Navigation Links
New method separates cancer cells from normal cells
Date:6/15/2009

ive and cell-repellant chemical compounds onto a substrate. The cells stayed out of the repellant areas and localized onto the "ratchet" channels, which then directed the cells' movements.

Grzybowski and his colleagues took this knowledge one critical step farther: they designed channels that successfully moved the cells of two types -- notably, cancerous and non-cancerous -- in opposite directions and thus partly sorted them out.

To sort the cells, they took advantage of the cells' different shapes and mobility characteristics. Migrating cancer cells tend to be more round and broad while normal, epithelial cells are long and thin with long protrusions on the ends. The researchers designed a channel with "spikes" coming out at 45-degree angles from the walls, alternating on opposite sides of the channel. This pattern funnels cancer cells in one direction while at the same time directing the normal cells in the opposite direction, as those cells "grab" the spikes and pull themselves through.

The researchers showed that a device with a number of these channels leading to a central reservoir, like spokes on a wheel, worked just as well separating cancer and non-cancerous cells. A stack of these radially arranged ratchet channels could be used to create a "cancer trap."

"When implanted next to a tumor the particles would guide cancer cells, but not normal cells, inward to the reservoir, where they would be trapped," said Grzybowski. "The particles could also be part of the sutures used during surgical procedures."


'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

1

GOOD

Page: 1 2

Related biology news :

1. K-State host to workshop on rapid methods to detect microorganisms in food
2. Scholar unconvinced new lie-detection methods better than old ones
3. Protein analysis methods, viral vectors featured in Cold Spring Harbor Protocols
4. New method developed by UC San Diego bioengineers gives regenerative medicine a boost
5. Cold and brown fat raise the prospect of a new method of treating obesity
6. New method for detection of phosphoproteins reveals regulator of melanoma invasion
7. Scientists develop method for comprehensive proteome analysis
8. Engineers develop method to disperse chemically modified graphene in organic solvents
9. Pilot study shows effectiveness of new, low-cost method for monitoring hand hygiene compliance
10. New method for detecting explosives
11. Genomatix gets patent for comparative genomics method
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2009)... American researchers found the fossil remains of a whale, 4.5 ... for the first time, the results of the decay and ... cetacean, possibly a baleen whale from the Mysticeti group. , ... remains of a whale from the Lower Pliocene (five million ... is the first time that the results of the processes ...
(Date:12/15/2009)... near future, consumers can look forward to ultra-low ... laptops, PDAs and mobile phones. This is made ... technologies which are critical elements for power optimisation ... systems. , Analog IC design is the key ... To pre-position the nation in advanced analog and ...
(Date:12/15/2009)... laboratory model organism, but there are currently few ... and blood-forming tissues in this species. A ... resources from Cold Spring Harbor Laboratory Press fills ... step-by-step protocols for the preparation, enumeration, and microscopic ... hematopoietic tissues in the mouse. The laboratory ...
Breaking Biology News(10 mins):Story of 4.5 million-year-old whale unveiled in Huelva 2Story of 4.5 million-year-old whale unveiled in Huelva 3NTU and EDB launch S$50 million ($36 million) integrated circuit design research center 2NTU and EDB launch S$50 million ($36 million) integrated circuit design research center 3New source of classical techniques for blood-based studies in the laboratory mouse 2New study finds links between video game playing and health risks in adults 54699 1New study finds links between video game playing and health risks in adults 54699 2New study finds links between video game playing and health risks in adults 54699 3Phylicia Rashad Reaches Weight Loss Goal 3B Loses 35 lbs 54698 1Phylicia Rashad Reaches Weight Loss Goal 3B Loses 35 lbs 54698 2UCI chemistry center awarded 2420 million from NSF 13599 1UCI chemistry center awarded 2420 million from NSF 13599 2
... not only smart, but they also wage a good ... studies have shown that plants can sense attacks by ... been known what happens between the pathogen attacks and ... revealed a very complex process that explains how plants ...
... on faculty in the Virginia-Maryland Regional College of ... been awarded funding from the Wake Forest University ... treating brain tumors in dogs, cats and humans. ... the Department of Small Animal Clinical Sciences (DSACS), ...
... part of the answer to saving the Earth from ... , A team from Newcastle University aims to design ... and cost-effectively. This has never previously been attempted anywhere ... the Engineering and Physical Sciences Research Council. , ...
Other Biology News:Researcher discovers pathway plants use to fight back against pathogens 2Veterinary college researcher studying brain tumors in people and animals 2Veterinary college researcher studying brain tumors in people and animals 3Specially-designed soils could help combat climate change 2
(Date:12/16/2009)... pacemakers may inadequately stimulate a patient,s heart while ... to the magnetic pulses mixing with the electronic ... is potentially dangerous for the patient undergoing the ... Central,s open access journal BioMedical Engineering Online ... uses a magnetic field instead of ionizing radiation ...
(Date:12/16/2009)... among the Best in the Nation ,, ... proudly announces it has been granted Magnet(R) recognition ... Recognition Program(R). Magnet(R) is one of the highest ... can achieve, and places Hahnemann among the five ... achieved this prestigious distinction. ,, At 9:00 am ...
(Date:12/16/2009)... 22% for fiscal 2009; on track for positive ... 16 /PRNewswire-FirstCall/ - Microbix Biosystems Inc. (MBX:TSX) a ... today reported financial results for fourth quarter and ... 30, 2009, Microbix reported revenues of $6.08 million, ... 2008. For fourth-quarter 2009, the Company saw revenues ...
(Date:12/16/2009)... BioSciences, LLC introduces HSP-A Soy Peptone. HSP A has been ... , ... (PRWEB) December 16, 2009 -- Nu-Tek BioSciences, LLC. ... introducing HSP-A Soy Peptone. HSP-A, previously manufactured by Nutricepts, Inc. ... proven to improve growth rates and yields. HSP-A has been ...
Breaking Biology Technology:FDA researchers identify new MRI safety risk for patients with pacemakers 2Hahnemann University Hospital Granted Magnet(R) Status 2Hahnemann University Hospital Granted Magnet(R) Status 3Microbix' Pipeline Set To Reach Milestones In 2010 2Microbix' Pipeline Set To Reach Milestones In 2010 3Microbix' Pipeline Set To Reach Milestones In 2010 4Microbix' Pipeline Set To Reach Milestones In 2010 5Microbix' Pipeline Set To Reach Milestones In 2010 6Microbix' Pipeline Set To Reach Milestones In 2010 7Microbix' Pipeline Set To Reach Milestones In 2010 8
... Imaging,Diagnostic Systems, Inc., (OTC Bulletin Board: IMDS) a ... today that its,distributor, Laszlo Meszaros of Kardia Hungary ... system for Budapest, Hungary., (Logo: http://www.newscom.com/cgi-bin/prnh/20040412/IMDSLOGO ... installed at the new MeDoc HealthCare Center,(MDHC) located ...
... Australia through ... retail pharmacies nationwide, TAMPA, Fla., Oct. ... in pharmacy-based patient care services and,healthlinks.net, a subsidiary of the ... definitive technology licensing and business,consulting agreement, paving the way for ...
... teams selected to receive funding for preclinical and clinical ... ... disorders, ROCKLAND, Mass., Oct. 14 The Michael J. ... million to five,research teams to speed development of effective therapies ...
Other Biology Technology:Imaging Diagnostic Systems Sells Its CT Laser Mammography System to Budapest, Hungary 2Mirixa Announces Agreement With the Pharmacy Guild of Australia 2Mirixa Announces Agreement With the Pharmacy Guild of Australia 3Michael J. Fox Foundation Awards $2 Million Grant From EMD Serono to Research Projects on Cognitive Deficits in Parkinson's Disease 2Michael J. Fox Foundation Awards $2 Million Grant From EMD Serono to Research Projects on Cognitive Deficits in Parkinson's Disease 3Michael J. Fox Foundation Awards $2 Million Grant From EMD Serono to Research Projects on Cognitive Deficits in Parkinson's Disease 4Michael J. Fox Foundation Awards $2 Million Grant From EMD Serono to Research Projects on Cognitive Deficits in Parkinson's Disease 5
Mouse monoclonal antibody raised against a partial recombinant EOMES. NCBI Entrez Gene ID = EOMES...
... antibody raised against a partial ... Immunogen: SLC22A3 (NP_068812, 90 ... recombinant protein with GST tag. ... NM_021977 ...
Mouse monoclonal antibody raised against a partial recombinant AAAS. NCBI Entrez Gene ID = AAAS...
Mouse monoclonal antibody raised against a partial recombinant PUM2. NCBI Entrez Gene ID = PUM2...
Biology Products: