Navigation Links
New formula invented for microscope viewing, substitutes for federally controlled drug
Date:5/17/2013

Researchers at Rutgers, The State University of New Jersey, and City University of New York have invented a proprietary new formulation called VisikolTM that effectively clears organisms to be viewed under microscopes. Visikol can be used in place of chloral hydrate, which is one of the few high-quality clearing solutions currently available but which is tightly regulated by the Drug Enforcement Administration (DEA) due to its use as a narcotic.

Clearing solutions, or clearing agents, are vital for viewing organisms under a microscope. Without them, microscope images become refracted and scattered, impairing the clarity of vision. Clearing solutions are used to identify specimens and examine their anatomy by "clearing" them, increasing the transparency of the specimen by rendering some components of a specimen invisible in order to better view other components of interest.

One of the most common clearing solutions is chloral hydrate, which is used for everything from studying plant organelles to authenticating herbal plant species for medicinal purposes. Its popularity in the research community, government, and industry stems from its high refractive index, which allows a high magnitude of light to pass through the medium and make specimens crystal clear under the microscope.

However, chloral hydrate is difficult and expensive to obtain, as it is regulated by the DEA as a Schedule IV controlled substance. Chloral hydrate is prescribed medically as a sedative, depressant, pain reliever, and hypnotic, and overdoses can lead to serious health issues, including fatal heart conditions. Chloral hydrate has also found use as an illicit drug, and has been used in sexual assaults. Thus, possession of chloral hydrate requires costly, annual permits and time-consuming paperwork. Despite its advantages for research and industry, chloral hydrate is an impractical, and sometimes impossible, choice for scientists.

To replace c
'/>"/>

Contact: Beth Parada
apps@botany.org
American Journal of Botany
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study shows botanical formula fights prostate cancer
2. Reduced glycerin formulation of tenofovir vaginal gel safe for rectal use
3. Hazelnuts improve infant formula
4. Liquid glucagon formulation discovered for potential use in artificial pancreas systems
5. Maths formula leads researchers to source of pollution
6. Breast milk promotes a different gut flora growth than infant formulas
7. UC Riverside developing biofuel formulations for California
8. New, cost-cutting approach to formulating pest-killing fungi
9. Human eye inspires clog-free ink jet printer invented by MU researcher
10. Beyond the microscope: Identifying specific cancers using molecular analysis
11. Nature: Microscope looks into cells of living fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... to tetrachloroethylene (PCE) in drinking water may increase ... to a new study led by a Boston ... study, published in the journal Environmental Health ... pregnancies among 1,766 women in Cape Cod, Ma., ... to the early 1980s by the installation of ...
(Date:9/30/2014)... live in almost any aquatic environment on Earth, but ... species are pushed to the limit. The amount of ... critical for how different species cope in the future, ... of Gothenburg, published in the scientific journal Proceedings ... continues apace thanks to increasing levels of greenhouse gases ...
(Date:9/30/2014)... and farm runoff in Hawaii is causing tumors in ... The study, published Tuesday in the peer-reviewed open-access journal ... ends up in algae that the turtles eat, promoting ... and internal organs. , Scientists at Duke University, the ... Administration (NOAA) conducted the study to better understand the ...
Breaking Biology News(10 mins):Contaminated water linked to pregnancy complications, BU study finds 2Shape up quickly -- applies to fish, too! 2Pollution linked to lethal sea turtle tumors 2Pollution linked to lethal sea turtle tumors 3
... is available in German . , What is ... what do they mean for the nutrition and balance of a ... growing data streams even in mobile internet access? How do the ... this view imply for the interpretation of artistic creations in general? ...
... Singapore, May 9, 2012 Researchers at the ... bioengineering and nanotechnology research institute, have developed a miniaturized ... stem cells (CSCs). Published recently in Nano Today ... more effective cancer drugs. In a tumor, CSCs ...
... on behalf of the European Pet Food Industry Federation ... A consumption for puppies. The research marks a significant ... vitamin A levels for puppies and sheds new light ... was conducted by scientists from the Free University of ...
Cached Biology News:DFG establishes 10 new priority programs 2DFG establishes 10 new priority programs 3IBN's Droplet Array sheds light on drug-resistant cancer stem cells 2IBN's Droplet Array sheds light on drug-resistant cancer stem cells 3Collaborative research team identifies safe upper level for vitamin A consumption for puppies 2
(Date:9/30/2014)... 2014 Rainbow Scientific, Inc. (RSI), ... recently opened an online store to add customer ... lines developed and manufactured by Biological Industries, Inc. ... Biological Industries’ Nutristem® serum-free, xeno-free reagents for human ... cell (hESC) culture. , The online store ...
(Date:9/30/2014)... Whitehouse, New Jersey (PRWEB) September 30, 2014 ... that it has been chosen by the Parenteral ... course (November 18 and 19, 2014) on container closure ... current container closure integrity test methods and philosophies detailed ... Product – Integrity Evaluation. The course will ...
(Date:9/29/2014)... (PRWEB) September 30, 2014 Each ... burn injuries require medical attention. In the military, ... serious complications to battlefield medical care. More than ... and Afghanistan. Burn wounds heal slowly, remain inflamed ... be excessive, physically debilitating and functionally damaging. While ...
(Date:9/29/2014)... Sept. 29, 2014  Ten of the most ... cartilage repair, regeneration, allograft reconstruction and research and ... world gathered to discuss the future of cartilage ... Regenerative Medicine symposium, Cartilage Regeneration: State of ... Orthopedic Biosurgery, Minced Juvenile Allograft, and State of ...
Breaking Biology Technology:Rainbow Scientific, Inc. opens online store for state-of-the-art stem cell culture and cytogenetic reagents 2Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 2Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 3Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 4Faster Healing with Fewer Scars 2World Renowned Experts Discuss Future Of Cartilage Regeneration 2World Renowned Experts Discuss Future Of Cartilage Regeneration 3
... , DeKalb, Ill. Scientists at Northern Illinois University ... high yields of graphene, a highly touted carbon nanostructure ... fabric of the future. The focus of intense ... material, comprised of a single layer of carbon atoms ...
... Netsmart Technologies, Inc. ( www.ntst.com ... for health and human services organizations, today announced ... software for behavioral health provider organizations has achieved ... (Logo: http://photos.prnewswire.com/prnh/20110620/NY22778LOGO) "We are fully committed ...
... Neogen Corporation (NASDAQ: NEOG ) announced today ... seafood testing laboratory from its parent company, GlycoMar Ltd. ... services to the shellfish and salmon aquaculture industries. VeroMara,s ... including E. coli , noroviruses, and salmon husbandry. ...
Cached Biology Technology:Northern Illinois University scientists find simple way to produce graphene 2CMHC/MIS Electronic Health Record Solution from Netsmart Technologies Attains Complete ARRA Certification 2CMHC/MIS Electronic Health Record Solution from Netsmart Technologies Attains Complete ARRA Certification 3CMHC/MIS Electronic Health Record Solution from Netsmart Technologies Attains Complete ARRA Certification 4Neogen Acquires VeroMara from GlycoMar Ltd. 2
Bovine Coronary Artery Smooth Muscle Cells (BCASMC) (>500,000 cells)...
Bovine Pulmonary Artery Endothelial Cells (BPAEC) (>500,000 cells)...
Bovine Aortic Smooth Muscle Cells (BAOSMC) (>500,000 cells)...
Bovine Brain Microvascular Endothelial Cells (BBMVEC) (>500,000 cells)...
Biology Products: