Navigation Links
New infant formula ingredients boost babies' immunity by feeding their gut bacteria
Date:2/29/2012

URBANA Adding prebiotic ingredients to infant formula helps colonize the newborn's gut with a stable population of beneficial bacteria, and probiotics enhance immunity in formula-fed infants, two University of Illinois studies report.

"The beneficial bacteria that live in a baby's intestine are all-important to an infant's health, growth, and ability to fight off infections," said Kelly Tappenden, a U of I professor of nutrition and gastrointestinal physiology. "Breast-fed babies acquire this protection naturally. Formula-fed infants get sick more easily because the bacteria in their gut are always changing."

The idea is to make formula more like breast milk by promoting the sorts of intestinal bacteria that live in breast-fed babies' intestines, she added.

Prebiotics are carbohydrates that resist digestion by human enzymes and stimulate the growth and activity of beneficial bacteria in the gastrointestinal tract.

Probiotics are actual live bacteria that are beneficial to intestinal health, she said.

Infants have a special need for stimulation of their gut microbiota because they are born with a sterile intestine, Tappenden said.

"A strong, robust population of microbes in the gut provides colonization resistance, and pathogens can't invade and infect an infant who has that resistance as easily," she added.

The researchers compared the effects of feeding pre- and probiotics with infants fed breast milk and control formulas. They also compared the enhanced formulas' effects in both vaginally and Caesarean-delivered babies.

"The probiotic formula significantly enhanced immunity in formula-fed infants," Tappenden said.

Also, babies delivered by C-section had an especially improved immune response, an important finding because C-section babies are a more vulnerable group, she said.

Why? "Babies delivered naturally are exposed to the mother's bacteria as they travel through the birth canal, and they develop a healthier population of gut bacteria as a result. Babies delivered by C-section enter a sterile environment, and their gut microbiota is quite different," Tappenden noted.

In the probiotics study, scientists at five sites divided 172 healthy six-week-old infants into two formula-fed groups and a breast-fed group. Beginning at six weeks of age, the formula-fed groups received either a control formula or a formula that contained the beneficial bacteria Bifidobacterium animalis subspecies lactis (Bb12) for a six-week period. The infants receiving the probiotic formula had increased concentrations of secretory, anti-rotavirus, and anti-poliovirus-specific immunoglobulin A (IgA).

Fecal samples from babies receiving the probiotic formula revealed significantly heightened immunity, especially among Caesarian-delivered infants, Tappenden said

Infants who consumed the formula containing the prebiotic ingredients also benefited. In that study, 139 healthy babies were divided into three groups. Breast-fed infants were compared with babies fed either a control formula or a formula supplemented with galacto- and fructo-oligosaccharides for six weeks.

Oligosaccharides, found in breast milk, contribute to the healthy population of bacteria found in the guts of breast-fed infants.

When fecal samples were tested, babies fed the prebiotic formula showed modest improvement in the number of beneficial bacteria and decreases in the types of bacteria that are often associated with illness.


'/>"/>
Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences
Source:Eurekalert

Related biology news :

1. Brown University and Women & Infants Hospital expand national childrens study to Bristol County
2. Biomarkers for identifying infant infections
3. Baby talk: The roots of the early vocabulary in infants learning from speech
4. UNC, Yale partner to study effects of cocaine use on mother-infant relationships
5. UNC expands brain imaging study of infants at risk for autism
6. Vitamin D deficiency in infants and nursing mothers carries long-term disease risks
7. Benefits of breastfeeding outweigh risk of infant exposure to environmental chemicals in breastmilk
8. New infant formula safety advice could prevent infant suffering
9. New infant feeding and obesity research adds insight to ongoing issue
10. Research exposes the risk to infants from the chemicals used in liquid medicines
11. New evidence explains poor infant immune response to certain vaccines, says MU researcher
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/1/2016)... NEW YORK , June 1, 2016 ... Biometric Technology in Election Administration and Criminal Identification to ... According to a recently released TechSci Research report, " ... Sector, By Region, Competition Forecast and Opportunities, 2011 - ... $ 24.8 billion by 2021, on account of growing ...
(Date:5/9/2016)... May 9, 2016 Elevay is ... to expanding freedom for high net worth professionals seeking ... today,s globally connected world, there is still no substitute ... ever duplicate sealing your deal with a firm handshake. ... by taking advantage of citizenship via investment programs like ...
(Date:4/26/2016)... 27, 2016 Research and ... Biometrics Market 2016-2020"  report to their offering.  , ... The analysts forecast the global multimodal biometrics ... during the period 2016-2020.  Multimodal biometrics ... such as the healthcare, BFSI, transportation, automotive, and ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Sequenom, Inc. (NASDAQ: ... to enabling healthier lives through the development of innovative ... of the United States denied ... that the claims of Sequenom,s U.S. Patent No. 6,258,540 ... eligibility criteria established by the Supreme Court,s Mayo Collaborative ...
(Date:6/27/2016)... -- Liquid Biotech USA , Inc. ... Research Agreement with The University of Pennsylvania ("PENN") ... patients.  The funding will be used to assess ... outcomes in cancer patients undergoing a variety of ... to support the design of a therapeutic, decision-making ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Researchers at the ... commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject ... it now. , Diagnostic biomarkers are signposts in the blood, lung fluid or ...
(Date:6/23/2016)... 23, 2016 A person commits a crime, and ... to track the criminal down. An outbreak of ... Drug Administration (FDA) uses DNA evidence to track down the ... Sound far-fetched? It,s not. The FDA has increasingly used a ... of foodborne illnesses. Put as simply as possible, whole genome ...
Breaking Biology Technology: