Navigation Links
New material could offer hope to those with no voice
Date:7/14/2011

CAMBRIDGE, Mass. -- In 1997, the actress and singer Julie Andrews lost her singing voice following surgery to remove noncancerous lesions from her vocal cords. She came to Steven Zeitels, a professor of laryngeal surgery at Harvard Medical School, for help.

Zeitels was already starting to develop a new type of material that could be implanted into scarred vocal cords to restore their normal function. In 2002, he enlisted the help of MIT's Robert Langer, the David H. Koch Institute Professor in the Department of Chemical Engineering, an expert in developing polymers for biomedical applications.

The team led by Langer and Zeitels has now developed a polymer gel that they hope to start testing in a small clinical trial next year. The gel, which mimics key traits of human vocal cords, could help millions of people with voice disorders not just singers such as Andrews and Steven Tyler, another patient of Zeitels'.

About 6 percent of the U.S. population has some kind of voice disorder, and the majority of those cases involve scarring of the vocal cords, says Sandeep Karajanagi, a former MIT researcher who developed the gel while working as a postdoc in the Langer lab. Many of those are children whose cords are scarred from intubation during surgery, while others are victims of laryngeal cancer.

Other people who could benefit are those with voices strained from overuse, such as teachers. "This would be so valuable to society, because every time a person loses their voice, say, a teacher or a politician, all of their contributions get lost to society, because they can't communicate their ideas," Zeitels says.

'A mechanical problem'

When Langer and his lab joined the effort in 2002, they considered two different approaches: creating a synthetic material that would mimic the properties of vocal cords, or engineering artificial vocal-cord tissue. Both approaches have potential, Langer says, but the team decided
'/>"/>

Contact: Marta Buczek
mbuczek@mit.edu
617-721-5749
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Stretching old material yields new results for energy- and environment-related devices
2. Materials scientist and entrepreneur Dr. John Rogers awarded $500,000 Lemelson-MIT Prize
3. Stevens conference explores latest innovations in antimicrobial biomaterials research
4. UH chemist investigates material for next-generation computer memory
5. The ultimate camo: Team to mimic camouflage skill of marine animals in high-tech materials
6. Researchers combine active proteins with material derived from fruit fly
7. NJIT professor develops a biologically inspired catalyst, an active yet inert material
8. Biomaterial banks for research -- clear strategies and recommendations needed
9. NC State develops material to remove radioactive contaminants from drinking water
10. Force of acoustical waves tapped for metamaterials
11. UCLA engineers demonstrate use of proteins as raw material for biofuels, biorefining
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... USA Miranda, a small, icy moon of Uranus, ... bodies in the solar system. Despite its relatively small ... intense resurfacing that resulted in the formation of at ... regions called coronae. , These coronae are visible ... least 200 km across. Arden corona, the largest, has ...
(Date:9/18/2014)... Space Station ever starts a "frequent flyers" program, fruit ... the orbiting laboratory has hosted increasing numbers of fruit ... the space station in April, and another is scheduled ... is planned to launch in December. , Fruit flies ... world-- and in space. Model organisms can reveal the ...
(Date:9/18/2014)... strands of nucleic acid that contain instructions for the ... our DNA is copied into RNA molecules, which then ... our cells. , Several years ago, scientists discovered ... known RNAs, this molecule is circular, and was labeled ... been known about how they are produced. Moreover, little ...
Breaking Biology News(10 mins):Miranda: An icy moon deformed by tidal heating 2Miranda: An icy moon deformed by tidal heating 3Miranda: An icy moon deformed by tidal heating 4Miranda: An icy moon deformed by tidal heating 5Miranda: An icy moon deformed by tidal heating 6Miranda: An icy moon deformed by tidal heating 7Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4Scientists find how mysterious 'circular RNA' is formed, claim muscular dystrophy link 2
... Management District (SJRWMD) has contracted with Florida Tech scientists ... regarding the fish larvae and eggs (ichthyoplankton) that inhabit ... a comprehensive SJRWMD effort to address public concern regarding ... St. Johns River. One measure of the ...
... developed the first small molecule that can reversibly activate ... the way for drugs that can treat low blood ... sodium channel (ENaC) controls sodium flow across many tissues ... is vital to maintaining proper salt balance and blood ...
... the fundamental laws of the universe, science is still ... about the meaning of life, the existence of God ... Is that because science is not sufficiently advanced to ... approach to science is incapable of answering humanitys deepest ...
Cached Biology News:Grant to fund answers about St. Johns River 2Finding God with biocomplexity 2Finding God with biocomplexity 3
(Date:9/19/2014)... 2014 Barnhardt Manufacturing Company ... its Organic Cotton . The USDA Certified Biobased ... biobased ingredients meets or exceeds levels set by USDA. ... whole or in significant part of agricultural, forestry, or ... Organic cotton to be immediately identified as a USDA ...
(Date:9/19/2014)... -- Dublin ... the addition of the  "Micro Market Monitor : ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , ,The ... segments in the chromatography market. The market was ... to reach $2.0 billion by 2019, at a ...
(Date:9/19/2014)... , September 19, 2014 The new ... Spain , available today on PharmaBoardroom.com for ... Eurozone crisis that rocked the Spanish economy in 2009, and ... pharma community has remained pragmatic in times of trouble. ... still the fifth biggest European market, and the general conditions ...
(Date:9/18/2014)... 2014 HealthTronics, Inc ., ... radiology products and services, announced that a poster ... cryoablation) versus external beam radiotherapy (EBRT) is being ... Urological Association (MAAUA) Annual Meeting in Baltimore, Maryland ... of Cryosurgery and External Beam Radiation as Treatments ...
Breaking Biology Technology:Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2Micro Market Monitor : Global Pre-packed Chromatography Columns 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 3HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2
... /Xinhua-PRNewswire-FirstCall/ -- China Medical,Technologies, Inc. (the "Company") ... device company that develops, manufactures and markets ... it will report selected,unaudited financial numbers including ... for the second fiscal quarter ended September ...
... Inc. ("Carna"),announced on October 27, 2008, the signing ... ("SUBC"). Under the terms of this,Agreement, SUBC will ... China., With China,s emergence as a strong ... companies have now established,research and production facilities in ...
... value and cost-effectiveness of spinal cord stimulation, ... BSX ) today welcomed an announcement by ... (NICE) recommending,the use of spinal cord stimulation (SCS) ... final guidance, NICE confirmed that,SCS is both safe ...
Cached Biology Technology:China Medical Technologies Announces Reporting Dates for the September Quarter Results and Addresses Investor Inquiries 2China Medical Technologies Announces Reporting Dates for the September Quarter Results and Addresses Investor Inquiries 3Carna Biosciences Signs Distribution Agreement with Shanghai Universal Biotech Company 2UK's NICE Recommends Spinal Cord Stimulation for Patients with Chronic Neuropathic Pain 2UK's NICE Recommends Spinal Cord Stimulation for Patients with Chronic Neuropathic Pain 3UK's NICE Recommends Spinal Cord Stimulation for Patients with Chronic Neuropathic Pain 4UK's NICE Recommends Spinal Cord Stimulation for Patients with Chronic Neuropathic Pain 5
...
No description available in Ensembl. Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
5(S)-HETE-d8 is used as an internal standard for the quantification of 5(S)-HETE by stable isotope dilution mass spectrometry....
Full-length cDNA clone CS0DJ013YG01 of T cells (Jurkat cell line) of Homo sapiens (human). [Source:Uniprot/SPTREMBL;Acc:Q86SZ3] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: