Navigation Links
New compounds discovered that are hundreds of times more mutagenic
Date:1/6/2014

CORVALLIS, Ore. Researchers at Oregon State University have discovered novel compounds produced by certain types of chemical reactions such as those found in vehicle exhaust or grilling meat - that are hundreds of times more mutagenic than their parent compounds which are known carcinogens.

These compounds were not previously known to exist, and raise additional concerns about the health impacts of heavily-polluted urban air or dietary exposure. It's not yet been determined in what level the compounds might be present, and no health standards now exist for them.

The findings were published in December in Environmental Science and Technology, a professional journal.

The compounds were identified in laboratory experiments that mimic the type of conditions which might be found from the combustion and exhaust in cars and trucks, or the grilling of meat over a flame.

"Some of the compounds that we've discovered are far more mutagenic than we previously understood, and may exist in the environment as a result of heavy air pollution from vehicles or some types of food preparation," said Staci Simonich, a professor of chemistry and toxicology in the OSU College of Agricultural Sciences.

"We don't know at this point what levels may be present, and will explore that in continued research," she said.

The parent compounds involved in this research are polycyclic aromatic hydrocarbons, or PAHs, formed naturally as the result of almost any type of combustion, from a wood stove to an automobile engine, cigarette or a coal-fired power plant. Many PAHs, such as benzopyrene, are known to be carcinogenic, believed to be more of a health concern that has been appreciated in the past, and are the subject of extensive research at OSU and elsewhere around the world.

The PAHs can become even more of a problem when they chemically interact with nitrogen to become "nitrated," or NPAHs, scientists say. The newly-disc
'/>"/>

Contact: Staci Simonich
staci.simonich@oregonstate.edu
541-737-0787
Oregon State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Finnish researchers develop quick test kit for detecting phenolic compounds in drinking water
2. Scientists identify promising antiviral compounds
3. NIH to fund collaborations with industry to identify new uses for existing compounds
4. University of Wisconsin chemists find new compounds to curb staph infection
5. Scientists map all possible drug-like chemical compounds
6. Beers bitter compounds could help brew new medicines
7. Scientists identify insect-repelling compounds in Jatropha
8. Screening technique uncovers 5 new plant activator compounds
9. MMV develops framework to assess risk of resistance for antimalarial compounds
10. Compounds shown to thwart stubborn pathogens social propensity
11. University of Albertas designer compounds inhibit prion infection
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New compounds discovered that are hundreds of times more mutagenic
(Date:7/14/2014)... 2014 How does oxygen control insect body size? What ... in the first issue of Current Opinion in Insect ... and more questions. , Current Opinion in Insect Science ... series. It is a review journal that aims to provide ... expanding volume of information published in the field of insect ...
(Date:7/14/2014)... The Biogerontology Research Foundation (BGRF), a UK-based charity ... challenges of a rapidly ageing population, hosted the ... 30th, with Aging Analytics, a company supporting financial ... , The speakers at the forum included: , ... Kong on ,Impact Investment to Advance Longevity Research, ...
(Date:7/14/2014)... discovery and description of Rhipidocyrtus muiri - a ... to represent a new genus and species. The long and ... is discussed in a recent paper published in the open ... male, and only known specimen of Rhipidocyrtus muiri , ... this it was transferred among several researchers in the early ...
Breaking Biology News(10 mins):BGRF hosts inaugural 21st Century Medicine Forum 2Serendipity at the Smithsonian: The 107-year journey of the beetle Rhipidocyrtus muiri 2Serendipity at the Smithsonian: The 107-year journey of the beetle Rhipidocyrtus muiri 3
... the National Institutes of Health will explore the role ... by NIH,s National Institute of Environmental Health Sciences (NIEHS), ... people more vulnerable to heat exposure; changing weather patterns; ... toxic chemicals; and the negative effects of climate change ...
... discovered in the 16-23 million years old sediments of the ... Helophorus sibiricus , a member of the water scavenger ... in Eurasia and reaches even North America. The species was ... based on specimens collected at Lake Baikal. It is aquatic ...
... 2011. In the central Arctic the proportion of old, thick ... largely consists of thin, one-year-old floes. This is one of ... Polar and Marine Research in the Helmholtz Association brought back ... The ship arrived at its home port of Bremerhaven ...
Cached Biology News:NIH launches research program to explore health effects from climate change 2NIH launches research program to explore health effects from climate change 3A living species of aquatic beetle found in 20-million-year-old sediments 2Young and thin instead of old and bulky 2Young and thin instead of old and bulky 3Young and thin instead of old and bulky 4
(Date:7/14/2014)... , July 14, 2014 Cloud Pharmaceuticals, ... design and development, announced today the expansion of ... has been granted supercomputing time at Argonne National ... Through a discretionary allocation of ... Facility (ALCF), researchers at Cloud Pharmaceuticals will use ...
(Date:7/14/2014)... 2014 Throughout this past June ... clinical trials space, representing 38 countries globally, registered ... “Optimizing Patient Participation in Clinical Trials. Attract. Engage. ... internationally renowned R&D expert, Ken Getz, of Tufts ... Drug Development through Patient Centricity. , Throughout this ...
(Date:7/14/2014)... , July 14, 2014 Minerva Neurosciences (NASDAQ: ... of new therapies to treat neuropsychiatric diseases and disorders, ... been appointed vice president of finance and chief accounting ... is a senior executive with more than 20 years ... and life science companies. His background includes the management ...
(Date:7/14/2014)... 14, 2014 PatientCrossroads, pioneer ... announced that three PatientCrossroads-based patient registries—DuchenneConnect, for ... Syndrome International Registry; and the NephCure Kidney ... contracts by the Patient-Centered Outcomes Research Institute ... a new health data network called PCORnet: ...
Breaking Biology Technology:Cloud Pharmaceuticals Granted 1M Hours of Supercomputer Time to Target Orphan Diseases Including Malaria 2Optimizing Patient Participation in Clinical Trials: Attract. Engage. Retain. – eCongress eBox Archives Now Available 2Optimizing Patient Participation in Clinical Trials: Attract. Engage. Retain. – eCongress eBox Archives Now Available 3Optimizing Patient Participation in Clinical Trials: Attract. Engage. Retain. – eCongress eBox Archives Now Available 4Optimizing Patient Participation in Clinical Trials: Attract. Engage. Retain. – eCongress eBox Archives Now Available 5Minerva Neurosciences Announces Appointment Of Frederick W. Ahlholm As VP Of Finance And Chief Accounting Officer 2PatientCrossroads Fuels Development of New National Clinical Research Network 2PatientCrossroads Fuels Development of New National Clinical Research Network 3
... , Most Basic Recommended Cecil Instrumentation: , ... 500 l loop , Fraction collector , Column ... : , Researchers need to understand ... protein expression in healthy and diseased cells. , Hence the ...
... reliable and accurate long-range PCR and RT-PCR , ... RT-PCR Kits provide dedicated and highly reliable solutions for long-range,amplification from genomic DNA and cDNA. ... , QIAGEN LongRange PCR ... Amplification of extremely long PCR products up to 40 kb DNA or,12.5 kb ...
... LOS ANGELES, CA (August 10, 2006) - DoveBid, Inc., ( http://www.dovebid.com ... auction and valuation services, announced , today it ... Exchange auction online, on August 15, 2006. The event marks a milestone ... practice, and is expected , to bring to-date ...
Cached Biology Technology:Semi Preparative Purification of Proteins 2QIAGEN LongRange PCR and 2Step RT-PCR Kits 2World Class Life Science and Pharmaceutical Companies Leverage DoveBid s Global Reach for Asset Management and Disposition 2World Class Life Science and Pharmaceutical Companies Leverage DoveBid s Global Reach for Asset Management and Disposition 3
Immunogen: C terminus [VQLKRSKNDSKPYC] of cardiac elav-type RNA-binding protein (ETR-3) Storage: -20 C, Avoid Freeze/Thaw Cycles...
Standard 2" and 3" Fiberboard Boxes can be sold separately or with 16, 25, 36, 49, 64, 81 or 100 cell dividers. Fiberboard boxes can also be ordered with corresponding freezer racks...
...
Luminometers...
Biology Products: