Navigation Links
New method for safer dosing of anticoagulants
Date:12/6/2011

Elderly people with atrial fibrillation are often treated with anticoagulants to thin the blood, but this medicine is hard to dose and patients have to have their blood tested regularly. Researchers at the Sahlgrenska Academy at the University of Gothenburg and Chalmers University of Technology have now devised a new method that improves the accuracy of risk assessments.

Atrial fibrillation, or irregular heartbeat, is a very common heart rhythm disturbance that increases the risk of stroke and death. It is usually treated with warfarin, where the dose is calculated by measuring the coagulation of the blood. The dose is increased if coagulation is too quick, and decreased if it is too slow. Patients with unsatisfactory samples are tested more frequently, while satisfactory samples mean that the test interval can be extended.

New measurement method more reliable

In a study involving 20,000 patients in Sweden, Marcus Lind, postdoctoral researcher at the University of Gothenburg's Sahlgrenska Academy and consultant at the NU group of hospitals, tested a new measurement method that assesses far more reliably who is at risk of serious complications and admission to hospital.

"Our method takes account of how blood viscosity goes up and down," says Lind. "This meant that we could establish far more reliably which patients were at risk of a stroke, haemorrhaging or dying."

Collaboration with Chalmers

The new method also takes account of the values' extremes. "In the past we've only checked whether patients fall within the therapeutic range but the new method allows us to identify more accurately how coagulation varies both within and beyond this range," says Anders Odn, professor of biostatistics at Chalmers University of Technology, who played a key role in developing the new method.

Reduces risks

The new method improves the chances of understanding which patients are at risk of complications, and is therefore an indicator for stepping up checks and probably reducing the risks.

"This is also important given the current debate about switching some patients who don't settle on warfarin to a different kind of medication," says Lind. "The new method pinpoints these patients more accurately."


'/>"/>
Contact: Marcus Lind
lind.marcus@telia.com
46-073-831-1742
University of Gothenburg
Source:Eurekalert  

Related biology news :

1. Scalable amounts of liver and pancreas precursor cells created using new stem cell production method
2. Methods in Enzymology celebrates its 500th volume
3. New method of growing high-quality graphene promising for next-gen technology
4. Method of studying roots rarely used in wetlands improves ecosystem research
5. New method cleans up textile industrys most dangerous chemicals
6. MU researchers unveil new method for detecting lung cancer in Nature article
7. Human Gene Therapy expands with robust new methods journal
8. UH researchers work to develop screening method for superbug
9. Rice unveils new method to grow synthetic collagen
10. Novel method for increasing antibiotic yields
11. New imaging method sheds light on cell growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New method for safer dosing of anticoagulants
(Date:3/15/2016)... 15, 2016 Yissum Research Development Company ... company of the Hebrew University, announced today the formation ... technology of various human biological indicators. Neteera Technologies has ... from private investors. ... detection of electromagnetic emissions from sweat ducts, enables reliable ...
(Date:3/10/2016)... PUNE, India , March 10, 2016 ... to a new market research report "Identity and Access ... SSO, & Audit, Compliance, and Governance), by Organization Size, ... Forecast to 2020", published by MarketsandMarkets, The market is ... to USD 12.78 Billion by 2020, at a Compound ...
(Date:3/8/2016)... N.C. , March 8, 2016   ... sensor technology, today announced it has secured $11M ... by GII Tech, a new venture fund being ... with additional participation from existing investors TDF Ventures ... the funds to continue its triple-digit growth and ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... ... May 26, 2016 , ... ... are used in leading laboratories all over the globe. Their cute firefly logo ... to manufacturing awesome cuvettes, FireflySci makes spectrophotometer calibration standards that never require recalibration. ...
(Date:5/25/2016)... ... May 25, 2016 , ... Thailand’s ... at BIO 2016 in San Francisco. Located at booth number 7301, representatives from ... answer questions and discuss the Thai biotechnology and life sciences sector. , ...
(Date:5/25/2016)... Phoenix, AZ (PRWEB) , ... May 25, 2016 ... ... Arizona, Dr. Michael Fitzmaurice recently became double board-certified in surgery and surgery of ... 31, 2015. Dr. Fitzmaurice is no stranger to going above and beyond in ...
(Date:5/25/2016)... ... 25, 2016 , ... Scientists at the University of Athens say they have ... be hampering the research that could lead to one good one. Surviving Mesothelioma has ... now. , The team evaluated 98 mesothelioma patients who got a ...
Breaking Biology Technology: