Navigation Links
New low-cost method to deliver vaccine shows promise
Date:11/15/2010

Asian countries."

"The vaccine with the Bacillus bacteria is very inexpensive to produce in large quantities and, unlike most traditional vaccines, requires no special purification steps before use. As a result, the cost of vaccine production is unusually low," explained Saul Tzipori, BVSc (DVM), DSc, PhD, Agnes Varis University Chair in Science and Society, distinguished professor of microbiology and infectious diseases, and director of the infectious diseases division of the department of biomedical sciences at the Cummings School. These findings are consistent with the team's previous studies in which they demonstrated that B. subtilis bacteria displaying a fragment of tetanus toxin protein completely protect mice from tetanus. Tetanus vaccines have been stored for more than a year at 113F without any loss of potency, a property that may be common to all B. subtilis vaccines.

Vaccines currently available have to be stored in refrigerators or freezers until the moment they are administered. This cold chain is difficult and costly to maintain. In many parts of the world, there is insufficient refrigeration or electricity to keep vaccines cold. The lack of refrigeration combined with the lack of trained personnel, especially in rural areas in developing countries, make it impossible for many children and adults to be vaccinated against standard infections, such as tetanus, rotavirus, diphtheria, pertussis (whooping cough) and other diseases.

"In addition to being heat-stable and low-cost, the B. subtilis vaccines are given in the form of nasal drops or spray. A needle-free approach to vaccination is particularly advantageous in developing countries where clean needles and syringes and trained personnel are not always available," said team leader Abraham L. (Linc) Sonenshein, PhD, professor and acting chair of molecular biology and microbiology at TUSM and member of the genetics and microbiology program faculties at the Sackler School of G
'/>"/>

Contact: Siobhan E. Gallagher
617-636-6586
Tufts University, Health Sciences
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Undergraduates low-cost ultrasound system wins Gates Foundation grant
2. Low-cost, ultra-fast DNA sequencing brings diagnostic use closer
3. Simple, low-cost steps enhance adolescents health
4. Covering the bases: Quantum effect may hold promise for low-cost DNA sequencing, sensor applications
5. Pilot study shows effectiveness of new, low-cost method for monitoring hand hygiene compliance
6. Cellulosic biofuel technology will generate low-cost green fuel, says major study
7. High Performance, Low-Cost VoIP Chips Address Critical Performance Issues Such as Echo, Latency, and Packet Loss
8. Fast-track gene-ID method speeds rare disease search
9. OU study on genetics in fruit flies leads to new method for understanding brain function
10. New method successfully predicted how oil from Deepwater Horizon spill would spread
11. University at Buffalo symposium on in silico methods, high throughput screening
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New low-cost method to deliver vaccine shows promise
(Date:4/23/2014)... is a technique used to read quickly. It ... skipping non-essential words and/ or sentences. Similarly to ... to quickly "read" genetic information. Genes that need ... the smaller the encoding message, the easier it ... from Instituto Gulbenkian de Cincia (IGC, Portugal) and ...
(Date:4/22/2014)... of Yale researchers will lead a five-year, $3 million ... events is affecting the transport of dissolved organic matter ... say could alter the chemical composition and water quality ... funding from the National Science Foundation,s MacroSystems Biology program, ... the watershed, which begins in Canada and runs through ...
(Date:4/22/2014)... International Science Consortium Ltd.,s nanotechnology expert will present a ... hazard assessment" at the 7th International Nanotoxicology Congress ... Turkey. , Dr. Monita Sharma will outline a ... National Academy of Sciences, " Toxicity Testing in the ... recommends use of non-animal methods involving human cells and ...
Breaking Biology News(10 mins):Cell division speed influences gene architecture 2Connecticut River watershed study will assess impacts of extreme rain events 2Connecticut River watershed study will assess impacts of extreme rain events 3
... 2012 The Crop Science Society of America (CSSA) announces ... their Annual Meetings, Oct. 21-24, 2012 in Cincinnati, OH. Members ... achievements and meritorious service. Only 0.3 percent of the Society,s ... class of CSSA Fellows are: Marc C. Albertsen, ...
... biological cells like a skin. They also surround organelles ... division. Scientists have long known in principle how biomembranes ... a role in maintaining the optimal distance between neighboring ... with the help of computer simulations, scientists of the ...
... Bioluminescence may play a key role in successful foraging ... research published Aug. 29 in the open access journal ... led by Jade Vacqui-Garcia, monitored the diving behaviour of ... Ocean that were also equipped with light detectors. The ...
Cached Biology News:Crop Science Society of America presents 2012 class of fellows 2Crop Science Society of America presents 2012 class of fellows 3Keep your distance! Why cells and organelles don't get stuck 2
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 ... Almshouse Road, Warrington, Pa. , Details: The Hepatitis ... finding a cure for hepatitis B and improving the quality ... Crystal Ball on Friday, April 11 at Warrington Country Club ...
(Date:1/14/2014)... NY (PRWEB) January 14, 2014 EquitiesIQ, ... Alliqua, Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical ... serve the wound care market. , Free report download: ... restructured with a seasoned management team and Board, which ...
(Date:1/14/2014)... , Jan. 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: ... and commercializing innovative therapies addressing major unmet medical ... received the Notice of Allowance from the United ... self-delivering RNAi compounds (sd-rxRNA®), for the treatment of ...
(Date:1/14/2014)... Rochester, NY (PRWEB) January 14, 2014 During ... is now known as “The Doctor’s Plague.” In this time ... their hands. This led, at times, to the death of ... staff today don’t know that they may be unwittingly transmitting ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... EASTON, Mass., March 6 Pressure,BioSciences, Inc. (Nasdaq: ... teleconference to discuss its 2007 financial results and to ... teleconference either,by telephone or through a live web-cast. The ... March 12, 2008, Time: 4:30 p.m. Eastern Daylight ...
... to Support European Partnerships, ALAMEDA, Calif., and ... collaboration with Novartis Pharma AG to give Novartis,access ... Technology Access Program (ETAP). Terms of the collaboration,were ... opening of a,facility in Paris, France to support ...
... Recently the State of,Brandenburg, and the EU, ... Alcat Europe, GmbH, covering marketing and employee costs ... laboratory company located in the BioTech Park in,Hennigsdorf ... food and,chemical sensitivities through the Alcat test method. ...
Cached Biology Technology:Pressure BioSciences, Inc. to Discuss 2007 Financial Results and Provide Business Update 2Singulex Collaborates With Large Pharmaceutical Company in Erenna(TM) Technology Access Program 2European Union, State of Brandenburg, Award Grants to Alcat Europe, GmbH 2
... Sequencer 20 System revolutionizes DNA sequencing, delivering ... The Genome Sequencer 20 System includes: ... and consumables for library construction, amplification, and ... de novo assembly The ...
... The RapidVUE is a particle shape and ... has been designed with the utmost simplicity in ... sample delivery module and an optical bench. The ... allows for easy upgrade for different applications such ...
... The ProteoSpin Detergent Clean-up Micro Kit provides ... removal of SDS, Triton X-100 and other detergents ... spin-column chromatography using Norgens patented protein resin as ... processing 2 50 g of either acidic or ...
... degradation is critical to the maintenance ... regulatory proteins as important and diverse ... heat shock and stress response, antigen ... and ion channels, cell cycle regulation, ...
Biology Products: