Navigation Links
New class of biomolecules triggered in response to respiratory virus infection
Date:10/26/2010

For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal's cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.

RNA (ribonucleic acid) contains information transcribed from the cell's instruction manual, its DNA. The best known of these RNAs translate sections of DNA code into building blocks for proteins.

Most studies of how animals' cells respond to virus infection typically look at protein-coding genes, which produce germ-fighting or inflammation-producing substances. However, mammalian cells also transcribe thousands of other RNAs that don't code for proteins.

"The role of most of these non-protein-coding RNAs remains an enigma," noted lead author of the study Dr. Xinxia Peng, a computational research scientist in the Department of Microbiology, University of Washington (UW) School of Medicine in Seattle. Dr. Michael Katze, UW professor of microbiology, directed the project. Katze heads the Center for Systems and Translational Research on Infectious Disease (STRIDE).

"Some attention," Katze said, "has been given to small RNAs, like microRNAs, in host-virus interactions, but now it's becoming apparent that many long-non-protein coding RNAs bigger than 200 nucleotides are also biologically important."

Researchers are learning that long non-protein-coding RNAs have a wide variety of functions. A few examples are modifying chromosomes, regulating genes, influencing cell structure, and serving as precursors for small RNAs and microRNAs, which are involved in virus-host interactions.

The library of RNA transcripts inside of a cell is called its transcriptome, and is a reflection of gene activity. Many different RNAs can be read from a single gene. That is why a transcriptome contains much more complex instructions than seems
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Why your boss is white, middle-class and a show-off
2. New research shows how gene function drives natural selection in important class of genetic elements
3. Researchers create new class of fluorescent dyes to detect reactive oxygen species in vivo
4. CSHL scientists find a new class of small RNAs and define its function
5. New discovery may lead to new class of allergy drugs
6. Scientists uncover new class of non-protein coding genes in mammals with key functions
7. Compounds could be new class of cancer drugs
8. Study says middle class coral reef fish feel the economic squeeze
9. Reducing animal experiments through top-class research
10. Genetic switch potential key to new class of antibiotics
11. Nutrition experts propose new class of low-sugar drinks to help stem obesity and diabetes epidemics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New class of biomolecules triggered in response to respiratory virus infection
(Date:12/22/2014)... 2014 Holiday Season may be the brightest ever for ... the long anticipated floodgates for consumer biometrics may finally ... phones, tablets, and wearable mobile devices that incorporate biometrics ... with nearly 4.8 billion biometric devices by 2020.   ...
(Date:12/17/2014)... Dec. 15, 2014 Research and Markets ( ... "Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor ... http://photos.prnewswire.com/prnh/20130307/600769 Based on ... Samsung introduces for the first time a fingerprint sensor ...
(Date:12/17/2014)... 2014  Automation is fundamentally transforming the travel experience and ... Over the past decade, ePassports, biometric readers, and secure ... through border control via eGates and Automated Passport Control ... and land borders across the globe. ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... patient survives after a kidney transplant could depend on where ... research from the University of Florida shows. The shorter ... are likely to live. A combination of center-related factors could ... candidates. The UF study is the first to analyze ...
... as a child catching the itchy red rash, chicken pox. ... and was responsible for nearly 4 million cases each year, ... vaccine introduced in 1995 reduced that number by 83 percent. ... pox, the varicella zoster virus may still be present in ...
... eukaryotic cells, is a workhorse that varies remarkably little ... the cytoskeleton, actin assembles into networks of filaments that ... functions, from cell motility and division, to vesicle and ... study in the current issue of Developmental Cell ...
Cached Biology News:Shorter wait means longer life for kidney transplant candidates 2Shorter wait means longer life for kidney transplant candidates 3Childhood chicken pox could affect oral health years later 2A budding role for a cellular dynamo 2
(Date:1/23/2015)... , Jan. 23, 2015  Array BioPharma Inc. (NASDAQ: ... a definitive agreement with Novartis Pharma AG to acquire ... in Phase 3 development.  This agreement is conditional on the ... (GSK) on April 22, 2014, which are expected to close ...
(Date:1/22/2015)... Bedford, NH (PRWEB) January 22, 2015 ... offers a table top laboratory homogenizer, the PandaPLUS 2000, ... nanoparticles, nanodispersions, nanoemulsions , and cell disruption . ... processing dairy products, fruit juices, liquid food, food additives ...
(Date:1/22/2015)... January 22, 2015 Crystal Diagnostics (CDx) Xpress ... it has received AOAC-PTM Certifications for the six non-O157 Shiga ... O145; collectively referred to as STEC or the “Big-6”) as ... forming unit (cfu) per 325 g of raw ground beef ...
(Date:1/22/2015)... January 22, 2015 Selexis SA, a ... Research Cell Banks (RCBs) used for drug discovery to ... Banks will include Next-Generation Sequencing (NGS) data ... de-risks biologic manufacturing by ensuring the integrity of the ...
Breaking Biology Technology:Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 2Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 3Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 4Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 5Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 6Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 7GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2
... Cancer Drugs and Cost Savings Driving Demand for ... Continuous Infusion of Chemotherapy, ... INHI; INHIW; INHIU), the leading provider of,ambulatory infusion pump services ... of 2007. InfuSystem,Holdings, results include results of operations for InfuSystem, ...
... interviews Said,Darwazah, CEO, and Bassam Kanaan, CFO, discuss ... are expecting from the company,in 2008. The interviews, ... http://www.cantos.com ., It,s free to view. All ... . Cantos.com, the online financial broadcaster,features in-depth interviews, ...
... modifications, thereby providing scientists with a tool to ... to drug discovery. However, this sophisticated technology can ... engineered pathogens. New research published in the online ... tools could become a vital resource for detecting ...
Cached Biology Technology:InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 2InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 3InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 4InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 5InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 6InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 7InfuSystem Holdings Provides Business Update and Comments on Fourth Quarter 2007 Financial Results 8On the trail of rogue genetically modified pathogens 2
Vybrant® Multidrug Resistance Assay Kit...
... Platypus Contact Printing Kit contains choice ... with series of 100 / 200 micron ... or 200 um x 10 mm lines, ... 20, 40 or 60 nm and pitch ...
Request Info...
Sterile glass 5 mm beads that make spreading bacterial and yeast cultures easy. Can be washed, autoclaved and reused....
Biology Products: