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New method generates cardiac muscle patches from stem cells
Date:6/19/2012

f the cells.

"Action potential and calcium wave impulse propogation trigger each normal heart beat, so it is imperative to record each parameter in bioengineered human cardiac patches," Herron says.

Authors of the study note that the velocity of the engineered cardiac cells, while faster than previous reports, it is still slower than the velocity observed in the beating adult heart.

Still the velocity is comparable to commonly used rodent cells, and authors suggest human cardiac patches could be used rather than rodent systems for research purposes.

The new method can be readily applied in most cardiac research laboratories and opens the door for the use of cardiac stem cell patches in disease research, testing of new drug treatments and therapies to repair damaged heart muscle.
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Contact: Shantell M. Kirkendoll
smkirk@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

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