Navigation Links
New insights into treatment options for patients suffering from severe alcoholic hepatitis
Date:4/16/2010

Vienna, Austria, Friday 16 April 2010: Results from two French studies presented today at the International Liver CongressTM 2010 press conference will help inform clinical practice in the treatment of patients with severe or acute alcoholic hepatitis.

The first study demonstrated the positive potential of performing liver transplantation for patients suffering from severe alcoholic hepatitis (SAH) earlier than the recommended 6-months rule (required minimum of recorded abstinence for an alcoholic patient to be eligible for a liver transplant). Indeed, those patients who do not respond to treatment with steroids have a 6-month survival of around 30% and most deaths actually occur within 2-months. The results show that early liver transplantation could be proposed to non-respondents, pending a very careful evaluation of selected patients.

Acute alcoholic hepatitis (AAH) however, is an absolute contraindication for liver transplantation. It has a low survival rate, with mortality remaining at around 35% at 6 months despite corticoid treatment, the current standard of care for the condition. The second study presented today will help inform a potential new treatment option for those patients who do not respond to standard treatment with corticoid. Data demonstrated that treatment with combined corticoids plus N-acetyl cysteine (C+NAC) showed an increase in survival rates. There have been few, large, well-designed trials advocating the use of N-acetyl cysteine to slow progression of liver disease. This latest study adds to the growing body of evidence in the benefits of treatment with C+NAC in patients with acute liver disease.

Professor Philippe Mathurin from the Hpital Huriez, CHRU Lille, France who presented the results commented: "Whilst the management of alcoholic hepatitis is steeped in controversy, as clinicians we have a responsibility to treat these patients in the most effective way possible, and as researchers we have a mand
'/>"/>

Contact: Isabelle Scali
media.easl2010@cohnwolfe.com
44-771-743-5103
European Association for the Study of the Liver
Source:Eurekalert

Page: 1 2

Related biology news :

1. Stomach stem cell discovery could bring cancer insights
2. KGI professor contributes new insights on jumping genes
3. Study involving more than 100 scientists provides new insights on green algae
4. New insights into how lasers cut flesh
5. Tumor genome analysis unveils new insights into lung cancer
6. New insights into the fate of antiparasitics in manure and manured soils
7. Hinode: new insights on the origin of solar wind
8. New mechanical insights into wound healing and scar tissue formation
9. Antarctic expedition provides new insights into the role of the Southern Ocean for global climate
10. New dinosaur from Mexico offers insights into ancient life on West America
11. New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... , May 27, 2015   ... medication safety systems and image documentation solutions ... of comprehensive, technologically-advanced automation solutions, is pleased ... integration. The Codonics® Safe Label System® (SLS), ... in conjunction with the Omnicell Anesthesia Workstation, ...
(Date:5/22/2015)... According to a new market research report ... by Software (Middleware, Databases), by Hardware (Cameras, Integrated Devices), ... - Global Forecast to 2020", published by MarketsandMarkets, Facial ... to $6.19 Billion by 2020, at a CAGR of ... and   43 Figures spread through 140 Pages and ...
(Date:5/20/2015)... OXFORD, Conn. , May 20, 2015 ... "Company") announces that its wholly owned subsidiary, 3D-ID LLC, ... contractor under Team Battelle for the biometrics technology portion ... Unrestricted Suite Contract from the Department of the Army. ... facial recognition products developed for government, law enforcement and ...
Breaking Biology News(10 mins):Codonics and Omnicell Expand Partnership 2Codonics and Omnicell Expand Partnership 3Codonics and Omnicell Expand Partnership 4Facial Recognition Market Worth $6.19 Billion by 2020 2Facial Recognition Market Worth $6.19 Billion by 2020 3NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3
... Francisco have launched a groundbreaking study to determine whether ... the most common congenital chest deformity, in the same ... chest, which is known medically as pectus excavatum, is ... to the breastbone. The deformed cartilage pulls the breastbone ...
... recurrent cancer of the central nervous system that occurs primarily ... a clinical trial at the University of California, San Francisco. ... is always fatal. Findings from a group of 12 ... effective in stimulating the patient’s immune system to attack ...
... that chimpanzees from West Africa were cracking nuts with ... years ago. The result suggests chimpanzees developed this behaviour ... was a trait inherited from our common ancestor. Julio ... the Noulo site in Cote d'Ivoire, the only known ...
Cached Biology News:Study to explore using magnets to correct 'sunken chest' 2Study to explore using magnets to correct 'sunken chest' 3UCSF brain tumor vaccine trial shows promising results 2UCSF brain tumor vaccine trial shows promising results 3The chimpanzee stone age 2
(Date:6/3/2015)... Typical racks for laboratory freezers are generally ... often taking up unnecessary room in already crowded freezers. ... Box Freezer Racks offer a customizable storage solution ... boxes and freezers. , “These racks are perfect ... multiple people because users can configure freezer space to ...
(Date:6/3/2015)... Green Earth Energy has restructured their ... the RCBC Waste to Energy system. Paul Douglas ... family business, http://www.greenearthwaste.com which has been operating ... recycling to their waste collection services in 2012 and ... Fortune 500 companies with manufacturing plants in West Tennessee. ...
(Date:6/3/2015)... REYKJAVIK, Iceland , June 3, 2015   ... genome to improve health worldwide, today announced that it ... to provide clinical interpretation of the whole genome sequences ... of the first phase of the 100,000 Genomes Project ... WuXi NextCODE will deploy its unique database ...
(Date:6/3/2015)... June 03, 2015 Global Stem ... Inc. have announced plans to conduct Romania’s first ever ... Through an alliance with Miami-based Stem Cell Training, Inc., ... the Adipose and Bone Marrow Stem Cell Training Course ... reconstructive plastic surgery specialist practicing in Bucharest and Tel ...
Breaking Biology Technology:Freezer Space Can Now Be Configured Your Way with New Modular Freezer Racks 2WuXi NextCODE Wins Genomics England Clinical Interpretation Tender in both Rare Disease and Cancer 2Global Stem Cells Group Announces First Stem Cell Training Course to Take Place in Romania 2Global Stem Cells Group Announces First Stem Cell Training Course to Take Place in Romania 3
... Jersey, October 29, Rosetta Genomics Ltd. (Nasdaq: ROSG ... announced today its,management will present at Oppenheimer 19th ... the Waldorf-Astoria Hotel in New York,City., About ... occurring, small,RNAs that act as master regulators and ...
... /Xinhua-PRNewswire/ -- Sinovac Biotech Ltd. (Amex:,SVA), a vaccine-focused ... scheduled to present at two upcoming investor conferences, ... York City and the,Credit Suisse Asian Healthcare Conference ... Financial Manager, is scheduled to present on,Tuesday, November ...
... Osteotech, Inc.,(Nasdaq: OSTE ), a leader ... healing, announced today that it has received 510(k) ... ("FDA") for its next,generation grafting material. Osteotech received ... substitute, and as a bone void filler, for ...
Cached Biology Technology:Rosetta Genomics to Present at Oppenheimer's 19th Annual Healthcare Conference 2Rosetta Genomics to Present at Oppenheimer's 19th Annual Healthcare Conference 3Sinovac to Participate in Two Upcoming Investor Conferences 2Osteotech Receives FDA Clearance for its Next Generation Grafting Material 2