Navigation Links
New method yields potent, renewable human stem cells with promising therapeutic properties
Date:3/25/2014

New Rochelle, NY, March 24, 2014The curative and therapeutic potential of mesenchymal stem cells (MSCs) offers much promise, as these multipotent cells are currently being tested in more than 300 clinical trials in a range of diseases. A new, easier, and more reliable way to make large quantities of highly potent MSCs could accelerate progress toward their use in regenerative medicine, as described in an article in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Stem Cells and Development website.

Robert Lanza, MD and colleagues from Advanced Cell Technology (Marlborough, MA) and the David Geffen School of Medicine, UCLA (Los Angeles, CA), developed an innovative method for deriving MSCs from human embryonic stem cells (hESCs) through the use of a developmental precursor called the hemangioblast. They describe the technique and evidence of therapeutic efficacy using the hESC-MSCs to treat mouse models of lupus erythematosus and uveitis in the article "Mesenchymal Stem Cell Population Derived from Human Pluripotent Stem Cells Displays Potent Immunomodulatory and Therapeutic Properties."

"This new population of hESC-derived MSCs has a 30,000-fold greater proliferative capacity than bone marrow-derived MSCs," says Dr. Lanza, Chief Scientific Officer, Advanced Cell Technology. "In addition to being easy to derive in very large numbers, they are more youthful and live much longer." Dr. Lanza is Editor-in-Chief of BioResearch Open Access, a peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers that provides a rapid-publication forum for a broad range of scientific topics.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. A non-invasive, rapid screening method for Alzheimers disease
2. AZTI-Tecnalia develops a methodology for authenticating canned tuna species within 24 hours
3. Researchers warn against abrupt stop to geoengineering method
4. New NIST method evaluates response to oxidation in live cells
5. Caltech-developed method for delivering HIV-fighting antibodies proven even more promising
6. New method developed for ranking disease-causal mutations within whole genome sequences
7. GW receives up to $14.6 million to develop method to characterize security threats
8. New method increases supply of embryonic stem cells
9. Gold nanoparticles help to develop a new method for tracking viruses
10. Developing methods for building precise nanostructures
11. Big data: A method for obtaining large, phylogenomic data sets
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New method yields potent, renewable human stem cells with promising therapeutic properties
(Date:1/28/2016)... Calif., Jan. 28, 2016 Synaptics (NASDAQ: SYNA ), ... for its second quarter ended December 31, 2015. ... quarter of fiscal 2016 increased 2 percent compared to the comparable ... quarter of fiscal 2016 was $35.0 million, or $0.93 per diluted ... net income for the first quarter of fiscal 2016 grew 9 ...
(Date:1/22/2016)... DUBLIN , Jan. 22, 2016 /PRNewswire/ ... announced the addition of the "Global ... report to their offering. --> ... of the "Global Biometrics Market in ... offering. --> Research and ...
(Date:1/18/2016)... Calif. , Jan. 18, 2016  Extenua ... software that simplifies the use and access of ... and go-to-market partnership with American Cyber.  ... brings extensive experience leading transformational C4ISR and Cyber ... and integrating the latest proven technology solutions," said ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... , Feb. 11, 2016  Bioethics International, a not-for-profit ... are researched, developed, marketed and made accessible to patients around ... Open had named the publication of the Good ... The publication is also featured as one of BMJ ... the last year that are most frequently read. ...
(Date:2/11/2016)... , Feb. 11, 2016  Wellcentive today announced ... Portland, Oregon -based community care organization ... population health analytics, quality reporting and care management ... strengthen its team of quality managers, analysts and ... the provider groups serving FamilyCare members. ...
(Date:2/11/2016)... CRUZ, Calif. , Feb. 11, 2016  Dovetail ... applications to its beta program for a planned metagenomic ... will present the company,s metagenomic genome assembly method in ... Advances in Genome Biology & Technology conference in ... assembly of these highly complex datasets is difficult. Using ...
(Date:2/11/2016)... BioInformant announces the February 2016 release of its ... and Technologies – Market Size, Segments, Trends, and Projections ... The first and only market research firm ... more than a decade of historical information on all ... type. This powerful 175 page global strategic report contains ...
Breaking Biology Technology: