Navigation Links
New effort to find why replacement hips and knees go bad
Date:2/4/2013

A Case Western Reserve University chemistry professor has begun imbedding magnetic nanoparticles in the toughest of plastics to understand why more than 40,000 Americans must replace their knee and hip replacements annually.

Anna C. Samia, an assistant professor who specializes in metallic nanostructures, has been awarded a five-year $600,000 National Science Foundation-CAREER grant to create new materials and equipment to test ultra-high molecular weight polyethylene used to make artificial joints. She and her team of researchers will also develop magnetic particle imaging techniques to monitor degradation and wear.

Ultra-high molecular weight polyethylene can be tougher to scratch than carbon steel and as slick as Teflon, which seemingly makes the material an ideal substitute for hardworking joints. There is, however, a weakness: chemical oxidation degrades the plastic.

While that's known, "Studies that have been done don't identify the mechanisms in situ," Samia said. "We will mimic how the implants age in the body and test how the microstructure of the polymer affects its wear properties while being simultaneously subjected to chemical stress."

Here's how:

Samia will imbed iron oxide-based magnetic nanoparticles, which are biocompatible, in the polyethylene.

Her preliminary research shows that too many nanoparticles weaken the properties of the implant plastic. So, she is tuning the size, composition, and nanoparticle structure and form to develop strongly magnetic polymer composite materials.

This in turn will enable her team to use fewer particles and still get a magnetic signal strong enough to create images that show what's happening to the plastic. The nanoparticles produce distinctive signals when imbedded and when they are free-floating.

Her team will bathe the polyethylene in biological fluids, hydrogen peroxide and strong acids. They will develop techniques to take
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. DRI to led efforts in clean water, sanitation and hygiene solutions in developing nations
2. First special edition updating progress on efforts to map human proteins
3. Mapping effort charts restoration tack for Great Lakes
4. University of Illinois to improve crop yield through photosynthesis in a new global effort
5. Mercury releases contaminate ocean fish: Dartmouth-led effort publishes major findings
6. UC Davis researchers aid effort to sequence the complex wheat genome
7. Degraded military lands to get ecological boost from CU-led effort
8. Global genome effort seeks genetic roots of disease
9. Greater effort needed to move local, fresh foods beyond privileged consumers
10. Efforts to mitigate climate change must target energy efficiency
11. New turtle tracking technique may aid efforts to save loggerhead
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... affects 1 in 100,000 people characterized by a loss ... remains unknown, a new study by a team of researchers ... Germany and other European institutions confirms for the first time ... 6 July in Nature Genetics , is an important ... a sphincter in the lower esophagus opens, allowing food to ...
(Date:7/28/2014)... by the U.S. Food and Drug Administration (FDA) for ... bacterial pathogens inside human cells, including those that cause ... published in mBio , the online open-access journal ... way of identifying non-antibiotic drugs that could one day ... drugs on the list inhibit the growth of at ...
(Date:7/28/2014)... by the University of Arizona has sequenced the complete ... enhance scientists, and agriculturalists, understanding of the growing patterns ... of new rice varieties that are better able to ... hunger challenges. , The paper, "The genome sequence of ... independent domestication," was published online in Nature Genetics ...
Breaking Biology News(10 mins):Mysterious esophagus disease is autoimmune after all 2New route to identify drugs that can fight bacterial infections 2Generating a genome to feed the world: UA-led team sequences African rice 2Generating a genome to feed the world: UA-led team sequences African rice 3Generating a genome to feed the world: UA-led team sequences African rice 4
... pollution from power plants and automobiles is destroying the ... pollinating insects to follow scent trails to their source, ... partially explain why wild populations of some pollinators, particularly ... declining in several areas of the world, including California ...
... may be so old that dinosaurs once lumbered along its ... of Colorado at Boulder and the California Institute of Technology. ... to show the Grand Canyon may have formed more than ... 40 million to 50 million years. The researchers gathered ...
... Researchers from all over the world have been ... mouth and saliva cells to carry out the DNA analysis., ... (director of the Laboratory of Genetic Identification of the ... by the court in cases of paternity tests, for the ...
Cached Biology News:Flowers' fragrance diminished by air pollution, University of Virginia study indicates 2Grand Canyon may be as old as dinosaurs, says new study 2Grand Canyon may be as old as dinosaurs, says new study 3Fraud attempt in a paternity test modifies action protocol in DNA tests 2
(Date:7/29/2014)... Denver, CO (PRWEB) July 29, 2014 ... and soiled linen collection and transport solutions for hospitals, ... Society for Healthcare Engineering (ASHE) Annual Conference & Technical ... TransVac will present its technology for making hospitals cleaner, ... operational costs over the hospital’s life cycle. Staff ...
(Date:7/29/2014)... , July 29, 2014  Sigma-Aldrich Corporation (NASDAQ: ... energy use, increased its investment in Green Chemistry and ... the world last year, the Company announced Monday in ... Science Changed the World? The report ... honors for being a responsible corporate citizen, including recognition ...
(Date:7/29/2014)... July 29, 2014 G-CON Manufacturing Inc., ... cleanrooms, today announced a new leadership appointment designed to ... States and abroad. , Maik Jornitz, Chief Operating ... company’s President charged with leading the pioneering company through ... enter this stage of development and look forward to ...
(Date:7/29/2014)... Dr. Jason Wendel – recipient of a ... of the Top 10 Plastic Surgeon Specialists for Nashville, TN ... His complete line includes a Hydration Booster, Retexturing Night Crème, ... and skin a younger, more radiant appearance while protecting them ... different, that is why at Dr. J. J. Wendel Plastic ...
Breaking Biology Technology:TransVac Presents Cost Saving Technology at ASHE Conference for Keeping Hospitals Cleaner 2Sigma-Aldrich Achieves Record Success in Environmental, Community Initiatives 2Sigma-Aldrich Achieves Record Success in Environmental, Community Initiatives 3G-CON Manufacturing, Inc. Announces Maik Jornitz as President 2Dr. J. J. Wendel Launches New Line of Skin Care Products 2
... Shows No Thrombosis, Low MACE Rates ... Thirty Patients, ABBOTT PARK, Ill., March 13 ... first clinical trial of a,fully bioabsorbable drug eluting stent ... thrombosis, no clinically driven target,lesion revascularizations (retreatment of a ...
... BERKELEY, Calif., March 13 Nile Therapeutics,Inc. (OTC ... and,full year financial results for 2007. Participants may ... the investor relations section of,Nile,s website at ... company,s website until the next quarterly conference call., ...
... Unigene,Laboratories, Inc. (OTCBB: UGNE) announced that it ... release titled "Stonegate Report About Unigene,Laboratories Inc.", ... Company,s,policies and procedures, Unigene does not endorse, ... by analysts and unrelated third,parties. Any opinions, ...
Cached Biology Technology:The Lancet Publishes Results From World's First Clinical Trial of a Fully Bioabsorbable Drug Eluting Coronary Stent 2The Lancet Publishes Results From World's First Clinical Trial of a Fully Bioabsorbable Drug Eluting Coronary Stent 3The Lancet Publishes Results From World's First Clinical Trial of a Fully Bioabsorbable Drug Eluting Coronary Stent 4Nile Therapeutics Reports 2007 Fourth Quarter and Full Year Financial Results 2Nile Therapeutics Reports 2007 Fourth Quarter and Full Year Financial Results 3Unigene Restates Policy on Analyst Reports 2
A robust formulation of Taq Polymerase supplied with a 10X colored reaction buffer which allows Direct Gel-Loading...
...
Borrelia Burgdorfen (IgG) -Ab EIA Sample Size: 100 l...
... inhibitor that noncovalently binds and inactivates neutral pancreatic ... RNase 1, T1, T2, H, U1, U2 or ... inhibitor in that it has a more robust ... RNase in the absence of DTT or other ...
Biology Products: