Navigation Links
New map of variation in maize genetics holds promise for developing new varieties

ITHACA, N.Y. - A new study of maize has identified thousands of diverse genes in genetically inaccessible portions of the genome. New techniques may allow breeders and researchers to use this genetic variation to identify desirable traits and create new varieties that were not easily possible before.

Publishing in the Nov. 19 issue of Science, the researchers, whose senior and first author are at Cornell, have identified the first map of haplotypes sets of closely linked gene variants known as alleles in the maize genome. They have identified and mapped several million allele variants among 27 diverse inbred maize lines. The lines selected for study included a cross-section of maize types commonly used for breeding while also representing worldwide maize diversity.

The haplotype map "will help develop molecular markers and tools that breeders and geneticists around the world can use to study maize and improve maize varieties," said Ed Buckler, the paper's senior author, a USDA-ARS research geneticist in Cornell's Institute for Genomic Diversity and an adjunct professor of plant breeding and genetics. Michael Gore, a graduate student in Buckler's lab, is the paper's lead author.

The other co-authors are affiliated with the U.S. Department of Agriculture's Agricultural Research Service (USDA-ARS), Cold Spring Harbor Laboratory and University of California-Davis.

In the last century, maize breeders have found limitations in recombination (the ability to shuffle genetic variation), where large regions genetic material fail to recombine near the chromosome's center, called the centromere. To overcome this, breeders have crossed two complementary lines, resulting in a new line with higher yields and vigor.

However, because large regions of the maize chromosome are less accessible, breeders cannot arrive at optimal genetic combinations.

The study has revealed a great deal of genetic variation near the chromosomes' centromeres, which resist recombining. Now, breeders can use molecular markers to identify desirable genetic variants and new genetic technologies to move the desired variation onto the same chromosomes and create new, more productive lines with desired traits.

The study revealed more than 100 large regions (selective sweeps) on the genome where breeders selected for a gene during domestication. In doing so, genetic diversity was lost around those genes.

The study also identified regions of genes shared by all maize species as well as regions that are different based on the geographic adaptations of lines of plants. For example, the study identified almost 200 highly differentiated regions that result from adaptations in tropical and temperate maize.

"This survey of genetic diversity provides a foundation for uniting breeding efforts across the world and for dissecting complex traits through genomewide association studies," said Buckler.

The first complete sequence of the maize genome appears in the same issue of Science.


Contact: Blaine Friedlander
Cornell University

Related biology news :

1. New book presents successful strategies for probing genetic variation
2. Physician-scientists seek solutions to reproductive problems related to chromosomal variations
3. Copy number variation may stem from replication misstep
4. Gene variation may elevate risk of liver tumor in patients with cirrhosis
5. DNA variations signal lupus risk
6. U-M researchers release most detailed global study of genetic variation
7. Michigan Tech researchers link 11 genetic variations to type 2 diabetes
8. Mental stress reduces blood flow to the heart in patients with gene variation
9. Genetic variation linked to sugary food
10. Statistical tool could explain gene study variations
11. Why do people vote? Genetic variation in political participation
Post Your Comments:
(Date:10/26/2015)... NEWARK, Calif. , Oct. 26, 2015  Delta ... convenient biometric authentication to mobile and PC devices, announced ... Fujitsu,s smartphone, the arrows NX F-02H launched by NTT ... arrows NX F-02H is the second smartphone to include ... this technology in ARROWS NX F-04G in May 2015, ...
(Date:10/23/2015)... and GOLETA, California , October ... conference, BIOPAC and SensoMotoric Instruments (SMI) announce a mobile ... tracking data captured during interactive real-world tasks ... play integration of their established wearable solutions for eye ... synchronize gaze behavior captured with SMI Eye Tracking ...
(Date:10/22/2015)...  Synaptics (NASDAQ: SYNA ), a leading developer of human ... September 30, 2015. --> --> ... 66 percent over the comparable quarter last year to $470.0 million. ... million, or $0.62 per diluted share. --> ... of fiscal 2016 grew 39 percent over the prior year period ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman and ... early in their initial angel funding process. Now, they are paying it forward ... make early stage investments in the microbiome space. In this, they join ...
(Date:11/24/2015)... /CNW/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... the quarter ended September 30, 2015. Amounts, unless ... presented under International Financial Reporting Standards ("IFRS"). ... Andrew Rae , President & CEO of ... only value enriching for this clinical program, but ...
(Date:11/24/2015)... , November 24, 2015 ... new market research report "Oligonucleotide Synthesis Market by Product ... (PCR, Gene Synthesis, Diagnostic, DNA, RNAi), End-User (Research, Pharmaceutical ... published by MarketsandMarkets, the market is expected to reach ... in 2015, at a CAGR of 10.1% during the ...
(Date:11/24/2015)... , Nov. 24, 2015  Tikcro Technologies Ltd. (OTCQB: TIKRF) today ... December 29, 2015 at 11:00 a.m. Israel time, ... Tower, 98 Yigal Allon Street, 36 th Floor, Tel ... Eric Paneth and Izhak Tamir to the Board ... Skaliter as external directors; , approval of an amendment to certain ...
Breaking Biology Technology: