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New method isolates immune cells for researchers to study how they ward off oral diseases
Date:4/15/2014

phocytes that play a role in fighting oral diseases. The cells are part of the adaptive immune system in which cells respond to pathogens invading the body.

The researchers took tissue samples from the mouths of mice and washed them several times in saline and chemical solutions with antibiotics. This was followed by disintegrating the tissue using salts and enzymes. The solution was centrifuged and strained to separate different tissue parts with more washings and separations before the cells could be studied and grown.

Pandiyan, who received an early career travel award from the American Association of Immunologists (AAI) will present her findings at the organization's annual meeting, May 2-7, in Pittsburgh.

Natarajan Bhaskaran, Yifan Zhang and Aaron Weinberg, from Case Western Reserve University's Department of Biological Sciences, contributed to the study, which was funded by the university's dental school.


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Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

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