Navigation Links
New hope for victims of stroke
Date:6/29/2010

A drug used to treat rheumatoid arthritis also reduces the damage a stroke inflicts on the brain according to lab research and preliminary findings from a clinical trial of stroke patients. The results open the door for a larger clinical study to refine the drug anakinra's use as an effective therapy for victims of stroke.

Top British neuroscientist Nancy Rothwell will summarise her team's latest research into both the causes of brain damage in stroke patients as well as future treatment options when she delivers The Physiological Society's annual public lecture on 30 June 2010.

Rothwell has just been appointed the new President and Vice-Chancellor of The University of Manchester where she has worked since 1987 making her the first woman to lead the University or either of its two predecessor institutions.

Rothwell's research group has been trying to find out what causes damage or death of brain cells in diseases such as stroke, brain injury, and Alzheimer's disease. They have discovered that a protein called interleukin-1 (IL-1) is an important "killer molecule" which is switched on after an insult to the brain. Rothwell's team have also shown that a naturally occurring blocker of IL-1 (called IL-1RA) reduces damage to the brain in experimental stroke. In commercial form, IL-1RA is currently produced as the drug anakinra and prescribed to sufferers of rheumatoid arthritis.

During every minute after a major stroke two million brain cells are lost, 14 billion connections are gone, and 7.5 miles of brain wiring destroyed.

"The brain is the most complicated structure that we know about," says Rothwell. "It houses billions of nerve cells and millions of kilometres of connections which allow us to move, breathe, think and remember. Even a small injury to part of the brain can be devastating, and brain diseases pose the greatest burden on society, affecting an increasing number of people and their families."

Str
'/>"/>

Contact: Mikaela Sitford
Mikaela.Sitford@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

Page: 1 2

Related biology news :

1. Stroke victims may benefit from stem cell transplants
2. Bamboo instant houses will soon shelter Sichuan quake victims
3. Cryopreservation techniques bring hopes for women cancer victims and endangered species
4. TGen, Scottsdale Healthcare, Mayo Clinic study new drug to stimulate immune system of cancer victims
5. Penn research team tests bedside monitoring of brain blood flow and metabolism in stroke victims
6. Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives
7. Blood pressure drug telmisartan shows powerful activity against stroke
8. Blueberry and green tea containing supplement protects against stroke damage
9. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
10. Can micro-scaffolding help stem cells rebuild the brain after stroke?
11. Tracking stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... spider toxins to study the proteins that let nerve ... they have stumbled upon a biological tactic that may ... plagues in a safe and environmentally responsible way. ... lethal for one species and harmless for a closely ... specific pests without harming beneficial species like bees. A ...
(Date:7/10/2014)... , June 27, 2014  Pomerantz LLP ... Biopharmaceuticals, Inc. ("Provectus" or the "Company")(NYSE-MKT: PVCT) and ... in United States District Court, Middle District of ... on behalf of a class consisting of all ... Provectus securities between December 17, 2013 and May ...
(Date:7/10/2014)... 2014 It is a great honor for ... of the world-renowned Thoracic and Cardiovascular surgeon, Mark E ... Dr. Ginsburg, with over 34 years of experience, is ... Good Samaritan Regional Medical Center. Dr. Ginsburg has been ... and is considered an expert in the implantation of ...
Breaking Biology News(10 mins):Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 3Avery Biomedical Devices, Inc. announces the appointment of Mark E Ginsburg, M.D. to its Board of Directors 2
... the blinding effects of diabetic retinopathy is pointing toward ... said. Interleukin-6, known to contribute to the ... inflammation of the retina, a first step in a ... working-age adults, MCG researchers reported online in Investigative ...
... Since the time of the earliest humans, people have ... our surroundings and searched for explanations for natural phenomena. ... questions remain to be answered. Although we understand core ... understanding of issues such as how plants maximize their photosynthetic ...
... SCOTTSDALE, Ariz. Jan. 13, 2010 Researchers ... have identified a way to predict which patients with ... The study, Tumor MicroRNA Biomarkers Associated with De ... presented today in San Diego at a joint conference ...
Cached Biology News:Discovery points toward anti-inflammation treatment for blinding disease 2Seeing the forest through the trees and seeing the trees through the leaves 2TGen-Scottsdale Healthcare researchers make breakthrough in lung cancer 2
(Date:7/11/2014)... July 11, 2014  Researchers have pioneered a ... The new technology, called Virtual Finger, allows scientists ... like neurons and synapses using the flat surface ... makes 3D imaging studies orders of magnitude more ... unprecedented level across many areas of experimental biology. ...
(Date:7/10/2014)... Understanding the need for better quality and ... gap that currently exists in this area, ChanTest has ... of validated ion channel and GPCR cell lines. ... ion channels control many critical physiological functions throughout the ... potential to treat a variety of human diseases. ...
(Date:7/10/2014)... July 10, 2014 EvoDerma ’s NOOME ... This rejuvenating device now comes with a second treatment cup ... time. , The new cup is thinner on the edges ... to target rough, thin and uneven surfaces on the face, ... for a stimulating treatment on areas such as the cheeks ...
(Date:7/10/2014)... , July 10, 2014 /PRNewswire-iReach/ -- Tute ... interpretation, today announced an agreement with Lineagen, ... for Lineagen,s NextStep Dx PLUS.  Lineagen, ... and neurological disorders, currently offers FirstStep Dx ... testing service used by healthcare providers as ...
Breaking Biology Technology:Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4
... production, announced today the appointment of Michael Bayer, MD, as Director, ... and clinical trial protocols for use by research centers conducting pre-clinical ... ... Diego, CA (PRWEB) January 30, 2009 -- Stemedica Cell Technologies ...
... of future electronic devices could shrink dramatically to one ... many tens of nanometers that characterize today,s most advanced elements ... walls, the ultrathin transition zones that separate regions of a ... , In a material called bismuth ferrite, an unusual compound ...
... this inaugural edition of the BBVA Foundation Frontiers of ... (Austria, 1952) and Ignacio Cirac (Manresa, 1965), "for their ... of the jury chaired by Theodor W. Hnsch, Nobel ... up vital new avenues for the development of quantum ...
Cached Biology Technology:Stemedica Announces the Appointment of Dr. Michael Bayer as Director, Medical Services 2Stemedica Announces the Appointment of Dr. Michael Bayer as Director, Medical Services 3Domain walls that conduct electricity 2Domain walls that conduct electricity 3Domain walls that conduct electricity 4Domain walls that conduct electricity 5Peter Zoller and Ignacio Cirac, awarded by the BBVA Foundation 2
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/L; 1 tube of 1, 000 units enzyme/tube w/Buffer II and MgCl2...
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/uL; 25 tubes of 1, 000 units enzyme/tube w/ Buffer I...
A robust formulation of Taq Polymerase supplied with a 10X colored reaction buffer which allows Direct Gel-Loading...
Ps-Aeruginosa (IgA) -Ab EIA Sample Size: 100 l...
Biology Products: