Navigation Links
New markers for acute kidney injury reported
Date:3/4/2014

LOUISVILLE, Ky. Saeed A. Jortani, Ph.D., associate clinical professor in the University of Louisville's Department of Pathology and Laboratory Medicine, headed up one of three labs in the United States involved in determining two new markers for acute kidney injury (AKI). The research group's paper, "Validation of Cell-Cycle Arrest Biomarkers for Acute Kidney Injury Using Clinical Adjudication," was posted online Feb. 25 by the American Journal of Respiratory and Critical Care Medicine.

AKI has been difficult to diagnose and treat early because current markers for it don't show up until several hours after it has begun. The research group, however, validated two new markers tissue inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein 7 (IGFBP7) in urine that, when assessed together, give clinicians the ability to detect and begin treating AKI much earlier than the current standards.

The Jortani Clinical Trials Laboratories (JCTL) at UofL were among the independent labs that tested the results of the trial. The other two were at the University of California-San Diego and ARUP Laboratories, Salt Lake City, Utah.

The JCTL is certified under the Clinical Laboratories Improvement Amendments (CLIA) of the Centers for Medicaid & Medicare Services. As a CLIA-certified lab, the JCTL has undergone a rigorous review of its facilities and processes to ensure quality in the laboratory testing and analyses it provides.

AKI was formerly known as acute renal failure. It is an abrupt loss of kidney function, usually occurring within 48 hours or less. It can occur after serious infections, major surgery or taking certain medications. In its most serious form, it can cause the patient to require dialysis and can result in death. Groups at greatest risk for AKI are the elderly, men and African Americans.


'/>"/>

Contact: Jill Scoggins
jill.scoggins@louisville.edu
502-852-7461
University of Louisville
Source:Eurekalert

Page: 1

Related biology news :

1. HUNT Biosciences and SomaLogic collaborate to validate protein biomarkers of cardiovascular risk
2. Researchers across North America team up to find genetic markers for autism
3. Genetic markers for tracking species
4. Trial seeks improved lung-cancer screening by combining imaging and biomarkers
5. Air pollution level changes in Beijing linked with biomarkers of cardiovascular disease
6. Researchers identify genetic markers to predict male fertility
7. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
8. Color-coded markers may help doctors diagnose neural diseases through the eyes
9. Molecular and protein markers discovered for liver transplant failure from hepatitis C
10. U of M researchers: Newly discovered genetic markers could signal colon cancer development
11. Is the detection of early markers of Epstein Barr virus of diagnostic value?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... WASHINGTON , April 24, 2017 ... counsel and partner with  Identity Strategy Partners, LLP ... "With or without President Trump,s March 6, ... Foreign Terrorist Entry , refugee vetting can be instilled ... refugee resettlement. (Right now, all refugee applications are ...
(Date:4/13/2017)... 2017 According to a new market research report ... Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region ... expected to grow from USD 14.30 Billion in 2017 to USD 31.75 ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
Breaking Biology News(10 mins):
(Date:5/24/2017)... ... May 24, 2017 , ... Benchworks announced that ... of the Healthcare Businesswomen’s Association (HBA). Nominated by chapter president Donna ... meets in person once each quarter and holds monthly conference calls. In addition, ...
(Date:5/24/2017)... 2017 As Ebola resurfaces in the ... 20 suspected cases now reported, a new analysis of the ... a correlation between the 2014 and 2017 outbreaks of the ... in 2012-13, which preceded the 2014 outbreak. An analysis of ... Replikin counts in 2014-15, which again precedes the current outbreak ...
(Date:5/23/2017)... ... 2017 , ... NetDimensions has been ranked as a Leader ... Corporate Learning, 2017. , Aragon Research defines Leaders as organizations who possess comprehensive ... those strategies. NetDimensions’ ranking as a Leader due to its strengths in: , ...
(Date:5/23/2017)... , ... May 23, 2017 , ... Bacterial biofilms, surface ... molecules, can cause diverse pathologies ranging from food poisoning and catheter infections to gum ... is in the tens of billions of dollars per year, there is currently a ...
Breaking Biology Technology: