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New clinical data shows chromium picolinate improves cognitive function
Date:12/13/2007

ease communication between brain cells while chromium picolinate increases glucose metabolism.

The results of this clinical study support emerging research that shows chromium has direct effects on cognitive function, said James Komorowski, M.S., Vice President of Scientific Affairs at Nutrition 21. PS and DHA already have established associations with improved cognitive function and we are pleased to see the current findings substantiate the inclusion of chromium picolinate as a key ingredient in Core4Life Advanced Memory Formula.

About the Study

The randomized, double-blind, placebo-controlled study measured whether supplementation with chromium picolinate over a 12-week period might improve cognitive function in 21 adults aged 65 years and older with early memory decline. Study participants were asked to learn a list of words presented over several learning trials and, after a delay, were asked to remember the words. Those receiving the chromium picolinate supplement showed a trend for reduced interference from irrelevant words on the memory task (p = 0.12). In addition, on another task assessing fine motor control and speed, the subjects receiving chromium picolinate exhibited enhanced motor speed relative to those receiving placebo (p = 0.16).

Another component of the study measured brain activity. Functional magnetic resonance imaging (fMRI) scans were performed while subjects were working on a demanding cognitive task that involved holding in mind and manipulating information. Preliminary results from the fMRI scans of individuals from the chromium picolinate group and from the placebo group showed that the subjects receiving the active supplement exhibited greater activity in left frontal and left parietal cortices, areas of the brain associated with working memory. The subjects receiving placebo showed no such change.

At the completion of the study, chromium to creatinine ratios were significantly elevated in
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Contact: Maryrose Lombardo
mlombardo@nutrition21.com
914-701-4525
Nutrition 21  
Source:Eurekalert

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