Navigation Links
New gel to promote bone growth on implants used in surgical procedures
Date:3/30/2014

A research group at Uppsala University, Sweden has developed a new responsive coating for implants used in surgery to improve their integration into bone and to prevent rejection. Neutron scattering experiments at the Institut Laue-Langevin (ILL) in Grenoble, France have shown how a protein that promotes bone growth binds to this surface and can be released in a controlled way.

Orthopaedic and dental implants must last for many years. Success for these surgical components depends on integration into adjacent bone tissue. Gels made by modifying hyaluronan, a large biological molecule, can be used to coat implants. A new paper in Advanced Engineering Materials shows that the coated titanium surfaces can bind protein molecules which promote bone formation. These can be released slowly once the surface comes in contact with a solution of calcium ions. This process would stimulate the growth of bone on the implant.

The gel layers, a few millionths of a millimetre thick, were characterised using neutron reflection at the ILL, a technique that provides a detailed picture of what happens at a surface. In their new paper the research team showed that the protein, BMP-2, that encourages bone growth was bound to the gel. They also demonstrated that the layer of protein was stable in water but could be released slowly by adding solutions containing calcium, a process that was observed in real time using neutron reflection to track the amount of protein at the surface.

The research group has now launched trials of similar materials for metal implants in rabbits. These ongoing studies are made in collaboration with the Swedish Agricultural University in Uppsala and they provide a step towards transfer of the results to clinical applications.

'Interdisciplinary research and partnerships allow advanced analytical tools to be applied to important but difficult medical and scientific challenges. This exciting work comes from
'/>"/>

Contact: Adrian Rennie
Adrian.Rennie@physics.uu.se
46-070-425-0914
Uppsala University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Tracking neighborhood eating habits to promote healthier diets
2. An innovative approach to promote water use efficiency
3. First-ever book on Mekong rattan species aims to promote sustainable practices
4. Manga comics may help promote fruit consumption among youth
5. Large amounts of folic acid shown to promote growth of breast cancer in rats
6. Neurotransmitters resarch can promote better drugs for brain disorders
7. Mannotriose promotes survival of hippocampal neurons
8. Gene promotes 1 in 100 of tumors
9. New research shows tea may help promote weight loss, improve heart health and slow progression of prostate cancer
10. Treadmill step training promotes motor function after incomplete spinal cord injury
11. Dysfunctional chemokine receptor promotes candidiasis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New gel to promote bone growth on implants used in surgical procedures
(Date:7/21/2015)... 21, 2015 Passwords have proven futile ... the recent U.S. Office of Personnel Management breach. ... infosec conundrum, but developers and end-users are concerned ... this dilemma, Biometrics-as-a-Service provider HYPR Corp. announced today ... for third party integration. A ...
(Date:7/9/2015)... , July 9, 2015  Synaptics Inc. (NASDAQ: ... announced today that it will report financial results for ... July 30, 2015 after the close of market. The ... and investors at 2:00 p.m. PT (5:00 p.m. ET), ... To participate on the live call, analysts and ...
(Date:7/8/2015)... NEW YORK , July 8, 2015 ... cancer globally, and the fourth most fatal, with a ... year. The poor prognosis of pancreatic cancer patients has ... to treatment, which is not being met by the ... contains an array of products with varying molecule types ...
Breaking Biology News(10 mins):HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3
... The tendency toward obesity is directly related to the brain ... according to a new study. Researchers at Tufts University School ... a predisposition to obesity and defective dopamine signaling in the ... 2008 issue of The FASEB Journal . ...
... 2008) -- In a first, scientists from Weill Cornell ... the specifics of how brain cells process antidepressant drugs, ... in the development of more targeted medication therapies for ... area of addiction. Their breakthrough research, featured as ...
... record biometric revenues and profitability, WALL, N.J., ... BKYI), a leader in wireless public safety and,finger-based ... and strong revenue growth for its second quarter,ended ... operations for the quarter ended June 30,2008 was ...
Cached Biology News:Obesity predisposition traced to the brain's reward system 2Obesity predisposition traced to the brain's reward system 3N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets 2N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets 3BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 2BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 3BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 4BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 5
(Date:7/31/2015)... ... July 31, 2015 , ... ... and quantification of partially hydrolyzed gluten in foods, has been accepted by AOAC ... method “Partially Hydrolyzed Gluten in Fermented Cereal-Based Products by R5 Competitive ELISA,” based ...
(Date:7/30/2015)... ... July 30, 2015 , ... The 2015 Market Research Report on ... current state of the global Propanol market with a focus on the Chinese situation. ... Carboclor, Mitsui Chemicals, Oxea, ISU Chemical, Sanofi, Royal Dutch Shell, LG Chem and Zhejiang ...
(Date:7/30/2015)... , July 30, 2015  With over 60,000 customers across the globe, ISN ... connect 450 hiring organizations with more than 60,000 safe and reliable contractors in over 80 countries. ... ... ... Headquartered in Dallas, TX ...
(Date:7/30/2015)... NH (PRWEB) , ... July 30, 2015 , ... ... homogenizer for advanced fluid applications and designed for continuous operation up to 1500 ... and sterilization-in-place, ensuring safety, efficiency, and preventing toxic contamination. , The Pony™ NS2006L ...
Breaking Biology Technology:RIDASCREEN® Competitve Gliadin Receives AOAC Official First Action Status 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 3ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2
... Medical College of Wisconsin is reuniting the commissioners, ... document that laid the ethical foundation for human research ... the reports completion in 1979, the Belmonters will come ... its enduring impact on research and celebrate its 25th ...
... know who signs the paychecks in your organization. Most of ... reports to whom. We might even know one or two ... tell you much about who your IT staff is really ... staff members become moles in your organization as they further ...
... its formation based on technology licensed from the ... will be using the patented technology for an industrial ... of RmSys indicated the company has secured a license ... technology. , ,CATI Director Matthew Wagner said the ...
Cached Biology Technology:Belmont Report Commission reuniting for Medical College of Wisconsin Symposium 2Who does your IT staff work for? 2Who does your IT staff work for? 3
Caveolin Sampler Kit 10g each...
Slide Chambers are convenient for performing pre-hybridization incubations and post-hybridization washes with tissue sections mounted on standard glass microscope slides. Each chamber holds up to 5 s...
Cord blood endothelial progenitor cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood Progenitor Cells...
Umbilical cord blood basophils, For immunohistochemistry (IHC)...
Biology Products: