Navigation Links
New insights into a leading poultry disease and its risks to human health
Date:1/27/2009

Biodesign Institute at Arizona State University associate research scientist Melha Mellata, a member of professor Roy Curtiss' team, is leading a USDA funded project to develop a vaccine against a leading poultry disease called avian pathogenic E. coli (APEC).

APEC is part of a large, diverse group of microbes called extra-intestinal pathogenic E. coli (ExPEC). They cause a number of complex brain, lung and urinary tract diseases in human, animals, and birds. There is also considerable concern in the scientific community that APEC strains are becoming an emergent food pathogen. The poultry products are a suspected source of a suite of ExPEC infections, including those causing human disease.

The U.S. is the leading poultry industry in the world at an annual value of more than $50 billion, and E. coli infections are a big threat, causing millions in losses for the industry. According to the USDA, the two most common types of poultry infections are from the bacteria E. coli and Salmonella.

Antibiotics have long been the first line of defense to prevent APEC, but have lost their potency, as the bacteria have grown increasingly resistant to treatment. How these microbes cause disease is poorly understood. Mellata and colleagues in the institute's Center for Infectious Diseases and Vaccinology, led by Roy Curtiss, have been hard at work to understand the molecular tricks these bacteria use to evade a host's immune system.

Now, in a paper published in the journal PLoS One (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0004232), Mellata's team has analyzed the DNA sequence of a critical genetic element of APEC that contains several genes responsible for triggering its harmful effects. In addition, by comparing these genes to a collection of human ExPEC strains, they have shown that human and a
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Mixing genomics and geography yields insights into life and environment
2. New papers offer insights into process of malarial drug resistance
3. St. Jude study gives new insights into how cells accessorize their proteins
4. New insights into the regulation of PTEN tumor suppression function
5. Deep sequencing study reveals new insights into human transcriptome
6. Insights into micromillimeters
7. Study of marine snail leads to new insights into long-term memory
8. Researchers reveal insights into hidden world of protein folding
9. Metagenomics of skin reveals insights into the human microbiome
10. First study hints at insights to come from genes unique to humans
11. New insights into the diversity of Creutzfeldt-Jakob disease agents
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New insights into a leading poultry disease and its risks to human health
(Date:7/8/2015)... 2015 The consumer products industry for ... have products such as wearables, smart wallets & other smart ... based devices continues to rapidly grow.  Biometrics & Wearable Device ... ), Google Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... Inc. (NASDAQ: GPRO ) and Baidu Inc. (NASDAQ: ...
(Date:7/7/2015)... , July 7, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... the growing mobile commerce market announces a revised version of one ... The commercial will air on CNBC in New York ... and San Francisco metro areas. ... focuses on Wocket,s ability to replace all the cards in your ...
(Date:7/2/2015)... Fingerprint Cards has received an order ... from the distributor World Peace Industrial Group (WPI), part of ... Asia . Deliveries are planned to take place ... by smartphone manufacturers in Asia . The ... revenue guidance of approximately 2,200 MSEK for 2015. ...
Breaking Biology News(10 mins):Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... Award on 25 March 2009 at the Spring Scientific Meeting ... the State Department of Agriculture & Food, Backweston Campus, Ireland. ... who is actively involved in and has made a substantial ... meeting was attended by about 30 members of the Society ...
... record usually shows what adult animals looked like. But ... dramatically from those of the adults. A classic example ... Uppsala, Cambridge and Duke Universities, published in Science ... animals also underwent such changes of lifestyle as they ...
... in Spanish . , KRas is one ... that is mutated in 30% of human tumors and has ... For this reason, it is one of the main focuses ... to publish new information relating to its molecular biology. Researchers ...
Cached Biology News:The life histories of the earliest land animals 2New data on the breakdown of the KRas protein 2
(Date:7/29/2015)... , July 29, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: ... the Company,s Chief Financial Officer has resigned.  The Company ... Financial Officer who retired in December 2014, as full ... a permanent successor.     Andy Ashworth ... and ensure a smooth transition.  Andy was the Company,s ...
(Date:7/29/2015)... DUBLIN , July 29, 2015 ... ) has announced the addition of the ... to their offering. The Global Biosimilars ... study of the rapidly growing biosimilars market. With ... industry striving to minimize costs, biosimilars are being ...
(Date:7/29/2015)... SAN DIEGO , July 29, 2015  Pfenex ... quarter 2015 financial results will be released on Thursday, ... 8:30 am Eastern Time, Pfenex management will host a ... a business update.  A press release outlining the financial ... to the call. Please call 1-866-376-8058 (US) ...
(Date:7/29/2015)... QUEBEC CITY , July 29, 2015 /PRNewswire/ ... (the "Company") today announced it has selected an optimized ... important milestone in the development of a new ... The MAPK pathway represents a prime target for ... significant antitumor activities and survival benefits for B-Raf ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3Pfenex To Report Second Quarter 2015 Results and Provide Business Update on Thursday, August 13, 2015 2Aeterna Zentaris Announces Optimized Erk Inhibitor Compounds For Further Development 2Aeterna Zentaris Announces Optimized Erk Inhibitor Compounds For Further Development 3
... , NEWPORT, Ky., July 13 ... development and commercial capabilities focused on women,s healthcare and pain ... its executive management team. Joining the company are Natasha ... Officer; and Peter Wentworth, Senior Vice President, Human Resources. ...
... PHILADELPHIA and LONDON, July 13 Thomson Reuters today ... the last two decades in both the volume and impact of ... findings underscore Brazil,s standing among the emergent "BRIC" nations. BRIC ... the countries possessing the resources and economic potential to capture a ...
... HOLMDEL, N.J., July 13 Sparta Systems, ... management software, today announced that Cangene Corporation, a ... Sparta,s TrackWise ((R)) Enterprise Quality Management software to ... operations in Canada and the United States. After ...
Cached Biology Technology:Xanodyne Announces New Executive Team Members 2Brazil's Scientific Research On The Rise, Thomson Reuters Study Finds 2Sparta Systems' TrackWise(R) Solution Delivers Workforce Training and Learning Initiatives for Cangene Corporation 2Sparta Systems' TrackWise(R) Solution Delivers Workforce Training and Learning Initiatives for Cangene Corporation 3Sparta Systems' TrackWise(R) Solution Delivers Workforce Training and Learning Initiatives for Cangene Corporation 4
... to reward the animal for foraging behavior.The Spatial ... built around a video camera, frame grabber, and ... fields at once and up to 6 moving ... records them, but also allows video replay of ...
... Feature Extraction Software reads and ... to prepare microarray data for ... * one 1-year license ... NFP/Academic accounts ,one CD-ROM containing ...
... Last innovation from Magnetofection technology, ... delivery system available. Simple, rapid and ... compatible and non toxic. Specifically designed ... gene silencing at very low doses ...
... DW4 liquid handling system from Molecular Devices ... in one instrument. The system handles a ... plate washing96-, 384- and 1536-welland is the ... DW4 has been optimized to dispense from ...
Biology Products: