Navigation Links
New microbial genetic system dissects biomass to biofuel conversion
Date:6/11/2010

MADISON A research team at the DOE Great Lakes Bioenergy Research Center (GLBRC) has developed a powerful new tool that promises to unlock the secrets of biomass degradation, a critical step in the development of cost-effective cellulosic biofuels. The details of this method were published online on June 11 in the journal Applied and Environmental Microbiology.

Fulfilling the promise of cellulosic biofuels requires developing efficient strategies to extract sugar molecules in biomass polymers like cellulose. Microorganisms such as bacteria and fungi are capable of converting biomass to simple sugars, but historically have been difficult to study using genetic approaches.

A breakthrough by a team of University of Wisconsin-Madison researchers at the GLBRC has made it possible to perform genetic analysis on Cellvibrio japonicus, a promising bacterium that has long been known to convert biomass to sugars. Using a technique called vector integration, the team has developed a method to generate a mutation in any gene within the organism.

As a test of the technique, the team constructed a mutation that inactivated a key component of a protein complex called a Type II Secretion System, and the disruption of this system prevented the bacterium from efficiently converting biomass into sugars. This proves for the first time that Cellvibrio uses the Type II Secretion System to secrete key enzymes for breakdown of biomass polymerase, thus providing key insight into how this bacterium obtains sugars from biomass.

"Realizing the promise of cellulosic biofuels requires identifying more efficient methods of releasing sugars from biomass", says GLBRC associate scientist David Keating, who led the team. "This new genetic method will allow us to understand how bacteria carry out this conversion, which should provide new avenues for improving the industrial process."

Plant cell wall deconstruction is a very complex process
'/>"/>

Contact: David Keating
dkeating@glbrc.wisc.edu
608-890-2547
University of Wisconsin-Madison
Source:Eurekalert

Page: 1 2

Related biology news :

1. DOE JGI produces new QC tool for microbial genomes
2. Microbial answer to plastic pollution?
3. New tool in the fight against mosquito-borne disease: A microbial mosquito net
4. UBC researchers find key microbial indicator of ocean health
5. Model microbial community for studying expanding dead zones characterized
6. TAXIS Pharmaceuticals licenses novel antimicrobial technology from Rutgers and UMDNJ
7. Reviews of microbial gene language published in special issue of Trends in Microbiology
8. Exploring standards to advance microbial genomics
9. MIT reels in RNA surprise with microbial ocean catch
10. Illinois Soil Nitrogen Test measures microbial nitrogen
11. Earths highest known microbial systems fueled by volcanic gases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/16/2014)... U.S. and beyond will convene in Lincoln, Nebraska, USA, ... existing science, and explore the unique geologic and historic ... applied geology, paleontology, and mid-continent geology. Events include a ... Kirk Johnson, Sant Director of the Smithsonian National Museum ... by the University of Nebraska-Lincoln. Lincoln is located near ...
(Date:4/16/2014)... Our ability to store memories improves during childhood, ... its connections with prefrontal and parietal cortices. New ... brain regions develop at this crucial time. Eventually, ... emerge in the transition into and during adolescence ... , Located deep in the middle of the ...
(Date:4/16/2014)... Martin Prechtl, Leo Heim and their colleagues at the ... new method of generating hydrogen using water and formaldehyde. ... interest when it comes to fuel cell technologies. The ... production using water and formaldehyde", have recently been published ... other applications, the new approach can be used to ...
Breaking Biology News(10 mins):Walking with mammoths and exploring mid-continental geology 2Walking with mammoths and exploring mid-continental geology 3Walking with mammoths and exploring mid-continental geology 4How kids' brain structures grow as memory develops 2
... the diaphragm muscles has received approval from the Food and ... Sclerosis (ALS), also known as Lou Gehrig,s disease. The ... patients breathe longer without the aid of a ventilator. ... Medical Center who helped develop and test DPS and who ...
... in the October 2011 print issue of The FASEB ... what kicks off the process that causes varicose veins. In ... binds to DNA to control gene function (called "transcription factor ... of proteins that significantly affect the development of varicose veins. ...
... work of a team of scientists at Cold Spring Harbor ... way to overcome one of the major technical obstacles preventing ... addressed successfully by novel drugs. The target is ... long known to be an important player in the signaling ...
Cached Biology News:Diaphragm pacing system receives FDA approval for use with ALS patients 2Scientists discover the proteins that control development of varicose veins 2Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity 2Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity 3Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity 4
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... ... initiative to create the next generation of fertilizers and production technologies, with initial financial ... ... -- IFDC is launching the Virtual Fertilizer Research Center (VFRC), a global ...
... , ... ... ... , ...
... ... ... ... ...
Cached Biology Technology:IFDC Launches Virtual Fertilizer Research Center 2IFDC Launches Virtual Fertilizer Research Center 3IFDC Launches Virtual Fertilizer Research Center 4IFDC Launches Virtual Fertilizer Research Center 5Icahn Nominates 4 to Genzyme Slate 2Icahn Nominates 4 to Genzyme Slate 3Icahn Nominates 4 to Genzyme Slate 4Icahn Nominates 4 to Genzyme Slate 5Icahn Nominates 4 to Genzyme Slate 6Icahn Nominates 4 to Genzyme Slate 7Icahn Nominates 4 to Genzyme Slate 8Icahn Nominates 4 to Genzyme Slate 9Icahn Nominates 4 to Genzyme Slate 10Longhorn Vaccines & Diagnostics LLC Receives FDA Emergency Use Authorization (EUA) for the First 2009 H1N1 Influenza Assay to Include a Molecular Transport Medium (MTM) 2Longhorn Vaccines & Diagnostics LLC Receives FDA Emergency Use Authorization (EUA) for the First 2009 H1N1 Influenza Assay to Include a Molecular Transport Medium (MTM) 3Longhorn Vaccines & Diagnostics LLC Receives FDA Emergency Use Authorization (EUA) for the First 2009 H1N1 Influenza Assay to Include a Molecular Transport Medium (MTM) 4Longhorn Vaccines & Diagnostics LLC Receives FDA Emergency Use Authorization (EUA) for the First 2009 H1N1 Influenza Assay to Include a Molecular Transport Medium (MTM) 5Longhorn Vaccines & Diagnostics LLC Receives FDA Emergency Use Authorization (EUA) for the First 2009 H1N1 Influenza Assay to Include a Molecular Transport Medium (MTM) 6
... Gene expression profiling allows a high-throuput screening ... naturally occuring or artifitially induced changes in ... that system can be detected, studied, classified ... broad range of genes at a glance. ...
... SYBR Green II RNA gel stain ... stain that has bright fluorescence when bound ... making it ideal for use with either ... or standard UV transilluminators. A 500 µL ...
Rabbit polyclonal to Esa1 ( Abpromise for all tested applications)....
... RNA gel stain is a sensitive nucleic ... bound to RNA and low background in gels, ... or polyacrylamide gels using laser scanners or standard ... 500 µL unit size (S-7564) and a special ...
Biology Products: