"The strength of this resistance is because it has come from a different plant family, which the pathogen has not had any chance to adapt to. Through genetic modification, we can now transfer this resistance across plant species boundaries in a way traditional breeding cannot," said Dr Zipfel.
Published in the journal Nature Biotechnology, the finding, that plant recognition receptors can be successfully transferred from one plant family to another provides a new biotechnological solution to engineering disease resistance. The Zipfel group is currently extending this work to other crops including potato, apple, cassava and banana that all suffer from important bacterial diseases, particularly in the developing world.
"A guiding principle in plant pathology is that most plants tend to be resistant to most pathogens. Cyril's work indicates that transfer of genes that contribute to this basic innate immunity from one plant to another can enhance pathogen resistance," commented Professor Sophien Kamoun, Head of the Sainsbury Laboratory. "The implications for engineering crop plants with enhanced resistance to infectious diseases are very promising."
This research was funded by the Gatsby Charitable Foundation and the Two Blades Foundation, who have patented the technology on behalf of the inventors, and involved research groups from INRA/CNRS in France, the University of California, Berkeley and Wageningen University in the Netherlands.
|Contact: Andrew Chapple|
Norwich BioScience Institutes