Navigation Links
New method for associating genetic variation with crop traits

A new technique will allow plant breeders to introduce valuable crop traits even without access to the full genome sequence of that crop.

The technique, published in the journal Nature Biotechnology, links important agronomic traits in crop plants with active regions of the genome. Instead of requiring knowledge of the crop's complete genome, it identifies only expressed genes.

"For many crop plants, markers are still lacking because of the complexity of some plants' genomes and the very high costs involved," said Professor Ian Bancroft, who led the study at the John Innes Centre. "We have succeeded in developing markers based on the sequences of expressed genes, widening the possibilities for accelerated breeding through marker assisted selection."

Expressed genes are converted from genomic DNA to mRNA. Working with mRNA means that there is no need to generate a complete genome sequence from DNA, making the techniques applicable to a wide range of crops, even those with complex genomes, such as oilseed rape and wheat. It also enables the development of advanced marker resources for less studied crops that are important for developing countries or have specific medicinal or industrial properties.

The research was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the UK Department for Environment, Food and Rural Affairs (Defra).

Peter Werner of plant breeding company KWS UK Ltd and part of the research team said "KWS UK has been delighted to be involved with this ground breaking developmental research. We will be increasingly using this approach to further improve the speed and reliability of our breeding towards the continued improvement of yield and quality of our new varieties produced within the KWS group."

In partnership with the Cambridge-based bioinformatics company Eagle Genomics Ltd, the technology, called TraitTag, is being offered as a service to plant breeders. Markers associated with measured trait variation can be identified in essentially any crop species, including traits controlled at the level of gene expression variation rather than gene sequence variation, such as those with an epigenetic basis.

In an example of such an application, the researchers are now working with plant breeding company Limagrain to produce reliable markers for hybrid performance in oilseed rape. Marker-assisted breeding for this complex trait has previously been unsuccessful due to a lack of available markers and appropriate technology.

Using bioinformatics techniques it is possible to associate variation in both the sequences of expressed genes and their relative abundance in the mRNA with important traits, and then produce markers for these traits that breeders can use in their breeding programmes. Their research was published in the journal Nature Biotechnology and was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the UK Department for Environment, Food and Rural Affairs (Defra).


Contact: Andrew Chapple
Norwich BioScience Institutes

Related biology news :

1. New genomic sequencing method enables smarter anaysis of individual cells
2. Scientists develop new carbon accounting method to reduce farmers use of nitrogen fertilizer
3. Researchers develop new method for identifying lung nodules
4. TGen method isolates biospecimens for treatment of kidney disease
5. No matter the drilling method, natural gas is a much-needed tool to battle global warming
6. Stealthy microscopy method visualizes E. coli sub-cellular structure in 3-D
7. Researchers develop new method for analyzing cell function
8. New method generates cardiac muscle patches from stem cells
9. New drug-screening method yields long-sought anti-HIV compounds
10. UTMB researchers create powerful new method to analyze genetic data
11. Healing Method from Australia Addresses the Human Genome
Post Your Comments:
(Date:6/2/2016)... LONDON , June 2, 2016 ... has awarded the 44 million US Dollar project, ... Security Embossed Vehicle Plates including Personalization, Enrolment, and IT Infrastructure ... world leader in the production and implementation of Identity Management ... in January, however Decatur was selected ...
(Date:5/20/2016)... , May 20, 2016  VoiceIt is excited ... with VoicePass. By working together, VoiceIt ...  Because VoiceIt and VoicePass take slightly different approaches ... increases both security and usability. ... about this new partnership. "This marketing ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... of Infosys (NYSE: INFY ), and Samsung SDS, ... partnership that will provide end customers with a more ... payment services.      (Logo: ) ... financial services, but it also plays a fundamental part in ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016 Houston Methodist Willowbrook Hospital ... Sports Association to serve as their official health ... Methodist Willowbrook will provide sponsorship support, athletic training ... association coaches, volunteers, athletes and families. ... Sports Association and to bring Houston Methodist quality ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... announced the launch of the Supplyframe Design Lab . Located in Pasadena, ... explore the future of how hardware projects are designed, built and brought to ...
(Date:6/23/2016)... 2016 Andrew D ... Published recently in ... from touchONCOLOGY, Andrew D Zelenetz , discusses ... care is placing an increasing burden on healthcare ... therapies. With the patents on many biologics expiring, ...
(Date:6/23/2016)... 22, 2016  Amgen (NASDAQ: AMGN ) ... QB3@953 life sciences incubator to accelerate the development ... laboratory space at QB3@953 was created to help high-potential ... for many early stage organizations - access to laboratory ... Amgen launched two "Amgen Golden Ticket" awards, providing each ...
Breaking Biology Technology: