Navigation Links
New composite material may restore damaged soft tissue
Date:8/1/2011

long-term stability, the researchers injected different concentrations of PEG and HA under the skin and into the back muscle of rats, shone a green LED light on them to "gel" the material, and used magnetic resonance imaging (MRI) to monitor the persistence of the implant over time. The implants were examined at 47 and 110 days with MRIs and removed. Direct measurements and MRIs of the implants showed that the ones created from HA and the highest tested concentration of PEG with HA stayed put and were the same size over time compared to injections of only HA, which shrank over time.

The researchers evaluated the safety and persistence of the PEG-HA implants with a 12-week experiment in three volunteers already undergoing abdominoplasty, or "tummy tucks." Technicians injected about five drops of PEG-HA or HA alone under the belly skin. None of the participants experienced hospitalization, disability or death directly related to the implant, which was about 8 mm longor about as wide as a pinky fingernail. However, the participants said they sensed heat and pain during the gel setting process. Twelve-weeks after implantation, MRI revealed no loss of implant size in patients. Removal of the implants and inspection of the surrounding tissue revealed mild to moderate inflammation due to the presence of certain types of white blood cells. The researchers said the same inflammatory response was seen in rats, although the types of white blood cells responding to implant differed between the rodents and humans, a difference the researchers attribute to the back muscles the target tissue in the ratsbeing different than human belly fat.

"We still have to evaluate the persistence and safety of our material in other types of human tissues, like muscle or less fatty regions under the skin of the face, so we can optimize it for specific procedures," says Elisseeff.

Elisseeff said the team has especially high hopes for the composite's use in people w
'/>"/>

Contact: Vanessa McMains
vmcmain1@jhmi.edu
410-502-9410
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New ORNL carbon composite holds promise for bionics
2. Rice University lab creates self-strengthening nanocomposite
3. So-called sandfish could help materials handling and process technology specialists
4. Extreme nature helps scientists design nano materials
5. Yale journal finds nanomaterials may have large environmental footprint
6. NC State finds new nanomaterial could be breakthrough for implantable medical devices
7. TECNALIA investigates advanced biomaterials to make more reliable and hardwearing medical implants
8. Pitt researchers create non-toxic clean-up method for potentially toxic nano materials
9. New smart materials for the brain
10. New reference material can improve testing of multivitamin tablets
11. Crab claws pack strengthening bromide-rich biomaterial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... elements are a key component of phloem, the conductive ... range of signalling molecules. Elongated cylindrical cells are capped ... end-to-end to form sieve tubes which in turn form ... "Sieve elements are very special cells which play an ... little has been known about their differentiation," says Professor ...
(Date:8/1/2014)... Fla. , Aug. 1, 2014  LiveScan Service Provider Binary Biometrics ... owner/operator team. As a result, Binary Biometrics will improve its mobile service capabilities ... Volusia County and service several new cities such as, ... , DeLand , Deltona , ... Helen , New Smyrna Beach , Oak ...
(Date:7/31/2014)... supported by the National Science Foundation (NSF), counters ... accelerates atmospheric warming, indicating instead that certain Arctic ... into the atmosphere. , The study, published ... focuses on thermokarst lakes, which occur as permafrost ... melted fresh water, converting what was previously frozen ...
Breaking Biology News(10 mins):Developmental regulation of important plant phloem components discovered 2Binary Biometrics, Founded by James Timothy White, Expands Services to 13+ Locations With the Addition of Owner/Operator Kevin Morris 2Binary Biometrics, Founded by James Timothy White, Expands Services to 13+ Locations With the Addition of Owner/Operator Kevin Morris 3Certain Arctic lakes store more greenhouse gases than they release 2
... On the first anniversary of the American Recovery and ... nation,s research universities today provided nearly 100 examples of ... paying outsize short- and long-term dividends for the nation. ... $21.5 billion is allocated for research and science infrastructure. ...
... Medical Inc. has obtained a non-exclusive license to ... property developed at Case Western Reserve University,s Department ... (FES) Center in Cleveland. ... manufacturer based in Indiana, Pa., rights to intramuscular ...
... multitude of questions, but sometimes traditional techniques are superior. ... cost, when they relied upon statistical data to monitor ... an indigenous group of people living in the James ... Montreal), have lived in harmony with their environment. They ...
Cached Biology News:Universities highlight benefits of stimulus research funding 2Universities highlight benefits of stimulus research funding 3Listen to the natives for better moose monitoring 2
(Date:8/1/2014)... 2014 AACC, a global scientific and medical ... unveiled an updated brand identity today that reflects the ... changing healthcare environment and continue to do what they ... get the care they need. " ... an essential role in saving lives and making people ...
(Date:8/1/2014)... , August 1, 2014 According ... Research "Biophotonics Market - Global Industry Analysis, Size, Share, ... was valued at USD 25.16 billion in 2013, which ... growing at a CAGR of 10.4% from 2014 to ... at  http://www.transparencymarketresearch.com/biophotonics-market.html Increasing demand for accurate ...
(Date:8/1/2014)... Mass. (PRWEB) August 01, 2014 BCC ... RNAi DRUG DELIVERY: TECHNOLOGIES AND GLOBAL MARKETS , ... technologies is expected to grow to nearly $38.8 billion ... (CAGR) of 27.2%. The aptamer delivery category, the fastest ... phenomenal 58.2% CAGR. , The field of RNAi therapeutics ...
(Date:8/1/2014)... Testing the mechanical properties of microtissues ... embryonic development. How and why embryonic stem ... distinct tissues is important because abnormalities can lead ... Melissa Kinney, and Rabbia Saeed worked from the ... to control many aspects of embryo development. ...
Breaking Biology Technology:AACC Debuts Refreshed Brand Identity 2Global Biophotonics Market is Expected to Reach USD 50.20 Billion in 2020: Transparency Market Research 2Global Biophotonics Market is Expected to Reach USD 50.20 Billion in 2020: Transparency Market Research 3Global Biophotonics Market is Expected to Reach USD 50.20 Billion in 2020: Transparency Market Research 4Global Market for RNAi Drug Delivery Technologies to Reach $38.8 Billion in 2018; Aptamer Delivery Segment Surging at 58.2% CAGR 2Global Market for RNAi Drug Delivery Technologies to Reach $38.8 Billion in 2018; Aptamer Delivery Segment Surging at 58.2% CAGR 3Study Links Biomechanics and Gene Expression in Stem Cells 2
... N.C., June 9, 2011 The David H. Murdock ... Immune Tolerance Institute, Inc. (ITI) as a next step ... the North Carolina Research Campus in Kannapolis, NC. Driven ... of breakthrough treatments for the range of immune-related diseases, ...
... all advanced a few steps closer to their future ... the week of May 9-13, 2011. That,s when ... three of the four robotics competitions at the IEEE ... China. The trio of contests are designed to prove ...
... 2011 Ronald W. Davis, PhD, a pioneer in innovative ... and genomic methods to biological organisms, will receive the 2011 ... Davis, 69, has spent most of his professional ... biochemistry and genetics. He also serves as director of the ...
Cached Biology Technology:David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune Monitoring Laboratory for Biomarker Discovery and Development 2David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune Monitoring Laboratory for Biomarker Discovery and Development 3NIST contests in China put next-gen robot technologies to the test 2NIST contests in China put next-gen robot technologies to the test 3Biochemist and Geneticist Ronald W. Davis Receives $500,000 Gruber Genetics Prize for Pioneering Work in the Development of Biotechnologies that Have Significantly Advanced the Fields of Molecular Genetics and Genomics 2Biochemist and Geneticist Ronald W. Davis Receives $500,000 Gruber Genetics Prize for Pioneering Work in the Development of Biotechnologies that Have Significantly Advanced the Fields of Molecular Genetics and Genomics 3
... long electrophoresis hood is a ... systems. Placed on the transilluminator, ... place and provides a darkroom ... the lab bench. This 15.2 ...
... derived from frozen embedded tissue blocks, which ... to ensure the highest quality. Tissues of ... block, sectioned at a thickness of 7 ... are large (3-5 mm in diameter) in ...
... are derived from frozen embedded tissue blocks, ... procedures to ensure the highest quality. Tissues ... one block, sectioned at a thickness of ... are large (3-5mm in diameter) in comparison ...
... microarrays are derived from Paraffin embedded tissue ... control procedures to ensure the highest quality. ... in one block, sectioned at a thickness ... slides. Sections are large (3-5mm in diameter) ...
Biology Products: