Navigation Links
New effort to find why replacement hips and knees go bad
Date:2/4/2013

A Case Western Reserve University chemistry professor has begun imbedding magnetic nanoparticles in the toughest of plastics to understand why more than 40,000 Americans must replace their knee and hip replacements annually.

Anna C. Samia, an assistant professor who specializes in metallic nanostructures, has been awarded a five-year $600,000 National Science Foundation-CAREER grant to create new materials and equipment to test ultra-high molecular weight polyethylene used to make artificial joints. She and her team of researchers will also develop magnetic particle imaging techniques to monitor degradation and wear.

Ultra-high molecular weight polyethylene can be tougher to scratch than carbon steel and as slick as Teflon, which seemingly makes the material an ideal substitute for hardworking joints. There is, however, a weakness: chemical oxidation degrades the plastic.

While that's known, "Studies that have been done don't identify the mechanisms in situ," Samia said. "We will mimic how the implants age in the body and test how the microstructure of the polymer affects its wear properties while being simultaneously subjected to chemical stress."

Here's how:

Samia will imbed iron oxide-based magnetic nanoparticles, which are biocompatible, in the polyethylene.

Her preliminary research shows that too many nanoparticles weaken the properties of the implant plastic. So, she is tuning the size, composition, and nanoparticle structure and form to develop strongly magnetic polymer composite materials.

This in turn will enable her team to use fewer particles and still get a magnetic signal strong enough to create images that show what's happening to the plastic. The nanoparticles produce distinctive signals when imbedded and when they are free-floating.

Her team will bathe the polyethylene in biological fluids, hydrogen peroxide and strong acids. They will develop techniques to take
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. DRI to led efforts in clean water, sanitation and hygiene solutions in developing nations
2. First special edition updating progress on efforts to map human proteins
3. Mapping effort charts restoration tack for Great Lakes
4. University of Illinois to improve crop yield through photosynthesis in a new global effort
5. Mercury releases contaminate ocean fish: Dartmouth-led effort publishes major findings
6. UC Davis researchers aid effort to sequence the complex wheat genome
7. Degraded military lands to get ecological boost from CU-led effort
8. Global genome effort seeks genetic roots of disease
9. Greater effort needed to move local, fresh foods beyond privileged consumers
10. Efforts to mitigate climate change must target energy efficiency
11. New turtle tracking technique may aid efforts to save loggerhead
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... , Jul. 31, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market ... it has filed provisional patent 62/198989 for ... invention highlights a method to advance crypto-currencies such as ... introducing a common, uniform way to manage all payments.  ...
(Date:7/23/2015)... 23, 2015 Aware, Inc. (NASDAQ: AWRE ), ... financial results for its second quarter ended June 30, 2015.  ... was $4.5 million, a decrease of 33% compared to $6.8 ... the second quarter of 2015 was $0.3 million, or $0.01 ... per diluted share, in the same period a year ago.  ...
(Date:7/20/2015)...  Acuity Market Intelligence,s latest research "The Global ... and Privacy" forecasts that between 2014 and 2020 ... downloaded to smart mobile devices by 2.2 billion ... projected to generate more than $67.9 billion in ... period.    "Biometrics is at the ...
Breaking Biology News(10 mins):NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6Biometrics on Smart Mobile Devices to Redefine Digital Identity with 12.9 Billion Biometric App Downloads between 2014 and 2020 2
... The Howard Hughes Medical Research Institute today announced that ... among 50 scientists nationwide to be appointed HHMI Early ... associate member of the Center,s Basic Sciences Division, and ... Center,s Human Biology and Public Health Sciences divisions, each ...
... tiny semipalmated sandpipers embark on their annual odyssey from the ... set out on one of the world,s longest migrations. On ... of Fundy on the Canadian east coast, where they spend ... which have some of the highest levels of n-3 fatty ...
... stocking has on aquatic insects in mountain lakes can ... a study completed by U.S. Forest Service and University ... current online issue of the journal Freshwater Biology where ... management practices now in use in California mountain lakes ...
Cached Biology News:Two Hutchinson Center researchers named HHMI Early Career Scientists 2Quails get super fit by simply eating omega-3 diet 2Study assesses impact of fish stocking on aquatic insects 2
(Date:7/29/2015)... , July 30, 2015 ... la santé, publie ses résultats pour le premier ... commente les résultats. Visionner l,interview ... http://www.eurobusinessmedia.com/ceo-direct/sanofi/sanofi-h1-2015-results-interview-with-ceo-olivier-brandicourt?utm_source=ceo-direct&utm_medium=wire Au sommaire de ... - Moteurs de croissance - ...
(Date:7/29/2015)... MONTREAL , July 29, 2015 /PRNewswire/ - BioAmber Inc. ... Laurin , the Company,s Chief Financial Officer has resigned.  ... former Chief Financial Officer who retired in December 2014, ... search for a permanent successor.     Andy ... Mr. Laurin and ensure a smooth transition.  Andy was ...
(Date:7/29/2015)... 2015 Research and ... of the "Global Biosimilars Market, 2015 - ... The Global Biosimilars Market, 2015 - 2025, report ... biosimilars market. With the blockbuster biologics losing patent ... biosimilars are being viewed as viable substitutes to ...
(Date:7/29/2015)... 29, 2015  Pfenex Inc. (NYSE MKT: PFNX) announced ... be released on Thursday, August 13, 2015, before the ... management will host a conference call to discuss the ... release outlining the financial results and business update will ... Please call 1-866-376-8058 (US) or 1-412-542-4131 (international) and reference ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 2Global Biosimilars Market to 2025: Monoclonal Antibodies (mAbs), Insulin, Interferons, G-CSF/ GM-CSF, Erythropoietins and Others 3Pfenex To Report Second Quarter 2015 Results and Provide Business Update on Thursday, August 13, 2015 2
... States Health Alliance , a regional health care system ... Milwaukee-based Johnson Controls, Inc. , for system-wide installation ... will be installed throughout the health care system, including ... a variety of voice and data services. , ,Mountain ...
... pictured here in 2001 in his Primate Center lab. Source: ... anatomy professor James Thomson attempted to separate hype ... cell research, which in some cases uses tissue from human ... 200 at the UW Memorial Union as part of the ...
... a job offer from one of the employers youve been tangoing ... Think of it as getting an interview but squared. It means ... when we are wanted (not to mention the prospect of getting ... our good judgment. , ,Taking a job is not like going ...
Cached Biology Technology:Tennessee health care system to install Johnson Controls wireless tech 2UW stem cell guru outlines scientific and political future 2UW stem cell guru outlines scientific and political future 3Ten red flags in your Midwest technology offer letter 2Ten red flags in your Midwest technology offer letter 3Ten red flags in your Midwest technology offer letter 4Ten red flags in your Midwest technology offer letter 5
... for isolation and affinity purification of ... peptides. Hydrophobic, monodisperse magnetic particles (2.8 ... groups, further surface activation is not ... with optimal orientation for affinity purification ...
ZO-2 (H-110)...
p-Bcl-2 (Thr 74)...
Derlin-2 (C-18)...
Biology Products: