Navigation Links
New microbial genetic system dissects biomass to biofuel conversion
Date:6/11/2010

MADISON A research team at the DOE Great Lakes Bioenergy Research Center (GLBRC) has developed a powerful new tool that promises to unlock the secrets of biomass degradation, a critical step in the development of cost-effective cellulosic biofuels. The details of this method were published online on June 11 in the journal Applied and Environmental Microbiology.

Fulfilling the promise of cellulosic biofuels requires developing efficient strategies to extract sugar molecules in biomass polymers like cellulose. Microorganisms such as bacteria and fungi are capable of converting biomass to simple sugars, but historically have been difficult to study using genetic approaches.

A breakthrough by a team of University of Wisconsin-Madison researchers at the GLBRC has made it possible to perform genetic analysis on Cellvibrio japonicus, a promising bacterium that has long been known to convert biomass to sugars. Using a technique called vector integration, the team has developed a method to generate a mutation in any gene within the organism.

As a test of the technique, the team constructed a mutation that inactivated a key component of a protein complex called a Type II Secretion System, and the disruption of this system prevented the bacterium from efficiently converting biomass into sugars. This proves for the first time that Cellvibrio uses the Type II Secretion System to secrete key enzymes for breakdown of biomass polymerase, thus providing key insight into how this bacterium obtains sugars from biomass.

"Realizing the promise of cellulosic biofuels requires identifying more efficient methods of releasing sugars from biomass", says GLBRC associate scientist David Keating, who led the team. "This new genetic method will allow us to understand how bacteria carry out this conversion, which should provide new avenues for improving the industrial process."

Plant cell wall deconstruction is a very complex process
'/>"/>

Contact: David Keating
dkeating@glbrc.wisc.edu
608-890-2547
University of Wisconsin-Madison
Source:Eurekalert

Page: 1 2

Related biology news :

1. DOE JGI produces new QC tool for microbial genomes
2. Microbial answer to plastic pollution?
3. New tool in the fight against mosquito-borne disease: A microbial mosquito net
4. UBC researchers find key microbial indicator of ocean health
5. Model microbial community for studying expanding dead zones characterized
6. TAXIS Pharmaceuticals licenses novel antimicrobial technology from Rutgers and UMDNJ
7. Reviews of microbial gene language published in special issue of Trends in Microbiology
8. Exploring standards to advance microbial genomics
9. MIT reels in RNA surprise with microbial ocean catch
10. Illinois Soil Nitrogen Test measures microbial nitrogen
11. Earths highest known microbial systems fueled by volcanic gases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... VIEW, Calif. , July 30, 2015 /PRNewswire/ ... and services for gene function analysis and biomarker ... Guide RNA (sgRNA) Knockout Library targeting all human ... specifically and permanently "knock out" a gene,s function. ... provides a high throughput screening tool so that ...
(Date:7/21/2015)... , July 21, 2015 Today, ZTE ... Already received as well as expected revenues in 2015 that relate ... FPC,s communicated revenue guidance of approximately 2,200 MSEK for 2015. ... is a leading smartphone manufacturer in China ... FPC1 02 5 for Axon , ...
(Date:7/13/2015)... , Jul. 13, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile ... provisional patent 62/188684 for BEHAVIORAL-DIRECTED AUTHENTIATION ... new convenient and secure method to make payments.  ... payment methods, introduced with its groundbreaking voice-direct payment ...
Breaking Biology News(10 mins):CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2FPC's Touch Fingerprint Sensor FPC1025 in ZTE's Smartphone Axon 2NXT-ID Patents Behavior-Directed Payments 2NXT-ID Patents Behavior-Directed Payments 3NXT-ID Patents Behavior-Directed Payments 4
... a climate as prone to extremes as Canada,s, buildings ... innovative solutions are being explored through the NSERC Smart ... initiative headquartered at Concordia, which has just received $1 ... "Through the ecoENERGY Innovation Initiative, our Government ...
... MNMay 2, 2013UnitedHealth Group and the Minneapolis Heart Institute ... of New Ulm, Minn., recently announced two grants from ... will fund weight management and nutrition initiatives for Hearts ... a research and demonstration project with a goal of ...
... to announce the launch of Environmental Science & ... accelerate the pace of research across the environmental field ... leading publishing outlet to highlight urgent critical findings in ... release its first issue January 2014 and open for ...
Cached Biology News:$1 million for smart energy solutions 2UnitedHealth Group grants more than $1 million for the heart of New Ulm project 2New ACS journal Environmental Science and Technology Letters to rapidly publish urgent research 2New ACS journal Environmental Science and Technology Letters to rapidly publish urgent research 3
(Date:8/3/2015)... 2015 E-QURE Corp. (OTCQB: EQUR), ... Bio-electrical Signal Therapy device ("BST Device"), a new and ... heal chronic wounds, today announced that the Company has ... distributor specializing in medical devices, for the marketing and ... a 70 years old, sales, marketing and distribution company ...
(Date:8/3/2015)... NEW YORK , August 3, 2015 ... "Global Market Study on 3D Cell Culture: ... published by Persistence Market Research, the global 3D cell culture ... is expected to expand at a CAGR of 29.1% ... View Full Report with TOC:  http://www.persistencemarketresearch.com/market-research/3d-cell-cultures-market.asp ...
(Date:8/3/2015)... ... 2015 , ... Sterlitech Corporation introduces the compact, quiet, and ... laboratory equipment. With optimized features, such as PTFE-coated contact surfaces, an oil-free design, ... solution for a broad range of vacuum filtration applications. , Featuring a 1/7 ...
(Date:7/31/2015)... ... July 31, 2015 , ... Global ... and premium industry insights on the global resorcinol industry. The report highlights the ... of vivid market scenarios and analysis of primary and secondary inputs from the ...
Breaking Biology Technology:E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4Sterlitech Launches New Line of Vacuum Pumps 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4
... Area Economic Development Corporation 's annual business-plan contest is starting ... the best business ideas from Eau Claire County. , ,For ... on March 29. Then entrants in the Creating Your ... prepare their applications. , ,Businesses judged to have the best ...
... Metavante Corporation has completed its acquisition of ... says it is expanding its Healthcare Payments Solutions ... Reynolds, who previously served as senior vice president ... Wells Fargo Institutional Trust Service, will become president ...
... , a local software and consulting firm, has teamed ... a new geographic information systems application, the companies said ... to create and distribute land records data through a ... challenges faced by organizations trying to maintain and distribute ...
Cached Biology Technology:
... ULS cDNA Synthesis and Labeling Kit generates ... experiments. First unmodified cDNA is made via ... using an Oligo(dT) primer. Unlike other methods, ... in the reverse transcription reaction. This unmodified ...
... enables fully automated hybridization of microarrays on ... been designed to offer researchers improved reproducibility, ... perform a wide range of applications. ... 485C; denaturations of up to 99C. The ...
... The user-friendly Eppendorf Thermomixer R offers ... that require shaking, heating, and cooling. ... expanded its application and temperature control ... each accommodate 24 micro test tubes, ...
... a high quality microarray scanner based on patented ... and spatial resolution. The DNAscope LM is ... microarray scanner that is upgradeable to a total ... Includes control module (computer), monitor, ...
Biology Products: