Navigation Links
New evidence shows how chronic stress predisposes brain to mental disorders
Date:2/11/2014

the journal Molecular Psychiatry.

Does stress affect brain connectivity?

Kaufer's findings suggest a mechanism that may explain some changes in brain connectivity in people with PTSD, for example. One can imagine, she said, that PTSD patients could develop a stronger connectivity between the hippocampus and the amygdala the seat of the brain's fight or flight response and lower than normal connectivity between the hippocampus and prefrontal cortex, which moderates our responses.

"You can imagine that if your amygdala and hippocampus are better connected, that could mean that your fear responses are much quicker, which is something you see in stress survivors," she said. "On the other hand, if your connections are not so good to the prefrontal cortex, your ability to shut down responses is impaired. So, when you are in a stressful situation, the inhibitory pathways from the prefrontal cortex telling you not to get stressed don't work as well as the amygdala shouting to the hippocampus, 'This is terrible!' You have a much bigger response than you should."

She is involved in a study to test this hypothesis in PTSD patients, and continues to study brain changes in rodents subjected to chronic stress or to adverse environments in early life.

Stress tweaks stem cells

Kaufer's lab, which conducts research on the molecular and cellular effects of acute and chronic stress, focused in this study on neural stem cells in the hippocampus of the brains of adult rats. These stem cells were previously thought to mature only into neurons or a type of glial cell called an astrocyte. The researchers found, however, that chronic stress also made stem cells in the hippocampus mature into another type of glial cell called an oligodendrocyte, which produces the myelin that sheaths nerve cells.

The finding, which they demonstrated in rats and cultured rat brain cells, suggests a key role for oligodendro
'/>"/>

Contact: Robert Sanders
rlsanders@berkeley.edu
510-643-6998
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Study suggests whole diet approach to lower CV risk has more evidence than low-fat diets
2. Evidence of harmful effect of bisphenol A-based plastics
3. Blind cavefish offer evidence for alternative mechanism of evolutionary change
4. CU-Boulder-led team finds first evidence of primates regularly sleeping in caves
5. New evidence suggests Neanderthals organized their living spaces
6. Evidence of 3.5 billion-year-old bacterial ecosystems found in Australia
7. No evidence to support stem cell therapy for pediatric optic nerve hypoplasia
8. New evidence that cancer cells change while moving throughout body
9. Exploring the Latest Evidence of Dairys Contribution to Nutrition at IUNS Satellite Symposium
10. New evidence for warm-blooded dinosaurs
11. Evidence suggests Antarctic crabs could be native
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New evidence shows how chronic stress predisposes brain to mental disorders
(Date:3/20/2015)... Mar. 20, 2015 Research and Markets ... of the "India Sensors Market Forecast and ... The sensor market is projected to grow ... Consumer electronics, automotive, industrial and healthcare sectors ... the country. In addition, adoption of MEMS technology ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/vkzvcs/iris_biometrics ) has ... Strategic Business Report" report to their offering. ... US$ Thousands. The report provides separate comprehensive analytics for the ... , Europe , Asia-Pacific ... Latin America . Annual estimates and forecasts ...
(Date:3/17/2015)... Minn. , March 17, 2015 ... technology company specializing in clinical study management systems, ... be in attendance at ARENA,s Outsourcing in Clinical ... NC.  This event provides an excellent forum for ... easy-to-use, flexible and affordable software-as-a-service (SaaS) eClinical technology ...
Breaking Biology News(10 mins):India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2
... biodiversity bounty in the Eastern Pacific—approximately 50 percent of ... science. The research team spent 11 days in the ... of Panama. , Coordinated by Rachel Collin ... Smithsonian scientists and international collaborators with expertise in snails, ...
... people, the immune system turns against parts of the ... disease. Now, researchers at the National Institutes of Health's ... Diseases (NIAMS), in collaboration with the Oklahoma Medical Research ... factor: the early development of immune system cells called ...
... neuroscience is having an impact on computer science and ... Tomaso Poggio's laboratory at the McGovern Institute for Brain ... the brain processes visual information to a complex, real ... scene. The researchers were pleasantly surprised at the power ...
Cached Biology News:Smithsonian scientists discover new marine species in eastern Pacific 2Scientists learn the origin of rogue B cells 2Mimicking how the brain recognizes street scenes 2Mimicking how the brain recognizes street scenes 3Mimicking how the brain recognizes street scenes 4
(Date:4/16/2015)... and OSAKA, Japan , April ... Application (CiRA) of Kyoto University and Takeda Pharmaceutical ... work together to develop clinical applications of induced ... failure, diabetes mellitus, neurological disorders and cancer immunotherapy. ... (T-CiRA) is designed to expedite multiple research projects ...
(Date:4/16/2015)...  Schulman Associates IRB, Inc., the industry-leading central IRB ... lease on Laboratory Drive in the heart of ... location will house review board and service staff, which ... and customer service to clients. CBRE ... the deal, while Capital Associates Management, LLC represented the ...
(Date:4/16/2015)... April 16, 2015  In recognition of World Hemophilia Day, ... advocacy groups to illuminate more than 15 prominent landmarks red ... Boston,s Zakim Bridge and Prudential Tower, ... Mercedes-Benz Superdome and Denver,s ... evening of April 17, and coincide with hemophilia community events ...
(Date:4/16/2015)... A new infographic compiles useful information about ... to learn how Apple’s new framework can change the ... ideal since Apple made Research Kit available ... framework for developing medical research apps that Apple announced ... to collect secure clinical data and communicate via subjects’ ...
Breaking Biology Technology:CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 2CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 3Schulman IRB to Open Office in Research Triangle Park, N.C. 2Biogen Shines A Light On Hemophilia Community By Illuminating U.S. Landmarks Red On World Hemophlia Day 2Biogen Shines A Light On Hemophilia Community By Illuminating U.S. Landmarks Red On World Hemophlia Day 3Biogen Shines A Light On Hemophilia Community By Illuminating U.S. Landmarks Red On World Hemophlia Day 4Infographic Illustrates Potential for Research Kit to Impact Clinical Research 2Infographic Illustrates Potential for Research Kit to Impact Clinical Research 3
... Medical,Inc. (Nasdaq: NXTM ), a leading manufacturer ... to current summary,information derived from a registry of ... at home on a more frequent,or daily, basis ... therapy,received three times a week at a dialysis ...
... -- eFuture Information Technology,Inc. (Nasdaq: EFUT ) ... software and services to China,s retail and consumer ... contract to provide its,mySHOP Retail Business Management System ... Co., Ltd. (,Tiens Group,). eFuture will install,the system ...
... past two decades,stem cell transplantation has evolved from ... viable option for patients with hematologic (blood),malignancies and ... Adult Blood and Marrow Stem Cell Transplantation Program,at ... are,responsible for many of the innovations and techniques ...
Cached Biology Technology:NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 2NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 3NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 4NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 5eFuture Signs Contract to Provide Tiens Group with Retail Business Management System 2eFuture Signs Contract to Provide Tiens Group with Retail Business Management System 3eFuture Signs Contract to Provide Tiens Group with Retail Business Management System 4eFuture Signs Contract to Provide Tiens Group with Retail Business Management System 5Stem Cell Transplantation Research at The Cancer Center at Hackensack University Medical Center Aims to Develop 'Designer' Transplants 2Stem Cell Transplantation Research at The Cancer Center at Hackensack University Medical Center Aims to Develop 'Designer' Transplants 3Stem Cell Transplantation Research at The Cancer Center at Hackensack University Medical Center Aims to Develop 'Designer' Transplants 4
Curcumin is an extract of turmeric root with antioxidant, anti-tumor promoter, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in macrophages....
UGT1A6 (D-20)...
... is the smallest electronic pressure controller available ... Parker configured this unit specifically for the ... Used in carrier gas flow control, microfluidic ... and hydro-dynamic focusing, the OEM-EPC offers external ...
... Series Short Stroke Thrust Slide is designed ... mounting envelopes are limited and substantial side-loading ... internal bumpers provide millions of trouble-free cycles ... of composite bushings or recirculating ball bearings ...
Biology Products: