Navigation Links
New food allergy model for fenugreek developed

A mouse model to investigate allergy to fenugreek has been developed by Norwegian researchers. The model can also be used to study cross-reactivity to peanut, soy and lupin, major food allergens with public health relevance.

Fenugreek is a member of the legume family and is used as an ingredient in curries, chutneys and teas. Allergic reactions to fenugreek may be severe yet its presence is rarely declared in ingredient listings. There is also great concern about potential cross-reactivity with other legumes such as peanut, soy and lupin.

"Allergens that are hidden in generic terms like spices, pose a special problem for food-allergic people. Fenugreek is a well-known food ingredient in Asian dishes, and as dietary patterns are changing, we will be more exposed to fenugreek also in Norway. Mouse models are important research tools that give valuable information in the understanding of food allergies, and may contribute to develop specific therapies for these food allergies" says Nina Eriksen Vinje, researcher at the Division of Environmental Medicine at the Norwegian Institute of Public Health and first author of the paper published in the Scandinavian Journal of Immunology.

Cross-reactivity between peanut and fenugreek first came to attention in 2006. The Norwegian Food Allergy Register received reports about allergic reactions to food containing curry powder, and cross-reactivity between peanut and fenugreek was confirmed in two peanut-allergic patients. It has since been discovered that fenugreek gives a stronger cross-reaction to peanut than other legumes such as soy and green peas.

Mouse models

New foods need to be tested on specific food-allergy models for each potential allergen. Mice are used as they have a well-characterised immune system that resembles the human immune system, allowing researchers to study complex immune reactions. The food-allergy model for fenugreek developed by the Norwegian Institute of Public Health can also be used to understand suspected cross-reactivity to peanuts and other legumes.


Contact: Julie Johansen
Norwegian Institute of Public Health

Related biology news :

1. Expert recommends town councils to design low-allergy impact green spaces
2. Lab test for allergy scoops national
3. Scientists developing food allergy treatment
4. REGiMMUNE receives $12 million in grants to develop transplant and allergy drugs
5. New discovery may lead to new class of allergy drugs
6. Malfunction of the respiratory epithelium is a cause of allergy?
7. Allergy season: Cigarettes to the rescue?
8. Yale team identifies key to potential new treatment for allergy-induced asthma
9. Nutricia launches Nutra Neocate, weaning product designed for cows’ milk protein allergy
10. EPA grant to University of Chicago for research on food allergy triggers
11. Common allergy drug reduces obesity and diabetes in mice
Post Your Comments:
(Date:11/18/2015)... New York , November 18, 2015 ... Market Research has published a new market report titled ... Growth, Trends, and Forecast, 2015 - 2021. According to the ... in 2014 and is anticipated to reach US$29.1 bn ... to 2021. North America ...
(Date:11/16/2015)... Calif. , Nov 16, 2015  Synaptics ... of human interface solutions, today announced expansion of ... TouchView ™ touch controller and display driver ... revolution of smartphones. These new TDDI products add ... TD4100 (HD resolution), TD4302 (WQHD resolution), and TD4322 ...
(Date:11/10/2015)... LONDON , Nov. 10, 2015 /PRNewswire/ ... segmented on the basis of product, type, ... segments included in this report are consumables, ... this report are safety biomarkers, efficacy biomarkers, ... in this report are diagnostics development, drug ...
Breaking Biology News(10 mins):
(Date:11/24/2015)...  Clintrax Global, Inc., a worldwide provider of clinical research services ... that the company has set a new quarterly earnings record in ... growth posted for Q3 of 2014 to Q3 of 2015.   ... , with the establishment of an Asia-Pacific ... United Kingdom and Mexico , ...
(Date:11/24/2015)... ... 2015 , ... This fall, global software solutions leader SAP and AdVenture Capital ... and pitch their BIG ideas to improve health and wellness in their schools. , ... win the title of SAP's Teen Innovator, an all-expenses paid trip to Super Bowl ...
(Date:11/24/2015)... Massachusetts , November 24, 2015 SHPG ... will participate in the Piper Jaffray 27 th Annual Healthcare ... Tuesday, December 1, 2015, at 8:30 a.m. EST (1:30 p.m. GMT). ... , Chief Financial Officer, will participate in the Piper Jaffray 27 ... , NY on Tuesday, December 1, 2015, at 8:30 a.m. ...
(Date:11/24/2015)... -- Tikcro Technologies Ltd. (OTCQB: TIKRF) today announced that its Annual General Meeting ... Israel time, at the law offices of ... th Floor, Tel Aviv, Israel . ... Izhak Tamir to the Board of Directors; , election of ... approval of an amendment to certain terms of options granted to our ...
Breaking Biology Technology: