Navigation Links
New cell type offers immunology hope
Date:6/14/2011

A team of Australian scientists has discovered a new type of cell in the immune system.

The new cell type, a kind of white blood cell, belongs to a family of T-cells that play a critical role in protection against infectious disease.

Their findings could ultimately lead to the development of novel drugs that strengthen the immune response against particular types of infectious organisms.

It is also potentially significant for many other important diseases including allergies, cancer and coronary artery disease.

The research team includes Dr Adam Uldrich and Professor Dale Godfrey from the University of Melbourne, Dr Onisha Patel and Professor Jamie Rossjohn from Monash University and Professor Mark Smyth from the Peter MacCallum Cancer Institute.

The discovery, published in the international journal Nature Immunology, is a fundamental advance in understanding the different components of the immune system and how this system casts a net wide enough to catch all kinds of different infectious organisms.

Typically, when the body is threatened with bacterial or viral infection, molecules called T-cell receptors interact with protein fragments (called peptides) from the bacterium or virus, triggering the immune response. This process has been widely studied and leads to the killing of microbes and protection against severe infection.

While the immune system is known to focus on proteins from viruses and bacteria, some T-cells in the immune system (known as NKT cells) can recognise lipid-based, or fatty, molecules. As such, there is great enthusiasm for the potential of these lipid-sensing T-cells in the development of novel vaccines. This team have identified a new type of NKT cell that can specifically target lipids found in the cell walls of bacteria, including Mycobacteria.

Professor Dale Godfrey from the University of Melbourne said the discovery is significant and opens the door
'/>"/>

Contact: Rebecca Scott
rebeccas@unimelb.edu.au
61-383-440-181
University of Melbourne
Source:Eurekalert

Page: 1 2

Related biology news :

1. Worm genome offers clues to evolution of parasitism
2. Advance offers revolution in food safety testing
3. Light pollution offers new global measure of coral reef health
4. Rong Li Lab offers insight into adaptive ability of cells
5. International public-private partnership offers new paradigm for medicinal chemistry
6. UC Davis discovery offers hope for treating kidney cancer
7. New paper offers key insights into how new species emerge
8. Study offers clues to beating hearing loss
9. Fighting global warming offers growth and development opportunities
10. Brown-led team offers first look at how bats land
11. Star Trek-like technology offers noninvasive monitor for patients and athletes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Dec. 18, 2014   LaunchKey , the first ... post-password and Internet of Things era, today announced the ... venture round was led by Metamorphic Ventures with participation ... Partners, VegasTechFund, and others.  LaunchKey has raised $4 million ... expand its team and bring LaunchKey to market in ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB ... Good Clinical Practices (GCP) audit to confirm its ... (FDA) regulations. This accomplishment enables HITLAB to conduct ... utilizing the highest principles for patient safety and ... improve global healthcare access, quality, and delivery with ...
(Date:12/17/2014)... 16, 2014  Automation is fundamentally transforming the ... than at international borders. Over the past decade, ... allowed veteran travelers to self process through border ... Kiosks at an increasing number of airports, seaports, ... According to Maxine Most , Principal ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... of vocal mimicry, researchers from the Wildlife Conservation Society (WCS) ... cat species imitating the call of its intended victim: a ... the first recorded instance of a wild cat species in ... extraordinary behavior was recorded by researchers from the Wildlife Conservation ...
... leave the pediatrician,s office if your child has strep ... treatment. A novel application for applying DNA "nanobarcodes" ... and more accurately determine what,s causing a patient,s acute ... R. Hartman, a Cornell University PhD candidate in Biological ...
... Elsevier, a world leader in health care, medical publishing ... Legacy Interactive, announced today the release of Top Doc, ... designed to let medical students, residents and junior faculty ... and Legacy Interactive developed the app,s interactive format to ...
Cached Biology News:Wildlife Conservation Society finds wild cat mimicking monkey calls 2Instant testing for sore throats wins CIMIT prize 2Instant testing for sore throats wins CIMIT prize 3Instant testing for sore throats wins CIMIT prize 4Elsevier and Legacy Interactive partner to launch iPhone app 2
(Date:12/17/2014)... York, NY (PRWEB) December 16, 2014 ... significant changes since 2013, which is why IBISWorld updated ... this industry continues to benefit from an intensified focus ... the proposal for new emission standards for power plants ... industry operators. According to IBISWorld Industry Analyst Sarah Kahn, ...
(Date:12/17/2014)... Washington, USA (PRWEB) December 16, 2014 ... Baum, manager at Philipps- Universität Marburg’s Department of ... and photonics, in the newly released SPIE ... “And never be too shy to ask questions.” ... (science, technology, engineering, and mathematics) occupations ranging from ...
(Date:12/17/2014)... (PRWEB) December 17, 2014 Ipsen ... IPN; ADR: IPSEY), today announced that ... to as Somatuline®) was approved by the U.S. ... of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in adult patients ... or metastatic disease to improve progression-free survival (PFS). ...
(Date:12/17/2014)... December 17, 2014 This report ... Quartz Tubing industry. For an overview analysis, the ... application, industry chain structure, industry overview, policy analysis, ... tubing industry has witnessed rapid development with ... of acquisitions. This report mentions quartz tubing upstream ...
Breaking Biology Technology:Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 82020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2
... Company to Provide Business Systems and Technology Support to NIH Office ... ... 5 SRA International, Inc.,(NYSE: SRX ), a leading provider ... has been,awarded a competitive task order to provide a broad range ...
... Oct. 5 The Coalition for a,Competitive Pharmaceutical ... Food and Drug Administration,s announcement regarding its,"Generic Initiative ... employers, insurers, and policymakers grappling with,how to manage ... FDA,and Congress continue to focus on ways to ...
... Lexicon,Pharmaceuticals, Inc. (Nasdaq: LXRX ) today announced ... executive officer, will present,at the BIO InvestorForum at The ... 2007 at 11:00 a.m. Pacific Time. A live ... website at http://www.lexpharma.com . An archived version of ...
Cached Biology Technology:National Institutes of Health Awards $25.5M Contract to SRA 2CCPM Issues Statement on FDA's GIVE Initiative 2Lexicon Pharmaceuticals to Present at Bio InvestorForum 2
... The RapidCycler is the first instrument ... reactions and is used by thousands of ... Roche LightCycler Capillary tubes which are ideally ... their thin walls and extremely high surface-area-to-volume ...
... of human cullin genes (CUL-1, -2, -3, -4a, -4b, ... Cullin-3 is proposed to be a part of E3 ... E and targets it for ubiquitination, which leads to ... of cdk2, which leads the cell to S phase. ...
Yellow oily liquid. Contains 85% Drakeol 5NF, 15% Arlacel A (mannide monooleate emulsifier). Heat sterilized. Contains zero colony forming units/ml. ...
... LED produces output at 470 nm; includes interface ... S2000 or installed into rack or desktop boxes ... Source is an LED that produces either pulsed ... blue region -- for fluorescence measurements. The source ...
Biology Products: