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New genetic testing technology for IVF embryos
Date:5/23/2011

detect two different kinds of genetic alterations while causing minimal harm to the embryo, but also in the speed with which it can be completed," says Kearns. "This allows the embryo to be transferred back into the mother in a timely manner."

Since the online publication of this study in December 2010, Kearns, who also directs the Shady Grove Center for Preimplantation Genetics in Rockville, MD, has offered combined PGD and aneuploidy testing to seven more couples. Five of these seven couples have achieved pregnancy with this technique and one couple is scheduled to transfer an embryo in the near future. Speaking of one of the couples, he says, "I am really happy for this couple. She is a 39-year-old woman who is a carrier for Fragile X syndrome (a genetic disease that causes mental disabilities) and had two first trimester miscarriages. We did the same methodology on her and now she is pregnant. It is spectacular."

And they aren't stopping there. Kearns and Brezina are trying to further improve existing technologies so that they can more accurately identify genetic abnormalities in IVF embryos. "IVF is only going to become more relevant as time goes on and as it gets better and better," says Brezina. He adds "The ability to know detailed information about the embryos you are putting back in, it is a powerful thing."


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Contact: John Lazarou
jlazaro1@jhmi.edu
410-502-8902
Johns Hopkins Medical Institutions
Source:Eurekalert

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