Navigation Links
New computational technique allows comparison of whole genomes as easily as whole books
Date:1/28/2009

id. The new method did classify several so-far unclassified bacteria, however.

The major differences are found not in how the organisms are grouped, but in the relative position of these groups in the organism trees, he said.

Finally, Kim and his colleagues analyzed the genomes of several hundred viruses, including several that could not be classified.

"Some viruses have no or few highly conserved common genes to other viruses, thus, the gene alignment-based method cannot find relationship among such groups, but we think we can," he said.

Because of the vast amount of whole genome sequence data, all of Kim's analyses monopolized a computer cluster of 320 CPUs (central processing units) for over a year.

Kim stressed the major difference between FFP and gene-centric comparisons of genomes: FFP takes into account all or most of the DNA or protein sequences in the genome, while gene alignment analysis chooses a small set of genes out of large number of genes in each organisms, and uses that to represent the organism.

"The fallacy of the view that organisms can be represented by a small set of their genes is really due to our prejudice that genes are us," Kim said. "We know now, more and more, that this is oversimplification.

"It is likely that some of the observations we come up with will turn out to be wrong, but the method will evolve and get better and better as experts come in and tell us where we have gone wrong. The math is there, now we have to remove the human bias as much as possible."

In addition to applying the method to comparative genomics, Kim expects it will help in grouping and finding relationships among sets of other information, such as electronic information encoding text, sounds and images. It may also help in tracing human ancestry and disease demography using whole genome sequences, and in grouping of metagenomic data - the sequences of genome fragments from many organisms, mo
'/>"/>

Contact: Robert Sanders
rsanders@berkeley.edu
510-643-6998
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3 4 5 6

Related biology news :

1. Supercomputer provides massive computational boost to biomedical research at TGen
2. Penn presents inaugural symposium on applied mathematics and computational science
3. Computational biochemist uncovers a molecular clue to evolution
4. Computational mathematical sciences receives NSF grant for undergraduate research
5. Computational actinide chemistry: Are we there yet?
6. Novel technique changes lymph node biopsy, reduces radiation exposure
7. Novel technique changes lymph node biopsy, reduces radiaiton exposure
8. New technique is quantum leap forward in understanding proteins
9. New edition of laboratory manual includes cutting-edge techniques to study gene regulation
10. Novel technique for fluorescence tomography of tumors in living animals
11. These shells dont clam up: Innovative technique to record human impact on coastal waters
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New computational technique allows comparison of whole genomes as easily as whole books
(Date:8/26/2015)... -- The report "Multi-Factor Authentication (MFA) Market by ... & Immigration, Government, Banking, Defense, Commercial Security, Consumer Electronics, ... by MarketsandMarkets, Multi-Factor Authentication Market is expected to reach ... of 17.7% between 2015 and 2020. ... through 169 P ages and in-depth ...
(Date:8/25/2015)... and BELLEVUE, Wash. , Aug. ... advanced robotic systems, announced today it will unveil its ... vehicle (UGV), at the National Tactical Officers Association Conference ... The Guardian S is the first-ever commercially available ... years of research and in-field trials and is protected ...
(Date:8/24/2015)... , August 24, 2015 The ... ,s largest biometrics manufacturer DERMALOG and its customized solutions ... "2015 African Biometrics Company of the Year Award". DERMALOG is ... Nigeria .   -Cross reference: Picture is ... - On Thursday evening, in ...
Breaking Biology News(10 mins):Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 2Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 3Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 4Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 5Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 2Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 3
... generation of cancer chemotherapeutic drugs specifically targets mutant enzymes ... uncontrolled cell growth. As promising as these drugs are, ... the tendency to fight back. A major goal of ... desperation. , In a forthcoming issue of Cancer Cell, ...
... Scientists have identified the first biochemical marker linked to sleep ... in activity when sleep deprivation is prolonged. , Researchers hope ... that will aid diagnosis and treatment of sleep disorders and ... at the wheel of a car or in other dangerous ...
... of these epidermal neural crest stem cells in the ... showing that these cells are distinctly different from other ... valuable resource for future mouse neural crest stem cell ... Maya Sieber-Blum's laboratory, co-authored by Yao Fei Hu, Ph.D., ...
Cached Biology News:Distinguishing friend from foe in the battle against cancer 2Distinguishing friend from foe in the battle against cancer 3First biomarker for human sleepiness identified in fruit flies 2First biomarker for human sleepiness identified in fruit flies 3Stem cells found in adult hair follicles may provide alternative to embryonic stem cells 2
(Date:8/28/2015)... ... August 28, 2015 , ... ... surgeon, Wade McKenna, DO, announced today that the use of sterile, dehydrated amniotic ... complete healing of an otherwise non-healing surgical knee wound. , The case involved ...
(Date:8/28/2015)... NY (PRWEB) , ... August 28, 2015 , ... Since the initial launch of FireflySci ... their quirky humor and excellent customer service. Images such as the Fonz in a ... to add some flavor to the humdrum spectroscopy field. , FireflySci is proud ...
(Date:8/27/2015)... (PRWEB) , ... August 27, 2015 , ... ... opportunity for venture capital funds, investment firms and animal health companies to hear ... have raised $160 million. Several have also received licensing agreements or distribution contracts. ...
(Date:8/27/2015)... ... August 27, 2015 , ... Capital Edge Consulting , a nationwide ... pleased to announce their ranking as one of the top 5000 companies listed on ... companies across the nation. , “It is truly an honor to be recognized as ...
Breaking Biology Technology:Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 2VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 3Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 3
... Growing Generations, the nation,s,largest surrogacy agency, has launched ... to men with HIV and allows them to use,their ... program is made possible due to advances in technology ... the implementation of recent California,legislation enacted in January that ...
... 3 DermTech, a biotechnology,company developing molecular diagnostics ... today announced that Herbert A. Fritsche,Ph.D., has joined ... Chief of Clinical Chemistry at M.D. Anderson Cancer ... development and validation of cancer,diagnostics for early disease ...
... CORAL GABLES, Fla., June 3 Catalyst,Pharmaceutical ... biopharmaceutical company,that acquires, in-licenses, develops and commercializes ... and obsessive compulsive disorders,today announced the filing ... and Exchange Commission (SEC). After the shelf ...
Cached Biology Technology:Growing Generations Announces Surrogacy Program for Men with HIV 2DermTech Names Herbert A. Fritsche, Ph.D., Chief of Clinical Chemistry at M.D. Anderson Cancer Center to Company's Scientific Advisory Board 2Catalyst Pharmaceutical Partners, Inc. Files Form S-3 Shelf Registration Statement 2Catalyst Pharmaceutical Partners, Inc. Files Form S-3 Shelf Registration Statement 3
Agarose, pulse field, 250 g. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1800 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Homo sapiens palladin...
Recombinant Rat Leptin, Ultra Pure...
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Biology Products: