Navigation Links
New material could offer hope to those with no voice
Date:7/14/2011

CAMBRIDGE, Mass. -- In 1997, the actress and singer Julie Andrews lost her singing voice following surgery to remove noncancerous lesions from her vocal cords. She came to Steven Zeitels, a professor of laryngeal surgery at Harvard Medical School, for help.

Zeitels was already starting to develop a new type of material that could be implanted into scarred vocal cords to restore their normal function. In 2002, he enlisted the help of MIT's Robert Langer, the David H. Koch Institute Professor in the Department of Chemical Engineering, an expert in developing polymers for biomedical applications.

The team led by Langer and Zeitels has now developed a polymer gel that they hope to start testing in a small clinical trial next year. The gel, which mimics key traits of human vocal cords, could help millions of people with voice disorders not just singers such as Andrews and Steven Tyler, another patient of Zeitels'.

About 6 percent of the U.S. population has some kind of voice disorder, and the majority of those cases involve scarring of the vocal cords, says Sandeep Karajanagi, a former MIT researcher who developed the gel while working as a postdoc in the Langer lab. Many of those are children whose cords are scarred from intubation during surgery, while others are victims of laryngeal cancer.

Other people who could benefit are those with voices strained from overuse, such as teachers. "This would be so valuable to society, because every time a person loses their voice, say, a teacher or a politician, all of their contributions get lost to society, because they can't communicate their ideas," Zeitels says.

'A mechanical problem'

When Langer and his lab joined the effort in 2002, they considered two different approaches: creating a synthetic material that would mimic the properties of vocal cords, or engineering artificial vocal-cord tissue. Both approaches have potential, Langer says, but the team decided
'/>"/>

Contact: Marta Buczek
mbuczek@mit.edu
617-721-5749
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Stretching old material yields new results for energy- and environment-related devices
2. Materials scientist and entrepreneur Dr. John Rogers awarded $500,000 Lemelson-MIT Prize
3. Stevens conference explores latest innovations in antimicrobial biomaterials research
4. UH chemist investigates material for next-generation computer memory
5. The ultimate camo: Team to mimic camouflage skill of marine animals in high-tech materials
6. Researchers combine active proteins with material derived from fruit fly
7. NJIT professor develops a biologically inspired catalyst, an active yet inert material
8. Biomaterial banks for research -- clear strategies and recommendations needed
9. NC State develops material to remove radioactive contaminants from drinking water
10. Force of acoustical waves tapped for metamaterials
11. UCLA engineers demonstrate use of proteins as raw material for biofuels, biorefining
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... to an unexpected extent. The outbreak does not follow ... shows a new disease dynamic in regions, where it ... German National Academy of Sciences Leopoldina, acatech – the ... of the German Academies of Sciences and Humanities have ... In the statement the academies call for the following ...
(Date:10/15/2014)... Rosenstiel Award for Distinguished Work in Biomedical Science by ... of genomic instability and its implications for the immune ... to win the Rosenstiel Award; the first, Rod McKinnon, ... the Charles A. Janeway Professor of Pediatrics and Professor ... at the Howard Hughes Medical Institute at Boston Children,s ...
(Date:10/14/2014)... published in Cancer Research shows SIRT6—a protein ... cancers—can promote the development of skin cancers by turning ... of sun-damaged skin cells. , Previously considered protective, SIRT6 ... sirtuins that help regulate genomic stability and prevent some ... repair DNA damage, which can lead to cancer. This ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2
... paper announcing a breakthrough discovery in the fight against ... Helquist of the University of Notre Dame,s Department Chemistry ... Cornell University Weill College of Medicine, appears in the ... this week. The paper shows how use of a ...
... March 21, 2011 -- Marine biologists have solved a ... count reef fish. It may sound simple, but the ... the state of our oceans, coral reefs and the marine ... the journal Fisheries Research scientists from the University of Miami ...
... is a multicolored, tropical bird with bright blue feathers, a ... population of these birds less than 125 lives ... serious intervention, they will no longer exist. One University of ... working with farmers and residents on the island inhabited by ...
Cached Biology News:Breakthrough in Niemann-Pick Type C research reported by Notre Dame and Cornell scientists 2One fish, two fish … reef fish 2MU researcher works to save one of the world's most endangered birds 2
(Date:10/19/2014)... OCTOBER 20-22, 2014: The 9th ... will take place at the Congress Center ... is now available at http://www.abim.ch . ... organizations from all over the globe will ... latest products and developments on the world ...
(Date:10/19/2014)... 19, 2014 The Asian Automatic patient ... with analysis and forecast of revenue. The Automatic patient ... around $463.9 million by 2018, at a developing CAGR ... the TOC of the Asian Automatic patient billing market, ... This also provides a glimpse of the segmentation of ...
(Date:10/19/2014)... The Asian Orthopedic braces and support systems report ... and forecast of revenue. The Orthopedic braces and support systems ... million by 2018, at a developing CAGR of 4.4% from ... Asian Orthopedic braces and support systems market, to get an ... glimpse of the segmentation of orthopedic braces and support systems ...
(Date:10/18/2014)... The “Human Insulin Market- by Product ... Modern Human Insulin (Rapid Acting, Long Acting, Premixed)], ... Others) - Forecast to 2018” provides a detailed ... current market trends, and strategies impacting the global ... forecasts of the revenue and share analysis. , ...
Breaking Biology Technology:The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 2The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 2Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 3Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 5
... study reported in the June 2005 issue of ... predominant. But many companies, even in people businesses, ... need to excel. While organizations have perfected sophisticated ... production and flow of goods and services, their ...
... University of Wisconsin System and partners around the state have ... of Labor to create health-care training projects to help resolve ... Initiative to Fast-Track (SWIFT) Nurse Educators program, which started as ... expected to reduce the training period for nurses by anywhere ...
... ahead of the curve in implementation of healthcare technologies, ... of electronic health records is common across the United ... cost savings, implementation challenges can be daunting, notes Frances ... Healthcare Practice of Cisco Systems. , ,Significant process ...
Cached Biology Technology:Four steps to making talent management a core competence 2Four steps to making talent management a core competence 3Four steps to making talent management a core competence 4Organizations finding ways to overcome barriers to electronic health records implementation 2Organizations finding ways to overcome barriers to electronic health records implementation 3Organizations finding ways to overcome barriers to electronic health records implementation 4
... handy dispensers save space and ... hats, and other garb. They ... bins for small parts used ... Clear acrylic. Open-slot design for ...
... Microarrays designed for genome-wide microRNA ... flexible and powerful Paraflo microfluidic on-chip ... as part of our comprehensive microRNA ... Content The Mammals microRNA Microarray ...
... Proteolytic degradation is critical to ... short-lived and regulatory proteins as important ... cellular metabolism, heat shock and stress ... surface receptors and ion channels, cell ...
... Normal Pooled Human Serum • Human serum ... are found to be negative by a ... (HIV-1Ag), Antibodies to Human Immunodeficiency Virus (Anti-HIV ... for Hepatitis B Surface Antigen (HbsAg) and ...
Biology Products: