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New effort to find why replacement hips and knees go bad
Date:2/4/2013

images while the imbedded plastic is in the baths.

They will also devise equipment to mimic the mechanical stresses the push and pull of walking or running and techniques to take images in this process as well.

The images and analysis will show when nanoparticles and plastic fragments are cut free, and under which conditions, and to track where they migrate.

The ultimate goal is to give manufacturers targets they can hone in on to make the implant material more resistant to the environment inside us, so that implants last a lifetime.

Samia will be working with Case Western Reserve's Robert W. Brown, Distinguished University Professor in the department of physics, and Mark A. Griswold, director of MRI Research and professor of radiology at the School of Medicine. Their collaborative research team has been recently awarded an Imaging Guided Biomaterials Development pilot grant by the Institute for Advanced Materials (IAM) at the university.

Beyond artificial knees and hips, Samia said the nanoparticles, methods and technologies developed in this study would also be useful for learning how stents, electrodes, artificial organs and other implants degrade inside the body.

"A lot of other materials are used for implants," she said. "It will be interesting to study them over time."


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Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

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