Navigation Links
New compounds discovered that are hundreds of times more mutagenic
Date:1/6/2014

CORVALLIS, Ore. Researchers at Oregon State University have discovered novel compounds produced by certain types of chemical reactions such as those found in vehicle exhaust or grilling meat - that are hundreds of times more mutagenic than their parent compounds which are known carcinogens.

These compounds were not previously known to exist, and raise additional concerns about the health impacts of heavily-polluted urban air or dietary exposure. It's not yet been determined in what level the compounds might be present, and no health standards now exist for them.

The findings were published in December in Environmental Science and Technology, a professional journal.

The compounds were identified in laboratory experiments that mimic the type of conditions which might be found from the combustion and exhaust in cars and trucks, or the grilling of meat over a flame.

"Some of the compounds that we've discovered are far more mutagenic than we previously understood, and may exist in the environment as a result of heavy air pollution from vehicles or some types of food preparation," said Staci Simonich, a professor of chemistry and toxicology in the OSU College of Agricultural Sciences.

"We don't know at this point what levels may be present, and will explore that in continued research," she said.

The parent compounds involved in this research are polycyclic aromatic hydrocarbons, or PAHs, formed naturally as the result of almost any type of combustion, from a wood stove to an automobile engine, cigarette or a coal-fired power plant. Many PAHs, such as benzopyrene, are known to be carcinogenic, believed to be more of a health concern that has been appreciated in the past, and are the subject of extensive research at OSU and elsewhere around the world.

The PAHs can become even more of a problem when they chemically interact with nitrogen to become "nitrated," or NPAHs, scientists say. The newly-disc
'/>"/>

Contact: Staci Simonich
staci.simonich@oregonstate.edu
541-737-0787
Oregon State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Finnish researchers develop quick test kit for detecting phenolic compounds in drinking water
2. Scientists identify promising antiviral compounds
3. NIH to fund collaborations with industry to identify new uses for existing compounds
4. University of Wisconsin chemists find new compounds to curb staph infection
5. Scientists map all possible drug-like chemical compounds
6. Beers bitter compounds could help brew new medicines
7. Scientists identify insect-repelling compounds in Jatropha
8. Screening technique uncovers 5 new plant activator compounds
9. MMV develops framework to assess risk of resistance for antimalarial compounds
10. Compounds shown to thwart stubborn pathogens social propensity
11. University of Albertas designer compounds inhibit prion infection
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New compounds discovered that are hundreds of times more mutagenic
(Date:4/2/2015)... , April 2, 2015 At its 2015 ... Lake City , the American College of Medical ... new directors to its Board.  Members of the ACMG ... and for forming and advancing its policies and programs. ... profession. "It,s an eventful time in medical ...
(Date:4/1/2015)... OXFORD, Conn. , Apr. 1, 2015  NXT-ID, ... a biometric authentication company focused on the growing mobile ... number of Wocket smart wallets is underway to early ... early access group includes usage at retail outlets including ... CVS Pharmacy. Users report Wocket was accepted at all ...
(Date:3/31/2015)... --  Guidepoint , a leading global research services firm, ... TRACKER, part of the Guidepoint TRACKER suite ... device and therapeutics markets. The Post-Surgical Pain Management TRACKER ... share, and adoption rates across three major modalities used ... The Post-Surgical Pain Management TRACKER will provide length ...
Breaking Biology News(10 mins):American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3
... Although the two disorders may seem dissimilar, epilepsy and ... to have schizophrenia, and a family history of epilepsy ... known whether the converse is true, i.e., whether a ... epilepsy. Multiple studies using varied investigative techniques ...
... Cracking the Neural Code: Third Annual Aspen Brain Forum ... of Sciences and The Aspen Brain Forum Foundation WHEN: ... www.nyas.org/NeuralCode One of the greatest challenges in neuroscience ... neuronal circuits gives rise to higher order cognition and behavior. ...
... - New research suggests that there could be health ... This antioxidant is a naturally occurring pigment that gives ... certain greens. It also converts to vitamin A, and ... essential nutrient. But scientists at Ohio State University ...
Cached Biology News:Evidence of familial vulnerability for epilepsy and psychosis 2Researchers find potential 'dark side' to diets high in beta-carotene 2Researchers find potential 'dark side' to diets high in beta-carotene 3Researchers find potential 'dark side' to diets high in beta-carotene 4
(Date:5/1/2015)... 1, 2015 A new report ... drugs will reach $22.4bn in 2019. That revenue forecast ... and Market Prospects 2015-2025 ,  published in ... is to provide forecasts and qualitative analyses of the ... and consultancy in London, UK . ...
(Date:4/30/2015)... Spirax Sarco, the leader in product ... announce that for the first time in the company’s ... a Queen’s Award for Innovation – the UK’s highest ... of a unique flowmeter. , The Spirax Sarco ... steam flow measurement. The device provides reliable, accurate ...
(Date:4/30/2015)... 30, 2015 Nitto Avecia, a ... its increased capacity and production capability to serve ... variety and service fulfillment continues to drive Nitto ... process throughput capacities. , In Fall ... downstream process equipment at its Milford, MA facility, ...
(Date:4/30/2015)... SAN DIEGO , April 30, 2015 /PRNewswire/ ... company engaged in the development of biosimilar therapeutics ... today announced the closing of its previously announced ... common stock at a public offering price of ... full by the underwriters of their option to ...
Breaking Biology Technology:Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 2Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 3Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 4Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 5Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3Biotechnology Manufacturer Nitto Avecia Expands Capacity to Meet Client Demand 2Pfenex Inc. Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 2
... March 17 VION,PHARMACEUTICALS, INC. (Nasdaq: VIOND ) ... of 2007., The Company reported a net loss ... ended December 31, 2007, compared with a net loss ... common shares,outstanding for the years ended December 31, 2007 ...
... panel for assessment of current risk ... ... Limited (TSX: GEN),a company focused on developing molecular diagnostic tests ... diseases and personalized,health management, today announced that its abstract describing ...
... Axial Biotech, Inc., a company,revolutionizing spine care ... technologies, announced today that it has met several,major ... genetic,prognostic test for Adolescent Idiopathic Scoliosis (AIS) and ... B financing. The Series B financing was,led by ...
Cached Biology Technology:Vion Reports 2007 Fourth Quarter and Year-End Results 2Vion Reports 2007 Fourth Quarter and Year-End Results 3Vion Reports 2007 Fourth Quarter and Year-End Results 4GeneNews selected to present late-breaking abstract at AACR Annual Meeting 2Axial Biotech Meets Major Scientific Milestones; Receives $6 Million Tranche of Series B Financing 2
Request Info...
Immunogen: VDAC3 Protein Storage: -20 C, Avoid Freeze/Thaw Cycles...
... 75 x 25 mm; ... recommended for immunohistochemistry of paraffin-embedded sections, ... end, markings will not ... precleaned, ...
Complete cell culture media with cytokines...
Biology Products: