Navigation Links
New methods to identify MRSA in pigs

Traditionally, MRSA has been associated with severe infections which occur in hospitals and result in prolonged diseases and increased mortality. However, in recent years, MRSA has spread to the rest of the community, e.g. MRSA CC398 is found in pig production.

MRSA is resistant to the antibiotics with which we normally use for treatment of Staphylococcus infections.

In her PhD project at the National Food Institute, PhD student Mette Theilgaard exploited the latest technologies within whole genome sequencing and studied the entire DNA of MRSA CC398.

These studies have resulted in new methods, high-throughput approaches, which can identify genes important for the survival of MRSA in pigs. High-throughput approaches can identify those genes in the total gene pool of the bacteria which are essential, or the presence of which is advantageous, for the bacteria under some given circumstances.

Transfer of Disease From Animals To Humans

The fact that MRSA can spread from animals to humans, where they may result in infections, has caused great concern in recent years. LA-MRSA ST398 is a new type and has turned out to be particularly successful in colonisation of pigs, from where it may transmit to humans.

Therefore, several monitoring studies focus on locating the origin of this MRSA type and its potential. Several central questions still remain unanswered, which makes it difficult to control the spread of this MRSA type. LA-MRSA ST398 is zoonotic, i.e. it can be transferred directly from animals to humans and cause disease. Thus, it is not sufficient to eradicate the bacteria from humans.

LA-MRSA ST398 has proven to be particularly successful in colonisation of pigs. By studying which genes are essential for the bacteria in pigs it may be possible for researchers to identify the factors important for the bacterium to colonise on pigs. We still don't know which specific genetic factors in this MRSA type facilitate the spread from animals to humans.


Contact: Frank Muller Aarestrup
Technical University of Denmark

Related biology news :

1. Study of bigeye tuna in Northwest Atlantic uses new tracking methods
2. Novel methods may help stem cells survive transplantation into damaged tissues
3. Comparison study of planting methods shows drilling favorable for organic farming
4. Animal testing methods for endocrine disruptors should change, team argues
5. Frederic Bushman, Ph.D. receives Pioneer Award for advancing therapeutic gene delivery methods
6. Fungal infection control methods for lucky bamboo
7. Developing methods for building precise nanostructures
8. Updating air pollution measurement methods with air quality, health effects research
9. New methods improve quagga and zebra mussel identification
10. New methods to visualize bacterial cell-to-cell communication
11. Research examines new methods for managing digestive health
Post Your Comments:
(Date:11/10/2015)... , Nov. 10, 2015  In this ... the basis of product, type, application, disease ... in this report are consumables, services, software. ... are safety biomarkers, efficacy biomarkers, and validation ... report are diagnostics development, drug discovery and ...
(Date:11/4/2015)... , November 4, 2015 ... new market report published by Transparency Market Research "Home Security ... Trends and Forecast 2015 - 2022", the global home security ... 30.3 bn by 2022. The market is estimated to ... period from 2015 to 2022. Rising security needs among ...
(Date:10/29/2015)... -- Daon, a global leader in mobile biometric authentication ... version of its IdentityX Platform , IdentityX v4.0. ... have already installed IdentityX v4.0 and are seeing ... UAF certified server component as an option and ... These customers include some of the largest and most ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... Florida , November 30, 2015 ... specializing in the development of innovative peptide and gene-based ... metastatic disease, today announced it will be presenting at ... on December 1, 2015 at 2.30 PM PT. Dr. ... and Strategic Advisor will be giving the presentation and ...
(Date:11/30/2015)... 2015  Aytu BioScience, Inc. (OTCQB: AYTU), a commercial-stage ... will present at two upcoming investor conferences. Aytu is ... virtual conference, to be held December 3, 2015, and ... held December 2 nd & 3 rd , ... streamed live via webcast. Josh Disbrow , ...
(Date:11/30/2015)... RATON, Florida and MAGDEBURG, Germany ... Congress of NeuroRehabilitation (ECNR) in Vienna, Austria ... 3rd European Congress of NeuroRehabilitation (ECNR) in ... 2015. --> NovaVision, a wholly owned subsidiary of ... the European version of its Internet-delivered NovaVision Therapy Suite at ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... integration with MarkLogic, the Enterprise NoSQL database platform provider, creating a seamless ... , Smartlogic’s Content Intelligence capabilities provide a robust set of semantic tools ...
Breaking Biology Technology: