 8 New Cooperation Agreements, Establishes Safety Monitoring Boards 2Stem Cell Leader Beike Signs 8 New Cooperation Agreements, Establishes Safety Monitoring Boards 3FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 2FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 3FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 4FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 5FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 6FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 7FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 8FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania 9
ANTI END CEL LUNG AG...
EGTA, 50 g. Ethylene glycol-O,O-bis-[2-amino-ethyl]-N,N,N,N,-tetraacetic acid.Assay: > 99.0%. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Request Info...
RABBIT ANTI NEOPTERIN...
Biology Products: