Navigation Links
New hope for victims of stroke
Date:6/29/2010

A drug used to treat rheumatoid arthritis also reduces the damage a stroke inflicts on the brain according to lab research and preliminary findings from a clinical trial of stroke patients. The results open the door for a larger clinical study to refine the drug anakinra's use as an effective therapy for victims of stroke.

Top British neuroscientist Nancy Rothwell will summarise her team's latest research into both the causes of brain damage in stroke patients as well as future treatment options when she delivers The Physiological Society's annual public lecture on 30 June 2010.

Rothwell has just been appointed the new President and Vice-Chancellor of The University of Manchester where she has worked since 1987 making her the first woman to lead the University or either of its two predecessor institutions.

Rothwell's research group has been trying to find out what causes damage or death of brain cells in diseases such as stroke, brain injury, and Alzheimer's disease. They have discovered that a protein called interleukin-1 (IL-1) is an important "killer molecule" which is switched on after an insult to the brain. Rothwell's team have also shown that a naturally occurring blocker of IL-1 (called IL-1RA) reduces damage to the brain in experimental stroke. In commercial form, IL-1RA is currently produced as the drug anakinra and prescribed to sufferers of rheumatoid arthritis.

During every minute after a major stroke two million brain cells are lost, 14 billion connections are gone, and 7.5 miles of brain wiring destroyed.

"The brain is the most complicated structure that we know about," says Rothwell. "It houses billions of nerve cells and millions of kilometres of connections which allow us to move, breathe, think and remember. Even a small injury to part of the brain can be devastating, and brain diseases pose the greatest burden on society, affecting an increasing number of people and their families."

Stroke is the third most common cause of death in England and Wales. It's estimated that 150,000 people have a stroke in the UK each year and there are over 300,000 people in England living with significant disability as the result of a stroke.

Rothwell's talk entitled 'Tracking Down Killers in the Brain' is the public lecture for The Physiological Society's main meeting 'Physiology 2010'. The Physiological Society is a learned scientific society and registered charity which seeks to promote and support the study of physiology around the world. Each year at their main scientific conference the Society holds a public lecture designed to illustrate the importance of physiology and further its understanding by the general public and in schools.


'/>"/>

Contact: Mikaela Sitford
Mikaela.Sitford@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

Related biology news :

1. Stroke victims may benefit from stem cell transplants
2. Bamboo instant houses will soon shelter Sichuan quake victims
3. Cryopreservation techniques bring hopes for women cancer victims and endangered species
4. TGen, Scottsdale Healthcare, Mayo Clinic study new drug to stimulate immune system of cancer victims
5. Penn research team tests bedside monitoring of brain blood flow and metabolism in stroke victims
6. Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives
7. Blood pressure drug telmisartan shows powerful activity against stroke
8. Blueberry and green tea containing supplement protects against stroke damage
9. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
10. Can micro-scaffolding help stem cells rebuild the brain after stroke?
11. Tracking stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/21/2016)... 2016 Unique technology combines ... superior security   Xura, Inc. ... secure digital communications services, today announced it is working ... enterprise customers, particularly those in the Financial Services Sector, ... authentication within a mobile app, alongside, and in combination ...
(Date:3/17/2016)... 17, 2016 ABI Research, the leader ... global biometrics market will reach more than $30 ... from 2015. Consumer electronics, particularly smartphones, continue to ... anticipated to reach two billion shipments by 2021 ... Pavlakis , Research Analyst at ABI Research. "Surveillance ...
(Date:3/15/2016)... , March 15, 2016 Yissum Research ... the technology-transfer company of the Hebrew University, announced today ... remote sensing technology of various human biological indicators. Neteera ... $2.0 million from private investors. ... on the detection of electromagnetic emissions from sweat ducts, ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... ... April 29, 2016 , ... During ... transform technology into a viable company, CereScan’s CEO, John Kelley, joined other Denver ... recognized leader and mentor in the Denver area business community, shared his top ...
(Date:4/29/2016)... -- Elekta is pleased to announce that ... treatment planning software, is available for clinical release. Real-world ... version 5.11 provides significant performance speed enhancements over prior ... four times faster than in previous versions of ... Monte Carlo algorithm, users can ...
(Date:4/28/2016)... Conn. (PRWEB) , ... April 28, 2016 , ... ... financing and ongoing support for Connecticut's innovative, growing companies, today announced the launch ... health and financial technology (fintech) companies. , “VentureClash looks to attract ...
(Date:4/28/2016)... ... April 28, 2016 , ... ... hold an open house for regional manufacturers at its Maple Grove, Minnesota technical ... Okuma, Hardinge Group, Chiron and Trumpf. Almost 20 leading suppliers of tooling, ...
Breaking Biology Technology: