Navigation Links
New methods, new math speed detection of drug-resistant malaria
Date:8/2/2010

Researchers at Case Western Reserve University developed techniques to quickly identify evolution of drug resistance in strains of malaria. Their goal is to enable the medical community to react quickly to inevitable resistance and thereby save lives while increasing the lifespan of drugs used against the disease.

Currently, disease monitoring requires months of clinical trials. The new methods can provide more information in just days, and far cheaper.

The investigators have tailored genetic assays and mathematical analysis to uncover and track drug immunity of the deadliest form of the disease, caused by the parasite Plasmodium falciparum. But, the technology could be used for other forms of malaria and other diseases.

The investigators report their work in the online journal BioMed Central Genetics. The link: http://www.biomedcentral.com/1471-2156/11/57.

"Each year an estimated 1 million to 2.5 million children die as a direct result of malaria; a conservative estimate is that one child dies of malaria every 30 seconds," said Peter Zimmerman, a professor of international health at Case Western Reserve School of Medicine. "More accurate surveillance of drug resistance in malaria parasite populations will reduce the number of deaths."

Earlier detection of resistance enables health care workers to adjust treatments sooner, ideally before resistance becomes fully established in a population and eliminates a drug from use, he explained.

"There is no vaccine for malarial parasites; we depend on drugs and the biggest threat is the parasites continue to evolve resistance," said Carol Hopkins Sibley, a professor of genome sciences at the University of Washington and scientific director of the WorldWide Antimalarial Resistance Network. She was not involved in the research.

"They've come up with a better way to identify resistance," H
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Mays Cold Spring Harbor Protocols features plant gene expression methods, Xenopus imaging
2. Biologists merge methods, results from different disciplines to find new meaning in old data
3. Protein analysis methods, viral vectors featured in Cold Spring Harbor Protocols
4. Scientists post lower speed limit for cell-signaling protein assembly
5. Sensing wind speed with kites
6. The brain of the fly -- a high-speed computer
7. For speediest athletes, its all in the center of gravity
8. The search for improved carbon sponges picks up speed
9. Discovery: Yeast make plant hormone that speeds infection
10. Organic solids in soil may speed up bacterial breathing
11. Chemist stitches up speedier chemical reactions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... 2013 Joshua Obar, Ph.D., Department of Immunology and ... a 2013 ICAAC Young Investigator Award for his research ... responses to infection. , Obar earned his B.A. ... went on to complete his Ph.D. in Microbiology and ... his Ph.D. thesis research in Edward Usherwood,s laboratory at ...
(Date:6/18/2013)... Methylation refers to a chemical modification of DNA ... positions in the DNA sequence. Until now, scientists ... expression of certain genes. Today, a team of ... led by Emmanouil Dermitzakis, Louis-Jeantet Professor at the ... always the case and that DNA methylation may ...
(Date:6/17/2013)... other locations with central nervous system infections may well ... virus, according to a study to be published in ... American Society for Microbiology. Researchers have detected the virus ... with central nervous system infections of unknown cause, and ... from pigs and poultry, suggesting animals may serve as ...
Breaking Biology News(10 mins):The American Society for Microbiology honors Joshua Obar 2The secret of DNA methylation 2New virus discovered in patients with central nervous system infections 2New virus discovered in patients with central nervous system infections 3
... 2011 The American Chemical Society (ACS) today released ... Solutions " podcast series showcasing a discovery that ... a key ingredient used to make everything from paint ... focus on a new way to make acrylic acid, ...
... in German . , Trichomes, hair-like projections ... herbivores: they can be obstacles, traps, or reservoirs for ... attenuata contain primarily acyl sugars, which are composed ... aliphatic acids, compounds that give baby vomit its distinctive ...
... around the world have forced many species to the brink ... multiple causes that are still not fully understood, researchers conclude ... causative factor is often missing the larger picture, they said, ... don,t consider the totality of causes or could even ...
Cached Biology News:Lollipops with side effects 2Lollipops with side effects 3Lollipops with side effects 4Catastrophic amphibian declines have multiple causes, no simple solution 2Catastrophic amphibian declines have multiple causes, no simple solution 3
(Date:6/18/2013)... KONG, June 18, 2013 China Cord Blood ... "Company"), China,s leading provider of cord blood collection, laboratory ... services, today announced its preliminary unaudited financial results for ... 2013 ended March 31, 2013. Fourth ... the fourth quarter of fiscal 2013 increased by 33.3% ...
(Date:6/18/2013)... Rockville, MD, USA (PRWEB) June 18, 2013 ... today announced the opening of two new offices in ... office in Singapore will serve as RAPS’ Pan-Asia ... Shanghai office will be more focused on audiences within ... after RAPS announced its partnership with five Singapore government ...
(Date:6/18/2013)... June 18, 2013 DuPont welcomes 48 ... 11th annual DuPont National AgriScience Teachers Ambassador Academy this ... in Chestertown, Md. , The NATAA “Ag ... and is a special project of the National ... Agricultural Educators (NAAE) . The highly recommended agriscience ...
(Date:6/18/2013)... , June 18, 2013 ... release of the HELM biomolecular representation standard software ... MIT licence. HELM (Hierarchical Editing Language ... range of biomolecules (e.g. proteins, nucleotides, antibody drug ... and sequence-based informatics methodologies impractical or unusable. HELM ...
Breaking Biology Technology:China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 2China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 3China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 4China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 5China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 6China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 7China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 8China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 9China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 10China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 11China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 12China Cord Blood Corporation Reports Financial Results for the Fourth Quarter and Full Year of Fiscal 2013 13RAPS Opens Offices in Singapore and China 2RAPS Opens Offices in Singapore and China 3DuPont Sponsors National AgriScience Ambassador Academy 2DuPont Sponsors National AgriScience Ambassador Academy 3The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools 2
... Ontario, April 30, 2012  IGY Immune Technology & ... its proprietary IgY products.  IgY from chicken egg ... its immune enhancing benefits in humans as well ... fight sickness and maintain good health.  Until now, ...
... Therapeutics Inc ., a biopharmaceutical company leading the discovery ... the appointment of Bruce Carter, Ph.D. to its Board ... member of the Board of Directors of Immune Design ... and as a board member of additional scientific organizations. ...
... Lawrence Berkeley National Laboratory (Berkeley Lab) and the ... first self-assembly of nanoparticles into device-ready materials. Through ... blending nanoparticles with block co-polymer supramolecules, the researchers ... one-, two- and three-dimensional arrays of gold nanoparticles. ...
Cached Biology Technology:IGY Immune Technology & Life Sciences Purchases Manufacturing Facility to Produce Purified Immunoglobulin Y (IgY) 2Regulus Therapeutics Appoints Bruce Carter to its Board of Directors 2Regulus Therapeutics Appoints Bruce Carter to its Board of Directors 3Regulus Therapeutics Appoints Bruce Carter to its Board of Directors 4Golden potential for gold thin films 2Golden potential for gold thin films 3
Formulation: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide....
... 100 Instrument System is ideal for ... Upstate's Beadlyte reagents. The Luminex 100 ... with software version 1.7, the XY ... Upstate offers $2000 in free Beadlyte ...
normal human fibroblasts Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Purified anti-Fanconi anemia D2-Phosphorylated (Ser222)...
Biology Products: