Navigation Links
New 'chemically-sensitive MRI scan' may bypass some invasive diagnostic tests in next decade
Date:8/20/2007

A new chemical compound which could remove the need for patients to undergo certain invasive diagnostic tests in the future has been created by scientists at Durham University.

Research published in the academic journal, Chemical Communications, reveals that this new compound could be used in a chemically-sensitive MRI scan to help identify the extent of progression of diseases such as cancer, without the need for intrusive biopsies.

The researchers, who are part of an Engineering and Physical Sciences Research Council (EPSRC) funded group developing new ways of imaging cancer, have created a chemical which contains fluorine. It could, in theory, be given to the patient by injection before an MRI scan. The fluorine responds differently according to the varying acidity in the body, so that tumours could be highlighted and appear in contrast or light up on the resulting scan.

Professor David Parker of Durham Universitys Department of Chemistry explained: There is very little fluorine present naturally in the body so the signal from our compound stands out. When it is introduced in this form it acts differently depending on the acidity levels in a certain area, offering the potential to locate and highlight cancerous tissue.

Professor Parkers team is the first to design a version of a compound containing fluorine which enables measurements to be taken quickly enough and to be read at the right frequency to have the potential to be used with existing MRI scanners, whilst being used at sufficiently low doses to be harmless to the patient.

Professor Parker continued: We have taken an important first step towards the development of a selective new imaging method. However, we appreciate that there is a lot of work to do to take this laboratory work and put it into practice. In principle, this approach could be of considerable benefit in the diagnosis of diseases such as breast, liver or prostate cancer.

Durham University has filed a patent on this new approach and is looking for commercial partners to help develop the research. Professor Parker and his team believe that molecules containing fluorine could be used in mainstream MRI diagnoses within the next decade.

Chris Hiley, Head of Policy and Research Management at The Prostate Cancer Charity, said: This is interesting work. The researchers are still some way from testing how this new idea might work in people but they are dealing with a knotty and important problem. In prostate cancer in particular more research is needed into cancer imaging as current techniques need improving.

This development could have applications in many other cancers too. Once transferred from the lab to the bedside this research has potential to help show exactly where cancer may be in the body. This would add certainty to treatment decisions and improve monitoring of cancer progress. Looking even further into the future it could even have some use in improving diagnosis.


'/>"/>
Contact: Jane Budge
media.relations@durham.ac.uk
01-913-346-075
Durham University
Source:Eurekalert

Related biology news :

1. PET/MRI scans may help unravel mechanisms of prenatal drug damage
2. Brain Scans Reveal How Gene May Boost Schizophrenia Risk
3. Whole-body MRI Takes Less Than 20 Min To Scan A Patients Entire Body For Cancer Spread To Bone
4. Next Generation Body Scanner Launched By The University Of Manchester
5. Brain Scan Study of Smokers Reveals Signature of Craving
6. New gene scanning technology marks a major advance in disease research
7. Researchers use brain scans to predict behavior
8. Retinal scans eyed for New Mexico show cattle
9. New brain scan technology could save babies lives
10. 3-D ultrasound scanner could guide robotic surgeries
11. Using brain scans, researchers find evidence for a two-stage model of human perceptual learning
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/14/2016)... NXTD ) ("NXT-ID" or the "Company"), ... the airing of a new series of commercials on Time ... 21 st .  The commercials will air on Bloomberg TV, ... the Street show. --> NXTD ) ("NXT-ID" or ... market, announces the airing of a new series of commercials ...
(Date:3/11/2016)... 2016 http://www.apimages.com ) - --> ... available at AP Images ( http://www.apimages.com ) - ... to produce the new refugee identity cards. DERMALOG will be unveiling ... in Hanover next week.   --> ... used to produce the new refugee identity cards. DERMALOG will be ...
(Date:3/10/2016)... , March 10, 2016 ... market research report "Identity and Access Management Market by ... Compliance, and Governance), by Organization Size, by Deployment, by ... published by MarketsandMarkets, The market is estimated to grow ... Billion by 2020, at a Compound Annual Growth Rate ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... OXFORD, England , May 23, 2016 ... Wednesday, May 25 th at 10:15 a.m. ET before ... about the role genetically engineered mosquitos can play in controlling ... known carrier of the Zika virus.      (Logo: ... genetically engineered male mosquito with a self-limiting gene. Trials in ...
(Date:5/23/2016)... , ... May 23, 2016 , ... ... management solutions and services based in Aurora, Ohio, has broken ground on a ... in the Research Triangle Park area, this new location solidifies a commitment to ...
(Date:5/22/2016)... ... May 22, 2016 , ... Doctors in Rome say micronutrients found ... cancer, malignant mesothelioma. Surviving Mesothelioma has just posted an article on the new research. ... Rome’s Department of Clinical Sciences and Translational Medicine evaluated more than 150 studies on ...
(Date:5/20/2016)... , ... May 20, 2016 , ... Kablooe Design, a ... companies, today announced its official 25th anniversary of the business. “We have worked hard ... grateful to our customers for the privilege and honor of serving their product design ...
Breaking Biology Technology: