Navigation Links
New clinical trial explores novel noninvasive colon cancer screening test
Date:4/2/2012

olonoscopy or do not have access to the procedure. It also can be beneficial for patients during the years in between colonoscopies."

Dr. Markowitz, who is an alumnus investigator of the Howard Hughes Medical Institute, and his team played an intimate role in developing the new technology for DNA screening for colon cancer. They discovered a specific DNA change, methylation of the vimentin gene, which takes place in colon cancers, and then developed techniques for sensitively detecting this change in DNA shed from colon cancers in the stool. Their technology has been licensed by EXACT Sciences Corporation for commercial development and expanded to include a larger panel of genes.

"This is true translational research, bringing a discovery from the laboratory to the patient care setting," says Li Li MD, PhD, the study's basic investigator, family medicine physician at UH Case Medical Center and Associate Professor at Case Western Reserve University School of Medicine. "Information gained from this study may have significant and immediate implication for the clinical practice of screening and primary prevention of colon cancer."

The five-year study aims to recruit 1,600 patients who are scheduled for screening colonoscopy at UH Case Medical Center and UH community-based practices. Researchers will explore sDNA's efficacy in detecting large polyps, specifically advanced adenomas, which have a higher likelihood of progression to colorectal cancer.

The study is funded as part of the National Cancer Institute's Specialized Program of Research Excellence (SPORE) in Gastrointestinal (GI) Cancers award to Case Western Reserve University School of Medicine. The $11.3 million SPORE grant focuses on translational research aimed at reducing the incidence and deaths from colon cancers and from cancers of the esophagus.

"Among our guiding principles is to pursue and implement breakthrough medical advancements and practices to deliver
'/>"/>

Contact: Alicia Reale
alicia.reale@uhhospitals.org
University Hospitals Case Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. A new journal where molecular biology meets clinical research
2. Self-assembling nano-fiber gel delivers high concentrations of clinically approved drugs
3. Biochemistry of human physiology in health and disease is focus of updated clinical text
4. New book helps medical students master clinical skills
5. In just 5 years, gene discovery to clinical trial of potential treatment
6. Far-reaching genetics topics to be addressed: 2009 Annual Clinical Genetics Meeting, March 25-29
7. Genome Medicine: Bridging the gap between research and clinical practice
8. 3 new informatics pilot projects to aid clinical and translational scientists nationwide
9. TGen Clinical Research Services at Scottsdale Healthcare and Mayo Clinic study new cancer drug
10. ABC publishes monograph on scientific and clinical research of Sinupret
11. Researchers win award for best clinical paper in orthopedic physical therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ) has announced ... in Automotive Sector 2014-2018" report to their offering. ... market in Automotive Sector to grow at a CAGR ... recognition is the ability of a device to identify ... recognition technology can be 2D-based or 3D-based. It uses ...
(Date:3/24/2015)... Research and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ) ... Recognition Market 2015-2019" report to their offering. ... to grow at a CAGR of 23.5 percent over ... present scenario and the growth prospects of the Global ... the market size, the report considers the revenue generated ...
(Date:3/24/2015)... NexID Biometrics LLC, whose spoof-mitigation technology boosts protection ... beginning of shipments of version 2.0 of its industry ... in Potsdam, N.Y. , is making ... here today at the Walter E. Washington Convention Center. ... boosts the accuracy rate range to 96.5 to 99.5 ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2
... Bethesda, MD FASEB MARC (Minority Access to Research ... The American Society for Bone & Mineral Research (ASBMR) ... 15-19, 2010. These awards are meant to promote ... into the mainstream of the basic science community and ...
... of infants each year have exposure to opioids before ... born with withdrawal symptoms severe enough to require opioid ... with long hospital stays which interferes with maternal/infant bonding. ... has tested a semi-synthetic opioid they say has the ...
... Biochemistry and Scripps Institution of Oceanography at UC San ... about how chemistry influences climate and atmospheric processes. ... Center for Aerosol Impacts on Climate and the Environment ... of aerosol particles and the chemical reactions occurring at ...
Cached Biology News:Drug that helps adults addicted to opioid drugs also relieves withdrawal symptoms in newborns 2Scripps researchers, UCSD chemists to create center devoted to chemistry's influence on climate 2Scripps researchers, UCSD chemists to create center devoted to chemistry's influence on climate 3
(Date:4/16/2015)...  EMD Serono today announced the US biopharmaceutical ... , appointed Alise Reicin , MD, ... Development.  Dr. Reicin brings extensive research and early/late ... Immunology. She is an accomplished pharmaceutical executive with ... President in various capacities across R&D at MSD ...
(Date:4/16/2015)... and MENLO PARK, Calif. ... (OTCQX: DMPI) (DelMar and the Company), a biopharmaceutical ... in new orphan drug indications, today announced that the ... as a clinical trial site for the ongoing, multicenter ... glioblastoma multiforme (GBM), the most common and deadly form ...
(Date:4/16/2015)... 2015  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO ... DCVax® personalized immune therapies for cancer, announced today ... Cancer Immunotherapy Index (LCINDX), a professional index recently ... field within the biotechnology space.  ... companies" in the immunotherapy space, including 6 big ...
(Date:4/16/2015)... Modality Solutions, a company that delivers ... industries, is pleased to announce its President, Gary ... Cold Chain IQ - Temperature Control Logistics and ... Global Cold Chain Connections, is dedicated to sharing ... pharmaceutical and healthcare supply chains. , Cold ...
Breaking Biology Technology:Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 2Alise Reicin Joins the Biopharmaceutical Business of Merck KGaA, Darmstadt, Germany as Head of Global Clinical Development 3DelMar Pharmaceuticals Adds Fourth Clinical Trial Site in Phase I/II Multicenter Study of VAL-083 for Recurrent Malignant Glioma 2DelMar Pharmaceuticals Adds Fourth Clinical Trial Site in Phase I/II Multicenter Study of VAL-083 for Recurrent Malignant Glioma 3DelMar Pharmaceuticals Adds Fourth Clinical Trial Site in Phase I/II Multicenter Study of VAL-083 for Recurrent Malignant Glioma 4DelMar Pharmaceuticals Adds Fourth Clinical Trial Site in Phase I/II Multicenter Study of VAL-083 for Recurrent Malignant Glioma 5NW Bio Included In New Index Of The "Top 25 Cancer Immunotherapy Companies" 2NW Bio Included In New Index Of The "Top 25 Cancer Immunotherapy Companies" 3Modality Solutions Gary Hutchinson Named Columnist for Cold Chain IQ 2Modality Solutions Gary Hutchinson Named Columnist for Cold Chain IQ 3
... a new nanomaterial that can "steer" electrical currents. The ... reconfigure its internal wiring and become an entirely different ... are built smaller and smaller, the materials from which ... and begin to be controlled by quantum mechanical phenomena. ...
... ultra-thin sheets of carbon, just one atom thick, whose ... Physics. The seemingly simple material is graphene, ... applications, from electronic devices to high-performance composite materials. ... internal structure at all, it offers an abundance of surface ...
... Blood Corporation (NYSE: CO ) ("CCBC" or "the ... today announced that the Company will hold its annual general meeting ... China Tower, 1 Garden Road, Central, Hong Kong, at 9:00 p.m. ... Time on December 19, 2011).   Shareholders of record ...
Cached Biology Technology:Could a computer one day rewire itself? 2Frustration inspires new form of graphene 2China Cord Blood Corporation to Hold Annual General Meeting in Hong Kong on December 19, 2011 2
... Nonanoyl-N-methylglucamide ... properties. Can be readily removed by ... Purity: ≥98% by HPLC. ... nm): 2 O. CMC 19 ...
...
...
... Tecans MiniPrep series of robotic workstations ... The MiniPrep is the ideal automation ... automation of routine laboratory procedures, improving throughput, ... based Gemini for MiniPrep software allows you ...
Biology Products: