Navigation Links
New clinical trial results show how personalized medicine will alter treatment of genetic disorders
Date:12/26/2007

reactivate dystrophin protein production in small areas of muscle tissue at the injection site of muscular dystrophy patients.

"Dozens of specific sequences will be required for effectively treating the majority of patients with Duchenne muscular dystrophy," writes Dr. Hoffman. "But in order to realize the promise of personalized molecular medicine in muscular dystrophies and, ultimately, other disorders, it will be important to re-evaluate current measures of toxicity, efficacy, and marketing that ensure both safety for the patient, as well as rapid development and distribution of life-saving drugs."

Dr. Hoffman envisions that some parts of the approval process may be developed for DNA-like molecular medicine as a 'class' of drugs, rather than individual testing of hundreds of different sequences.

"The patients and their families are crossing their fingers that the drugs overall chemistry can be shown to be safe," he says.


'/>"/>

Contact: Jennifer Leischer
jleische@cnmc.org
202-476-4500
Children's National Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
2. Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients
3. Phase 2 of Singapores Biomedical Sciences Initiative gains momentum for clinical research
4. Cleveland Clinic leading clinical program to improve early-stage lung cancer detection
5. Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design
6. Study of African traditional medicine will begin world-first clinical trial
7. New clinical data shows chromium picolinate improves cognitive function
8. Vitamin E trials fatally flawed
9. Research team says extraterrestrial impact to blame for Ice Age extinctions
10. Trial seeks genetic fingerprint for predicting drug effectiveness
11. The industrial space age
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... , Dec. 15, 2014 Research and Markets ... addition of the "Samsung Galaxy S5 - ... report to their offering. ... totally different sensing technology than the iPhone 5S, ... sensor in its product. The Galaxy ...
(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM ... Clinical Practices (GCP) audit to confirm its adherence ... regulations. This accomplishment enables HITLAB to conduct regulated ... the highest principles for patient safety and research ... global healthcare access, quality, and delivery with innovative ...
(Date:12/17/2014)... Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ... "Global Chemical Sensor Market 2015-2019" report to ... One major trend upcoming in ... sensors in biomedical applications. Chemical sensors help in ... diagnosis during surgical procedures. The Global Chemical Sensor ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... have cloned a gene that controls the shape of tomatoes, ... huge morphological differences among edible fruits and vegetables, as well ... The gene, dubbed SUN, is only the second ever found ... various tomato varieties, said Esther van der Knaap, lead researcher ...
... at the request of the PIO. , Without a ripple ... though they lack flippers or fins. University of Utah biologists ... and rib muscles to shift their lungs like internal floatation ... when they surface and sideways when they roll. It ...
... the principle of "strength in numbers" more apparent than ... these one-cell organisms -- which number about 5 million ... on Earth -- affect virtually every ecological process, from ... oxygen. But even though microbes essentially rule the ...
Cached Biology News:Crop scientists discover gene that controls fruit shape 2Crop scientists discover gene that controls fruit shape 3Crop scientists discover gene that controls fruit shape 4How alligators rock and roll 2How alligators rock and roll 3How alligators rock and roll 4How alligators rock and roll 5New window opens on the secret life of microbes 2
(Date:12/19/2014)... (PRWEB) December 18, 2014 iLab Solutions, ... the appointment of Siri Bryant as the new Director ... Director of Core Implementations. These two new leadership positions ... customer service by ensuring that iLab continues to meet ... the last four years, iLab has been deployed at ...
(Date:12/19/2014)... 2014 Egenix, Inc. is pleased to announce that ... the Board, to succeed Donald Fresne ; Mr. Fresne ... as a member of the Board.  In recognition of the ... company over almost twenty years, the Board designated Mr. Fresne ... has established a Search Committee to find a suitable replacement ...
(Date:12/17/2014)... “Never say, ‘I cannot do ... Department of Physics, advises young women pursuing careers ... SPIE Women in Optics 18-month planner ... ask questions.” , In the annual planner, women ... ranging from university professor and laboratory researcher to ...
(Date:12/17/2014)... December 17, 2014 Xeno Diagnostics ... following its most recent COLA inspection. Xeno has ... a national healthcare accreditation organization. Accreditation is earned ... quality in day-to-day operations, demonstrate continued accuracy in ... rigorous on-site laboratory survey. , While ...
Breaking Biology Technology:iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3Xeno Diagnostics Receives 3rd Award for Laboratory Excellence 2
... ... ... (Nasdaq: PRXL ), a leading global biopharmaceutical services,organization, today ... Clinical Research Co., Ltd. ("APEX").,The acquisition strengthens PAREXEL,s global capabilities, ...
... SEATTLE, Sept. 26 Today at the ... introduction of a,ground-breaking vaccine to eliminate epidemic ... conjugate vaccine, developed by the Meningitis,Vaccine Project, ... and,PATH and produced by Serum Institute of ...
... CLINTON, N.J., Sept. 26 Mark Roth, Ph.D., ... received a MacArthur,Fellowship award, which includes a grant ... Roth, a member of the Fred Hutchinson ... of "no-strings-attached" support,from the John D. and Catherine ...
Cached Biology Technology:PAREXEL International Completes Acquisition of APEX International Clinical Research Co., Ltd. 2PAREXEL International Completes Acquisition of APEX International Clinical Research Co., Ltd. 3PAREXEL International Completes Acquisition of APEX International Clinical Research Co., Ltd. 4PAREXEL International Completes Acquisition of APEX International Clinical Research Co., Ltd. 5PATH, World Health Organization, and Partners Introduce Meningitis Vaccine in Burkina Faso 2PATH, World Health Organization, and Partners Introduce Meningitis Vaccine in Burkina Faso 3Ikaria Founding Scientist Named 2007 MacArthur Fellow 2
pETDuet-1 is designed for the coexpression of two target genes....
Mouse Laminin-1 MAb (Clone AL-3)...
IEX-1 S/L (H-20)...
... reactivity with rat (100%), mouse ... pig (48%). Slight reactivity ... confirmed by Western blot versus ... Gia-1, Gia-2, rat Gia-3, bovine ...
Biology Products: