Navigation Links
New discovery could aid development of elusive bovine mastitis vaccine
Date:6/7/2010

Researchers have discovered components of the bovine mastitis-causing bacterium, Streptococcus uberis that play a key role in the disease. This discovery could lead the way to finally developing a vaccine for this endemic disease, which costs UK farmers alone nearly 200M per year, requires the large scale use of antibiotics, causes pain to cows and dramatically reduces milk yield. A solution to this problem will be an important contribution to the future security of our food supply in the UK. The research is due to be published in Veterinary Research.

BBSRC-funded researcher Professor James Leigh and his team from The University of Nottingham, along with colleagues at the Institute for Animal Health and the University of Oxford, have discovered that Streptococcus uberis a major cause of bovine mastitis uses the enzyme SrtA to anchor at its surface the proteins required for it to cause disease. They have also identified the individual anchored proteins that are required for the bacterium to withstand the responses within the udder that are trying to eliminate it.

Professor Leigh said: "What's really exciting about this is that we've discovered elements of one of the main culprits in bovine mastitis that could actually lead to a vaccine in the future.

"By identifying which components of the bacteria play a role in causing the disease, we can see exactly where to hit it with a vaccine to stop it ever becoming a problem."

At present bovine mastitis requires the large scale use of antibiotics to treat the disease and we know that this may lead to problems of antibiotic resistance down the line. Unfortunately, apart from good husbandry, there is little that can be done to prevent the disease at present.

The team is funded by the Biotechnology and Biological Sciences Research Council (BBSRC) under a scheme that aims to find sustainable ways to reduce the impact of endemic diseases of farm animals on the economy of UK farming industry and the welfare of animals that are kept for meat, eggs and dairy products. This is the BBSRC Combating Endemic Diseases of Farmed Animals for Sustainability (CEDFAS) initiative.

Professor Douglas Kell, BBSRC Chief Executive said: "To feed a growing global population we need to increase food production by 70% by 2050. We have to do this in a sustainable and ethical way and ensure that the UK farming industry remains strong. Endemic diseases of farm animals are extremely costly and cause significant welfare issues. This development is a welcome step towards preventing the suffering and losses associated with bovine mastitis."


'/>"/>

Contact: Nancy Mendoza
press.office@bbsrc.ac.uk
44-179-341-3355
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Related biology news :

1. Discovery may help defang viruses
2. Stomach stem cell discovery could bring cancer insights
3. Symposium marks 30th anniversary of discovery of third domain of life
4. Emory paleontologist reports discovery of carnivorous dinosaur tracks in Australia
5. Natural product discovery by Cleveland medical researchers blocks tissue destruction
6. Researchers discovery may lead to hypertension treatment
7. Yale discovery suggests protein may play a role in severe asthma
8. Galapagos and Cystic Fibrosis Foundation Therapeutics announce drug discovery collaboration
9. Profound immune system discovery opens door to halting destruction of lupus
10. Scripps Research discovery leads to broad potential applications in CovX-Pfizer deal
11. New discovery could reduce the health risk of high-fat foods
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... Lithuania , March 21, 2017   ... and object recognition technologies, today announced the release ... kit (SDK), which provides improved facial recognition using ... cameras on a single computer. The new version ... to improve accuracy, and it utilizes a Graphing ...
(Date:3/20/2017)... At this year,s CeBIT Chancellor Dr. Angela ... The Chancellor came to the DERMALOG stand together with the Japanese Prime ... partner country. At the largest German biometrics company the two government leaders ... iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
(Date:3/13/2017)... Future of security: Biometric Face Matching software  Continue ... ... to match face pictures against each other or against large databases. The recognition ... ... software for biometric Face Matching on the market. The speed is at 100 ...
Breaking Biology News(10 mins):
(Date:5/22/2017)... ... May 22, 2017 , ... Cancer diagnostics ... in booth B2 at the Association for Pathology Informatics Annual Summit ... addition to demonstrating its Cancer Diagnostic Cockpit and Consultation Portal, Inspirata will present ...
(Date:5/19/2017)... PA (PRWEB) , ... May 19, 2017 , ... ... its QED Proof-of-Concept Program. Academic researchers with technologies ripe for commercialization, and ... New Jersey and Delaware, are encouraged to submit proposals. QED, now in its ...
(Date:5/18/2017)... ... May 17, 2017 , ... NDA Partners Chairman Carl Peck, MD , ... Advantar Laboratories and President of Pharmaceutical Development Business Unit of Cardinal Health, has joined ... Cardinal Health, he was former Chief Operating Officer at Anaborex, Senior VP and General ...
(Date:5/18/2017)... (PRWEB) , ... May 17, 2017 , ... ... and equipment for varying industries, including food and dairy, munitions, and pharmaceutical/biotech, recently ... operator safety and ease of use. The improvement in technology comes on the ...
Breaking Biology Technology: