Navigation Links
New imaging method sheds light on cell growth
Date:8/25/2011

CHAMPAIGN, Ill. University of Illinois researchers are giving a light answer to the heavy question of cell growth.

Led by electrical and computer engineering professor Gabriel Popescu, the research team developed a new imaging method called spatial light interference microscopy (SLIM) that can measure cell mass using two beams of light. Described in the Proceedings of the National Academy of Sciences, the SLIM technique offers new insight into the much-debated problem of whether cells grow at a constant rate or exponentially.

SLIM is extremely sensitive, quantitatively measuring mass with femtogram accuracy. By comparison, a micron-sized droplet of water weighs 1,000 femtograms. It can measure the growth of a single cell, and even mass transport within the cell. Yet, the technique is broadly applicable.

"A significant advantage over existing methods is that we can measure all types of cells bacteria, mammalian cells, adherent cells, nonadherent cells, single cells and populations," said Mustafa Mir, a graduate student and a first author of the paper. "And all this while maintaining the sensitivity and the quantitative information that we get."

Unlike most other cell-imaging techniques, SLIM a combination of phase-contrast microscopy and holography does not need staining or any other special preparation. Because it is completely non-invasive, the researchers can study cells as they go about their natural functions. It uses white light and can be combined with more traditional microscopy techniques, such as fluorescence, to monitor cells as they grow.

"We were able to combine more traditional methods with our method because this is just an add-on module to a commercial microscope," Mir said. "Biologists can use all their old tricks and just add our module on top."

Because of SLIM's sensitivity, the researchers could monitor cells' growth through different phases of the cell cycle. They found tha
'/>"/>

Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert  

Page: 1 2

Related biology news :

1. SNM releases new fact sheet on breast cancer and molecular imaging
2. Cheskin Added Value EVP Lee Shupp Discusses Evolving Dynamics of Consumers and Imaging Tech at 6Sight
3. MU brain imaging center provides research for autism, schizophrenia and Parkinsons disease
4. Similarities in imaging the human body, Earths crust focus of conference at UH
5. UNC expands brain imaging study of infants at risk for autism
6. Studies on imaging and tracking transplanted cells
7. Fattysaurus or thinnysaurus? How dinosaurs measure up with laser imaging
8. SNM Symposium on Multimodality Cardiovascular Molecular Imaging
9. Ultrasound imaging now possible with a smartphone
10. First neuroimaging study examining motor execution in children with autism reveals new insights
11. Lyncean Technologies Inc. receives $1.2 M from NCRR to develop new imaging technique
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New imaging method sheds light on cell growth
(Date:9/18/2014)... tonight at the third annual Golden Goose Award ceremony ... infants and in paving the way for the telecommunications ... by the National Science Foundation, the National Institutes of ... honored at a ceremony at the Library of Congress ... Congress will be on hand to help present their ...
(Date:9/18/2014)... are too stressed they are often grouchy, grumpy, nasty, ... (BMI) at EPFL have just highlighted a fundamental synaptic ... the loss of social skills and cognitive impairment. When ... molecule in the brain. This was revealed by a ... Carmen Sandi,s team went to look for answers in ...
(Date:9/18/2014)... their entire lives nestling in the protective tentacles of ... they sometimes travel hundreds of kilometres across the open ... fish has been predicted, this is the first time ... populations has been observed. , Dr Steve Simpson, Senior ... University of Exeter, and colleagues from the Australian Research ...
Breaking Biology News(10 mins):3rd annual Golden Goose award ceremony honors 8 researchers; Unusual work had big results 2How stress tears us apart 2Expedition finds Nemo can travel great distances to connect populations 2Expedition finds Nemo can travel great distances to connect populations 3
... the human gut adaptively shifts more than a quarter ... diet changes from sugar to complex carbohydrates. , This ... survive rapidly changing nutrient conditions but also helps maintain ... microbial society, according to researchers at Washington University School ...
... Inc. (Nasdaq: NGEN), developer of advanced diagnostic products, announced ... "Multiplexed Active Biologic Array" by the U.S. Patent and ... of addressing one or more electrodes (or "test sites") ... patent also covers a method for storing the value ...
... owners because of their vibrant colors. But those colors may ... For more than a century, biochemists have known that parrots ... of plumage colors, but their biochemical identity has remained elusive. ... behind the colors of parrots, describing on a molecular level ...
Cached Biology News:Highly adaptable genome in gut bacterium key to intestinal health 2Highly adaptable genome in gut bacterium key to intestinal health 3Nanogen Issued Patent for Electronic Microarray With Memory 2Transport System Smuggles Medicines Into Brain 2Transport System Smuggles Medicines Into Brain 3
(Date:9/19/2014)... Barnhardt Manufacturing Company has earned ... Organic Cotton . The USDA Certified Biobased Product Label ... meets or exceeds levels set by USDA. Biobased products ... in significant part of agricultural, forestry, or marine ingredients. ... to be immediately identified as a USDA certified BioPreferred ...
(Date:9/18/2014)... Bipartisan passage this week by the ... stimulate development and commercialization of new technologies and promote ... of SPIE, the international society for optics and ... Innovation (RAMI) Act, now moves to the full Senate ... are optimistic that it will win passage there as ...
(Date:9/18/2014)...  Health Enhancement Products, Inc. (OTCQB: HEPI), a ... and metabolic processes, is pleased to announce the addition of ... Nola E. Masterson , a California ... September 17, 2014. "We,re very pleased and ... states Andrew Dahl , President and CEO. "She joins ...
(Date:9/18/2014)... -- Research and Markets has announced ... Report 2014" report to their offering. ... is a professional and in-depth study on the ... The report provides a basic overview of ... chain structure. The N-acetylcysteine market analysis is provided ...
Breaking Biology Technology:Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2Global N-acetylcysteine Industry Report 2014 2
... LIBREVILLE, Gabon, December 2 ... Africa: Everyone,s Problem and Heritage" , ... June 2010 the,Gabonese Republic is hosting an international conference ... in Africa. The,conference will be attended by government and ...
... , ... an event bringing together the leaders in technology development ... announced the December 11th deadline for technology abstracts and ... World, in association with the Nano Science and Technology ...
... , SINGAPORE, Dec. 2 S*BIO Pte Ltd today ... at The American Society of Hematology 51st Annual Meeting and ... the clinical results from the Phase 1 dose-escalation trial of ... dose levels ranging from 100 to 600 mg. These doses ...
Cached Biology Technology:Libreville International Conference 2-3 June 2010 2Deadline Approaching for Largest Commercialization Event for Nanotech & Clean Technologies 2Deadline Approaching for Largest Commercialization Event for Nanotech & Clean Technologies 3S*BIO Novel Oral JAK2 Inhibitor SB1518 Demonstrates Safety and Tolerability in Phase 1 Studies for the Treatment of Myeloproliferative and Other Hematological Disorders 2S*BIO Novel Oral JAK2 Inhibitor SB1518 Demonstrates Safety and Tolerability in Phase 1 Studies for the Treatment of Myeloproliferative and Other Hematological Disorders 3S*BIO Novel Oral JAK2 Inhibitor SB1518 Demonstrates Safety and Tolerability in Phase 1 Studies for the Treatment of Myeloproliferative and Other Hematological Disorders 4S*BIO Novel Oral JAK2 Inhibitor SB1518 Demonstrates Safety and Tolerability in Phase 1 Studies for the Treatment of Myeloproliferative and Other Hematological Disorders 5
... Odyssey images are easily imported for data analysis , ... ... Extensive background and signal options to optimize, ... results , ...
... UltraPure Agarose and SYBR Safe DNA Gel Stain ... Saves money versus buying these same products separately ... alternative to ethidium bromide ... Agarose resolves DNA and RNA fragments from 100 bp ...
... E.Coli glycerol stocks contained in standard 96-well ... clones with approximately 5,000 clones per plate. ... plate well, the corresponding subplate is screened ... the positive well(s). Cells from a positive ...
... ml per liter of urine will give a ... BMD dipstick. ,Certification: The Donors are of ... to be NEGATIVE for HbsAg, HCV, HIV-1 & ... FDA methods. THIS MATERIAL IS SOLD FOR IN-VITRO ...
Biology Products: