Navigation Links
New gel to promote bone growth on implants used in surgical procedures
Date:3/30/2014

A research group at Uppsala University, Sweden has developed a new responsive coating for implants used in surgery to improve their integration into bone and to prevent rejection. Neutron scattering experiments at the Institut Laue-Langevin (ILL) in Grenoble, France have shown how a protein that promotes bone growth binds to this surface and can be released in a controlled way.

Orthopaedic and dental implants must last for many years. Success for these surgical components depends on integration into adjacent bone tissue. Gels made by modifying hyaluronan, a large biological molecule, can be used to coat implants. A new paper in Advanced Engineering Materials shows that the coated titanium surfaces can bind protein molecules which promote bone formation. These can be released slowly once the surface comes in contact with a solution of calcium ions. This process would stimulate the growth of bone on the implant.

The gel layers, a few millionths of a millimetre thick, were characterised using neutron reflection at the ILL, a technique that provides a detailed picture of what happens at a surface. In their new paper the research team showed that the protein, BMP-2, that encourages bone growth was bound to the gel. They also demonstrated that the layer of protein was stable in water but could be released slowly by adding solutions containing calcium, a process that was observed in real time using neutron reflection to track the amount of protein at the surface.

The research group has now launched trials of similar materials for metal implants in rabbits. These ongoing studies are made in collaboration with the Swedish Agricultural University in Uppsala and they provide a step towards transfer of the results to clinical applications.

'Interdisciplinary research and partnerships allow advanced analytical tools to be applied to important but difficult medical and scientific challenges. This exciting work comes from
'/>"/>

Contact: Adrian Rennie
Adrian.Rennie@physics.uu.se
46-070-425-0914
Uppsala University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Tracking neighborhood eating habits to promote healthier diets
2. An innovative approach to promote water use efficiency
3. First-ever book on Mekong rattan species aims to promote sustainable practices
4. Manga comics may help promote fruit consumption among youth
5. Large amounts of folic acid shown to promote growth of breast cancer in rats
6. Neurotransmitters resarch can promote better drugs for brain disorders
7. Mannotriose promotes survival of hippocampal neurons
8. Gene promotes 1 in 100 of tumors
9. New research shows tea may help promote weight loss, improve heart health and slow progression of prostate cancer
10. Treadmill step training promotes motor function after incomplete spinal cord injury
11. Dysfunctional chemokine receptor promotes candidiasis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New gel to promote bone growth on implants used in surgical procedures
(Date:7/22/2014)... recent scientific discovery showed that mutations in prickle ... brain disorder characterized by repeated seizures over time. ... was unknown. , A new University of Iowa ... Proceedings of the National Academy of Sciences , ... epilepsy. UI researchers have identified the basic cellular ...
(Date:7/22/2014)... The Carlton Complex fires started on July 14, 2014, by ... Valley. The Carlton Complex consists of four fires: Stokes Fire, ... The Stokes and Gold Hikes fires are now one larger ... the area burning is currently over 243,000 acres in size. ... to the high fire danger. Public and firefighter safety is ...
(Date:7/22/2014)... known as the ,1000 Bull Genomes Project, aims to ... cattle while also improving animal health and welfare. Results ... the whole genomes of 234 individual bulls whose direct ... reported in the journal Nature Genetics . , ... information to reduce or eliminate hereditary diseases and to ...
Breaking Biology News(10 mins):UI study finds potential genetic link between epilepsy and neurodegenerative disorders 2Whole-genome sequencing of bulls in key beef and dairy breeds 2
... Researchers at Delft University of Technology and the ... provides a unique test and measurement platform for the ... the journal Nature Nanotechnology (June 19 - ... with key proteins which mimicks the natural nuclear pore. ...
... pointed to a collection of test tubes in her Iowa ... like they were holding very weak coffee. That meant microorganisms ... biochemically converting sugars into hydrocarbons, said Jarboe, an Iowa State ... of the sugars in those test tubes were produced by ...
... prolonged snowfall can bring about unexpected conditions that encourage fungal ... according to experts. A new international study confirms that ... grow bigger, heavy and prolonged snow can, in certain circumstances, ... strains. The research results, published in the journal ...
Cached Biology News:Mimicking nature at the nanoscale: Selective transport across a biomimetic nanopore 2Iowa State hybrid lab combines technologies to make biorenewable fuels and products 2Iowa State hybrid lab combines technologies to make biorenewable fuels and products 3Arctic snow harbors deadly assassin 2
(Date:7/22/2014)... Sunnyvale, CA (PRWEB) July 22, 2014 ... begin on September 9th, 2014 and will comprise of ... and Application’ classes. The TechTrainings is a series of ... professionals, designed to help them reach the next step ... SAS class is taught by Jennifer Kang, Senior ...
(Date:7/21/2014)... Vernon Hills, IL (PRWEB) July 21, 2014 ... remote control, and simple programming, the new ... Pump Head is easy to operate for ... between cycles for hands-free dispensing. The batch count ... the cumulative volume or totalizer tracks amount dispensed ...
(Date:7/21/2014)... yield so far is small, but chemists at the ... substitution process to make a precursor to transparent thin ... energy devices. , A paper describing the approach is ... of the journal Inorganic Chemistry , which draws ... nuclear chemistry fields. The paper was chosen by the ...
(Date:7/21/2014)... Sleep disturbances such as insomnia, hypersomnia, ... depression. According to a study published by the ... of depressed patients have insomnia symptoms, and hypersomnia ... adults and 10% of older patients, with a ... have a major impact on quality of life, ...
Breaking Biology Technology:Clinovo TechTrainings: Next Session of SAS and CDISC Classes Start 9th September, 2014 2Clinovo TechTrainings: Next Session of SAS and CDISC Classes Start 9th September, 2014 3New Easy-View Cole-Parmer Digital Gear Pump Drive Makes Performance Monitoring Effortless 2Oregon chemists eye improved thin films with metal substitution 2Open Label Data on Enhanced Sleep Released by JayMac Pharmaceuticals, LLC 2Open Label Data on Enhanced Sleep Released by JayMac Pharmaceuticals, LLC 3
... — As a former attorney and current managing director ... certainly has tackled his share of challenges. But the ... its Public Advisory Committee, for which he recently began ... intimidated. , ,"I have to tell you, it's a ...
... Morlino has been elected chairman of the board of ... as stem-cell research. , , Morlino told The Capital ... human embryo is always morally wrong, and that research ... stem-cell research involves taking the cells initially from embryos, ...
... for a month-long series of events at the University ... in the Engineering Centers Building on April ... and three "science spectaculars", all free, non-ticketed, and open ... ,"It's a big sort of circus of science, basically," ...
Cached Biology Technology:Gulbrandsen tackles 'daunting' challenges in Patent Office 2Madison bishop with stem-cell views elected to national ethics group 2UW show to give public a go at cutting-edge science 2
... is an evolutionarily conserved form of cell ... The central component of this process ... caspases. These enzymes participate in a ... response to pro-apoptotic signals and result in ...
... DNA Visualizer Extraction Kit is manufactured for ... DNA damage byexposure to UV light. The ... is often used for DNA-cloning work. The ... bromide and exposure of UV light damages ...
... TargeTron(TM) Gene Knockout System provides optimized reagents ... disruption of bacterial genes by insertion of ... retrohoming ability of group II introns and ... the TargeTron group II intron for specific ...
Mouse monoclonal antibody raised against a partial recombinant VRK2. NCBI Entrez Gene ID = VRK2...
Biology Products: