Navigation Links
New device detects heart disease using less than one drop of blood
Date:6/1/2009

Testing people for heart disease might be just a finger prick away thanks to a new credit card-sized device created by a team of researchers from Harvard and Northeastern universities in Boston. In a research report published online in The FASEB Journal (http://www.fasebj.org), they describe how this device can measure and collect a type of cells needed to build vascular tissue, called endothelial progenitor cells, using only 200 microliters of blood. The development is also significant because it allows scientists to collect these cells much more easily than current techniques allow, bringing laboratory-created tissue for vascular bypass surgeries another step closer to reality.

"This simple device is a promising tool for the pediatric and adult population in detecting, diagnosing, monitoring, and providing the option of treating cardiovascular disease by utilizing a small quantity of blood," said lead researcher Shashi K. Murthy of the Department of Chemical Engineering at Northeastern University in Boston.

To collect the cells, the device works similar to Velcro or a magnet. Specifically, the inside is coated with antibodies that only bind to endothelial progenitor cells. Blood flows through the device through a funnel-like opening (except the blood enters through the narrow end and exits through the wide end), passes over the antibodies, and endothelial progenitor cells are "picked up" in the process. In addition to allowing researchers to collect cells from a very small amount of blood, the device's design also provides researchers with a new model to study the effects that blood flow in the body has on cell binding (like clots form in arteries).

"Most immediately, this is could be a new tool to assess cardiovascular health that cuts the amount of blood needed down to a pin prick. Its compact size might make it an excellent tool for use in developing countries where access to medical laboratories does not exist," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "In addition, this moves much closer to a future where new blood vessels, veins and arteries for transplants no longer need to be grafted from patient's bodies. The amount of pain and recovery times for bypass surgeries would be reduced significantly."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. Study shows CGM devices also benefit people with type 1 diabetes
2. MIT’s implantable device offers continuous cancer monitoring
3. Chemical found in medical devices impairs heart function
4. Device protects transplanted pancreatic cells from the immune system
5. NIST-Cornell team builds worlds first nanofluidic device with complex 3-D surfaces
6. BIO-key(R) Granted Patent for Trusted Biometric Device Security Solution
7. Futronic Launches FS22 Fingerprint Access Control Device
8. NC State finds new nanomaterial could be breakthrough for implantable medical devices
9. Linking Proteins, Wires, Dots, and Molecules into Useful Devices
10. Caltech engineers build firast-ever multi-input plug-and-play synthetic RNA device
11. Nanodiamond drug device could transform cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... , March 31, 2016   ... ("LegacyXChange" or the "Company") LegacyXChange is excited ... of its soon to be launched online site for ... https://www.youtube.com/channel/UCyTLBzmZogV1y2D6bDkBX5g ) will also provide potential shareholders a ... DNA technology to an industry that is notorious for ...
(Date:3/29/2016)... 29, 2016 LegacyXChange, Inc. (OTC: ... and SelectaDNA/CSI Protect are pleased to announce our successful ... a variety of writing instruments, ensuring athletes signatures against ... collectibles from athletes on LegacyXChange will be assured of ... DNA. Bill Bollander , CEO states, ...
(Date:3/22/2016)... India , March 22, 2016 /PRNewswire/ ... market research report "Electronic Sensors Market for Consumer ... Proximity, & Others), Application (Communication & IT, ... Geography - Global Forecast to 2022", published ... industry is expected to reach USD 26.76 ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Sequenom, Inc. (NASDAQ: ... enabling healthier lives through the development of innovative products ... the United States denied its ... the claims of Sequenom,s U.S. Patent No. 6,258,540 (",540 ... criteria established by the Supreme Court,s Mayo Collaborative Services ...
(Date:6/27/2016)... ... 27, 2016 , ... Newly created 4Sight Medical Solutions ... the healthcare market. The company's primary focus is on new product introductions, to ... that are necessary to help companies efficiently bring their products to market. , ...
(Date:6/27/2016)... June 27, 2016   Ginkgo Bioworks , a ... engineering, was today awarded as one of the ... the world,s most innovative companies. Ginkgo Bioworks is ... the real world in the nutrition, health and ... directly with customers including Fortune 500 companies to ...
(Date:6/24/2016)... ... 2016 , ... While the majority of commercial spectrophotometers and fluorometers use the ... models are higher end machines that use the more unconventional z-dimension of 20mm. ... the bottom of the cuvette holder. , FireflySci has developed several Agilent flow ...
Breaking Biology Technology: