Navigation Links
New class of biomolecules triggered in response to respiratory virus infection
Date:10/26/2010

For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal's cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.

RNA (ribonucleic acid) contains information transcribed from the cell's instruction manual, its DNA. The best known of these RNAs translate sections of DNA code into building blocks for proteins.

Most studies of how animals' cells respond to virus infection typically look at protein-coding genes, which produce germ-fighting or inflammation-producing substances. However, mammalian cells also transcribe thousands of other RNAs that don't code for proteins.

"The role of most of these non-protein-coding RNAs remains an enigma," noted lead author of the study Dr. Xinxia Peng, a computational research scientist in the Department of Microbiology, University of Washington (UW) School of Medicine in Seattle. Dr. Michael Katze, UW professor of microbiology, directed the project. Katze heads the Center for Systems and Translational Research on Infectious Disease (STRIDE).

"Some attention," Katze said, "has been given to small RNAs, like microRNAs, in host-virus interactions, but now it's becoming apparent that many long-non-protein coding RNAs bigger than 200 nucleotides are also biologically important."

Researchers are learning that long non-protein-coding RNAs have a wide variety of functions. A few examples are modifying chromosomes, regulating genes, influencing cell structure, and serving as precursors for small RNAs and microRNAs, which are involved in virus-host interactions.

The library of RNA transcripts inside of a cell is called its transcriptome, and is a reflection of gene activity. Many different RNAs can be read from a single gene. That is why a transcriptome contains much more complex instructions than seems
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

0

GOOD

Page: 1 2 3 4

Related biology news :

1. Why your boss is white, middle-class and a show-off
2. New research shows how gene function drives natural selection in important class of genetic elements
3. Researchers create new class of fluorescent dyes to detect reactive oxygen species in vivo
4. CSHL scientists find a new class of small RNAs and define its function
5. New discovery may lead to new class of allergy drugs
6. Scientists uncover new class of non-protein coding genes in mammals with key functions
7. Compounds could be new class of cancer drugs
8. Study says middle class coral reef fish feel the economic squeeze
9. Reducing animal experiments through top-class research
10. Genetic switch potential key to new class of antibiotics
11. Nutrition experts propose new class of low-sugar drinks to help stem obesity and diabetes epidemics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New class of biomolecules triggered in response to respiratory virus infection
(Date:5/17/2013)... all ages will celebrate the science and technology ... daily lives during the inaugural Atlanta Science Festival, ... from local museums, corporations, K-12 schools and universities, ... events for children and adults at venues across ... , The annual Atlanta Science Festival is ...
(Date:5/17/2013)... of American Societies for Experimental Biology (FASEB) released a ... (NIH) funding trends highlighting the devastating impact of sequestration ... FASEB analysis follows a May 15th Senate Appropriations Committee ... testified that the $1.6 billion cut the agency sustained ... substantial impact on the scientific community." , According ...
(Date:5/16/2013)... HOUSTON African-American adults living closer to a fast ... than those who lived further away from fast food, ... Anderson Cancer Center, and this association was particularly strong ... new study published online in the American Journal ... residential proximity to a fast food restaurant, and among ...
Breaking Biology News(10 mins):First Atlanta Science Festival set for 2014 2Body mass index of low income African-Americans linked to proximity of fast food restaurants 2Body mass index of low income African-Americans linked to proximity of fast food restaurants 3
... microbes, tiny organisms that do big jobs in our environment, ... and possible extinction but may also play a key role ... published this week in the Proceedings of National Academy ... Jones described how they used a mathematical model and molecular ...
... - March 17, 2010) - Syngenta Crop Protection ... with Innovotech (TSX VENTURE:IOT), a Canadian biotechnology product ... trials in North America on the new plant ... this year Innovotech and Syngenta entered into a ...
... PITTSBURGH, MARCH 22, 2010 -- Significant numbers of today,s ... percent) say they were discouraged from pursuing a STEM ... in their lives, according to a new Bayer Corporation ... them as the leading place in the American education ...
Cached Biology News:Dormant microbes promote diversity, serve environment 2US women and minority scientists discouraged from pursuing STEM careers, national survey shows 2US women and minority scientists discouraged from pursuing STEM careers, national survey shows 3
(Date:5/16/2013)... 16, 2013 The Stirling Ultracold ... Cooling, Inc., Athens, OH, USA, won the Outstanding New ... International Society for Biological and Environmental Repositories (ISBER) at ... to one product annually, recognizes the company’s development and ... freezer. The award was presented to Global Cooling’s ...
(Date:5/16/2013)... Vernon Hills, Ill. (PRWEB) May 16, 2013 ... including benchtop and portable models, from Cole-Parmer is ... professionals. The enhanced line includes: , The new ... that are true workhorses in the lab. They ... superior serum and plasma specimen separation. Their standard ...
(Date:5/16/2013)... May 16, 2013  The registration deadline has been ... Officers (ABFO) 2013 National Conference, the premier conference for ... 28-31 at the Hilton San Diego Bayfront. ... year,s conference and want to make sure as many ... Brandi Roberts , Chief Financial Officer ...
(Date:5/16/2013)... 16, 2013 Reportlinker.com announces ... is available in its catalogue: ... Analysis: Therapeutic Proteins – Biosimilars, Biobetters ...   Product ... The new Competitive Intelligence Report Therapeutic ...
Breaking Biology Technology:Stirling Ultracold Ultra-Low Freezer Wins 2013 Outstanding New Product Award at International Biorepository Conference, Sydney, Australia 2Cole-Parmer Offers Enhanced Selection of Centrifuges 2Registration Extended Until May 22 for Association of Bioscience Financial Officers (ABFO) 2013 National Conference -- San Diego 2Registration Extended Until May 22 for Association of Bioscience Financial Officers (ABFO) 2013 National Conference -- San Diego 3Registration Extended Until May 22 for Association of Bioscience Financial Officers (ABFO) 2013 National Conference -- San Diego 4Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 2Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 3Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 4Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 5Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 6Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 7Competitor Analysis: Therapeutic Proteins - Biosimilars, Biobetters & Biosuperiors 8
... Access, Inc. announces the appointment of Joe Alfrey ... Access organization with that of its joint venture ... gives clients in Southwestern US and Mexico access ... and mission-critical managed services. (Logo:   ...
... WOODLANDS, Texas, Oct. 7 US Oncology, ... uniting the largest cancer treatment and research network ... results for the third quarter of fiscal 2010 ... http://photos.prnewswire.com/prnh/20100517/DA06089LOGO ) (Logo:   http://www.newscom.com/cgi-bin/prnh/20100517/DA06089LOGO ) ...
... VIEW, Calif., Oct. 7 VIVUS, Inc. (Nasdaq: ... drug candidate, are highlighted in six poster presentations at the ... October 8-12, 2010 in San Diego, California. Following ... Society 28th Annual Scientific Meeting at The San Diego Convention ...
Cached Biology Technology:Castle Access Names New Managing Director 2Castle Access Names New Managing Director 3US Oncology to Report 2010 Third Quarter Operating Results 2Data on VIVUS' QNEXA to be Presented in Six Posters at The Obesity Society's Annual Meeting 2Data on VIVUS' QNEXA to be Presented in Six Posters at The Obesity Society's Annual Meeting 3Data on VIVUS' QNEXA to be Presented in Six Posters at The Obesity Society's Annual Meeting 4