Navigation Links
New method for safer dosing of anticoagulants
Date:12/6/2011

Elderly people with atrial fibrillation are often treated with anticoagulants to thin the blood, but this medicine is hard to dose and patients have to have their blood tested regularly. Researchers at the Sahlgrenska Academy at the University of Gothenburg and Chalmers University of Technology have now devised a new method that improves the accuracy of risk assessments.

Atrial fibrillation, or irregular heartbeat, is a very common heart rhythm disturbance that increases the risk of stroke and death. It is usually treated with warfarin, where the dose is calculated by measuring the coagulation of the blood. The dose is increased if coagulation is too quick, and decreased if it is too slow. Patients with unsatisfactory samples are tested more frequently, while satisfactory samples mean that the test interval can be extended.

New measurement method more reliable

In a study involving 20,000 patients in Sweden, Marcus Lind, postdoctoral researcher at the University of Gothenburg's Sahlgrenska Academy and consultant at the NU group of hospitals, tested a new measurement method that assesses far more reliably who is at risk of serious complications and admission to hospital.

"Our method takes account of how blood viscosity goes up and down," says Lind. "This meant that we could establish far more reliably which patients were at risk of a stroke, haemorrhaging or dying."

Collaboration with Chalmers

The new method also takes account of the values' extremes. "In the past we've only checked whether patients fall within the therapeutic range but the new method allows us to identify more accurately how coagulation varies both within and beyond this range," says Anders Odn, professor of biostatistics at Chalmers University of Technology, who played a key role in developing the new method.

Reduces risks

The new method improves the chances of understanding which patients are at risk of complications, and is therefore an indicator for stepping up checks and probably reducing the risks.

"This is also important given the current debate about switching some patients who don't settle on warfarin to a different kind of medication," says Lind. "The new method pinpoints these patients more accurately."


'/>"/>
Contact: Marcus Lind
lind.marcus@telia.com
46-073-831-1742
University of Gothenburg
Source:Eurekalert  

Related biology news :

1. Scalable amounts of liver and pancreas precursor cells created using new stem cell production method
2. Methods in Enzymology celebrates its 500th volume
3. New method of growing high-quality graphene promising for next-gen technology
4. Method of studying roots rarely used in wetlands improves ecosystem research
5. New method cleans up textile industrys most dangerous chemicals
6. MU researchers unveil new method for detecting lung cancer in Nature article
7. Human Gene Therapy expands with robust new methods journal
8. UH researchers work to develop screening method for superbug
9. Rice unveils new method to grow synthetic collagen
10. Novel method for increasing antibiotic yields
11. New imaging method sheds light on cell growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New method for safer dosing of anticoagulants
(Date:4/11/2017)... GARDENS, Fla. , April 11, 2017 /PRNewswire/ ... management and secure authentication solutions, today announced that ... by Intelligence Advanced Research Projects Activity (IARPA) to ... IARPA,s Thor program. "Innovation has been ... and IARPA,s Thor program will allow us to ...
(Date:4/11/2017)... April 11, 2017 No two people ... at the New York University Tandon School of ... have found that partial similarities between prints are ... in mobile phones and other electronic devices can ... The vulnerability lies in the fact that fingerprint-based ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), Biometrics, Card-Based ... & Logistics, Government & Public Sector, Utilities / Energy ... Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality & ... for a definitive report on the $27.9bn Access Control ... ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... June 22, 2017 , ... Tunnell Consulting’s ... and life sciences industries, continue to be in demand for their insights and ... be speaking on “The State of Information Governance in the Biopharmaceutical Industry” at ...
(Date:6/20/2017)... Lauderdale, Florida (PRWEB) , ... June 20, 2017 , ... ... commitment in men. While researching her latest book, Men Chase, Women Choose: The Neuroscience ... showed that love has a physiological effect on men. ”The logical next step, in ...
(Date:6/20/2017)... ... June 20, 2017 , ... GigaGen Inc ... millions-diverse immune repertoires, announces launch of its new Surge(TM) Discovery service ... CEO of GigaGen, will present on Surge at the conference. , Surge is ...
(Date:6/16/2017)... (PRWEB) , ... June 16, 2017 , ... ... device compliance and commercialization, has just announced two more sessions of its “From ... series will focus on the world of online templates for design control exercises. ...
Breaking Biology Technology: