Navigation Links
New lung cancer study takes page from Google's playbook
Date:3/25/2013

SAN DIEGO - The same sort of mathematical model used to predict which websites people are most apt to visit is now showing promise in helping map how lung cancer spreads in the human body, according to a new study published in the journal Cancer Research.

A team of researchers used an algorithm similar to the Google PageRank and to the Viterbi Algorithm for digital communication to analyze the spread patterns of lung cancer. The team includes experts from the University of Southern California (USC), Scripps Clinic, The Scripps Research Institute, University of California, San Diego Moores Cancer Center and Memorial Sloan-Kettering in New York.

"This research demonstrates how similar the Internet is to a living organism," said USC Viterbi School of Engineering Professor Paul Newton, Ph.D., the lead and corresponding author of the study. "The same types of tools that help us understand the spread of information through the web can help us understand the spread of cancer through the human body."

Employing a sophisticated system of mathematical equations known as a Markov chain model, the research team guided by USC applied mathematicians found that metastatic lung cancer does not progress in a single direction from primary tumor site to distant locations, which has been the traditional medical view. Instead, they found that cancer cell movement around the body likely occurs in more than one direction at a time.

Researchers also learned that the first site to which the cells spread plays a key role in the progression of the disease. The study showed that some parts of the body serve as "sponges" that are relatively unlikely to further spread lung cancer cells to other areas of the body. The study identified other areas as "spreaders" for lung cancer cells.

The study revealed that for lung cancer, the main spreaders are the adrenal gland and kidney, whereas the main sponges are the regional lymph nodes, liver and
'/>"/>

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. Embryonic development protein active in cancer growth
3. BRG1 mutations confer resistance to hormones in lung cancer
4. Genetic variation in East Asians found to explain resistance to cancer drugs
5. Beyond the microscope: Identifying specific cancers using molecular analysis
6. Marshall University study may lead to new treatments for prostate cancer
7. Salk scientists open new window into how cancers override cellular growth controls
8. Penn research points to new way of preserving fertility for boys undergoing cancer treatment
9. Genetic abnormality offers diagnostic hope for childrens cancer
10. Protein jailbreak helps breast cancer cells live
11. Breast cancer risk gene discovery fast tracked by new technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research ... announced the addition of the "Global Facial ... http://photos.prnewswire.com/prnh/20130307/600769 ... the identification of individuals. Facial recognition system measures ... as nose, jaw edges, mouth, and the distance ...
(Date:12/11/2014)... ST. PAUL, Minn. , Dec. 10, 2014 ... in wireless physiologic monitoring, has released a new ... changing needs of preclinical toxicology researchers. M series, ... to help toxicologists collect the best possible physiologic ... studies. Adding functional endpoints to toxicology ...
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... some of North Africa,s major droughts of centuries past, ... the year 1179. The first multi-century drought reconstruction ... severe droughts during the 13th and 16th centuries and ... An international research team figured out northwest Africa,s climate ...
... Spanish . A new model for manipulating vitamin ... Service (ARS) scientists who say it could help establish just how ... optimal growth and health. Newborn dairy calves get crucial vitamin ... the first few days after birth. Later, the neonatal calf ...
... 25, 2010An insightful and in-depth presentation of the most ... pediatric interstitial lung disease (ILD) is presented in a ... Pediatric Allergy, Immunology, and Pulmonology (PED), a peer-reviewed ... ). The entire issue is available free online. ( ...
Cached Biology News:20th century one of driest in 9 centuries for northwest Africa 220th century one of driest in 9 centuries for northwest Africa 3Model developed for manipulating vitamin D levels in calves 2Comprehensive overview of Children's Interstitial Lung Disease (chILD) in special issue of Pediatric Allergy, Immunology, and Pulmonology 2
(Date:12/24/2014)... report expects global cell isolation and expansion market to ... carefully analyzed data about the vital drivers, restraints, trends, ... Copy of Report @ http://bit.ly/1yUxy0T , According ... will keep witnessing growth at an impressive CAGR during ... by rapid technological advancements, government funding and investments, and ...
(Date:12/24/2014)... -- PharmaBoardroom,s new report, , Healthcare ... for free download , digs deep into this vibrant ... the sector today. One area where ... developing a homegrown pharmaceutical manufacturing base, even if the government,s ... way off. A cursory comparison with neighboring Morocco ...
(Date:12/22/2014)... PA & Brussels (PRWEB) December 22, 2014 ... (CfPIE), the global leader of technical training across ... Society for Clinical Data Management (SCDM) to provide ... and certification programs —providing access to the more ... partnership extends SCDM members with 10% off when registering ...
(Date:12/22/2014)... GenomeDx Biosciences today announced that a new ... genomic test for prostate cancer, was able to predict ... radical prostatectomy without adjuvant therapy. Although rapid metastasis in ... tumor genomics to identify these men who have a ... advance. The study has been published online by ...
Breaking Biology Technology:The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3
... Aug. 30 Pressure,BioSciences, Inc. (Nasdaq: ... has been,issued its first patent by the ... Biomolecular Complexes" (Number,2,259,318), this issuance extends the ... patents previously issued in the United States,Japan, ...
... SOUTH SAN FRANCISCO, Calif., Aug. 30 VaxGen,Inc. ... filed with the,Securities and Exchange Commission (SEC) its ... December 31, 2006 and Quarterly Reports on Form ... reports can be found at the link titled,"SEC ...
... of the FDA,s,Cooperative Research and Development Agreement (CRADA) ... (FDA) on August 23, 2007, in a,presentation focusing ... at,the Third Annual Regulatory and Compliance Symposium -- ... was held at Harvard University. Helen Winkle, ...
Cached Biology Technology:Pressure BioSciences, Inc. Issued First Patent in Canada 2Pressure BioSciences, Inc. Issued First Patent in Canada 3VaxGen Files 2006 Financial Statements and Provides Cash Update 2FDA and Conformia Deliver Joint Presentation to Annual Regulatory and Compliance Symposium at Harvard 2FDA and Conformia Deliver Joint Presentation to Annual Regulatory and Compliance Symposium at Harvard 3
... These handy dispensers save space ... hats, and other garb. They are ... small parts used in labs, processing ... static charges and the particles they ...
... Double staining is a technique used ... single tissue.(1-6) PicTure™-Double Staining Kit is a ... detecting two antigens simultaneously in the same ... sensitivity. The antigens can be identified using ...
... NOVOstar is an exciting product for cell-based ... assays required the use of expensive HTS ... scientists in the assay development stage. The ... cell-based assays as well as any other ...
... the DH-2000, but comes with a shutter (controlled ... 5 Hz) The DH-2000 Deuterium ... of deuterium and tungsten halogen light sources in ... produces a powerful, stable output from 215-200 nm. ...
Biology Products: