Navigation Links
New cancer gene discovered
Date:10/13/2009

A new cancer gene has been discovered by a research group at the Sahlgrenska Academy at the University of Gothenburg, Sweden. The gene causes an insidious form of glandular cancer usually in the head and neck and in women also in the breast. The discovery could lead to quicker and better diagnosis and more effective treatment.

The study is published today in the prestigious scientific journal Proceedings of the National Academy of Sciences (PNAS).

The cancer caused by this new cancer gene is called adenoid cystic carcinoma and is a slow-growing but deadly form of cancer. The research group can now show that the gene is found in 100% of these tumours, which means that a genetic test can easily be used to make a correct diagnosis.

"Now that we know what the cancer is down to, we can also develop new and more effective treatments for this often highly malignant and insidious form of cancer," says professor Gran Stenman, who heads the research group at the Lundberg Laboratory for Cancer Research at the Sahlgrenska Academy. "One possibility might be to develop a drug that quite simply turns off this gene."

The newly discovered cancer gene is what is known as a fusion gene, created when two healthy genes join together as a result of a chromosome change.

"Previously it was thought that fusion genes pretty much only caused leukaemia, but our group can now show that this type of cancer gene is also common in glandular cancer," says Stenman.

One of the two genes that form the fusion gene is known as MYB. Among other things, this gene controls cell growth and makes sure that the body gets rid of cells that are no longer needed. It has long been known to be a highly potent cancer gene in animals, but for a long time there was no evidence of the gene being involved in the development of tumours in humans.

"We suggested back in 1986 that the MYB gene might be involved in this form of cancer, but it's on
'/>"/>

Contact: Professor Goran Stenman
goran.stenman@llcr.med.gu.se
46-313-422-922
University of Gothenburg
Source:Eurekalert

Page: 1 2

Related biology news :

1. Loss of tumor supressor gene essential to transforming benign nerve tumors into cancers
2. Magnetic nanotags spot cancer in mice earlier than methods now in clinical use
3. Survivors of childhood cancer less likely to marry
4. American Association for Cancer Research to honor leading researchers at breast cancer symposium
5. Study finds 231 new genes associated with head and neck cancer
6. UNC awarded Cancer Genome Atlas grant
7. Study in Spain and Romania confirms radon as second leading cause of lung cancer
8. Stimulus-funded university research addressing issues from climate change to cancer, creating jobs and training a new generation of scientists
9. Research network based at University of Toronto gets $5 million boost to speed up cancer detection
10. Shedding light on cancer cells
11. Diabetes drug shows promise in fighting lethal cancer complication
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... stabilize or even improve the state of fisheries ... in the Mediterranean has deteriorated over the past ... fish species reported in the Cell Press journal ... call for stringent monitoring of Mediterranean fishing activities, ... plans in Mediterranean waters. , Their data show ...
(Date:7/10/2014)... Poor peepers are a problem, even if you are ... an imperious predator, scouring the shallow waters for any ... eye exam by Yale University scientists, you,re reduced to ... night. , Such is the lot of the giant ... new paper by Yale paleontologists, published in the journal ...
(Date:7/10/2014)... controversy centres around a family of enzymes known as ... group in their active site. At the centre of ... becomes oxidised (ferryl) when a reacting heme is in ... has remained unanswered for decades is whether this oxidation ... group (OH). Resolving this fundamental question has implications for ...
Breaking Biology News(10 mins):Mediterranean fish stocks show steady decline 2Extinct sea scorpion gets a Yale eye exam, with surprising results 2Neutron crystallography solves long-standing biological mystery 2Neutron crystallography solves long-standing biological mystery 3
... record of oxygen concentration in the earth's atmosphere shows that ... gave mammals the evolutionary boost they needed to dominate the ... and lead author of a paper published Sept. 30 ... have measured the abundance of carbon 13, a byproduct ...
... have learned how to selectively shut down a flyweight-sized ... that may help doctors better understand cancer, birth defects ... be reported this week in the online Proceedings of ... of genetic material called microRNAs. , Once thought to ...
... A team of researchers from the Department of Biochemistry ... the Universitat Autònoma de Barcelona has discovered that tetanus ... a therapy against psychological disorders such as depression, anxiety ... disorders such as Parkinson's disease. , Tetanus toxin is ...
Cached Biology News:Oxygen increase caused mammals to triumph, researchers say 2Micro-molecule plays big role in birth defects 2Tetanus toxin found to have therapeutic properties 2
(Date:7/10/2014)... (PRWEB) July 10, 2014 Understanding the ... channel-expressing cell lines, and the gap that currently exists ... that expand its industry-leading portfolio of validated ion channel ... ion channel-expressing cell lines, as ion channels control many ... control this activity creates the potential to treat a ...
(Date:7/10/2014)... July 10, 2014 Robert Harman, DVM, Founder ... company, is proud to announce the relaunch of his highly ... a new series called “ What are Stem Cells ?” ... honest and straightforward foundation in the basics of stem cell ... on the right type of treatment when considering regenerative medicine. ...
(Date:7/10/2014)... July 10, 2014 Senior supply chain ... professional associations, addressed the challenges of “Reducing Cost, Lead ... Industries” through strategic sourcing. Describing the partnership of the ... Supply Chain Management Institute ( SCMI) of the ... June 24 at the Kroc Institute of Peace and ...
(Date:7/10/2014)... 10, 2014  Kainos Capital, a firm specializing in ... that it has acquired the Slim-Fast brand from Unilever. ... Terms of the transaction were not disclosed. ... business that markets ready-to-drink shakes, powders, bars and snacks ... and in the United Kingdom ...
Breaking Biology Technology:Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4Kainos Capital Acquires Slim-Fast From Unilever 2
... genetics,(Nasdaq: DCGN ) today expressed its enthusiastic ... bill that, many years in the,making, is now ... be signed,promptly by President Bush. GINA would provide ... prohibiting discrimination against,individuals in matters of employment or ...
... April 25 Beckman,Coulter, Inc. (NYSE: BEC ... a quarterly dividend payout of seventeen cents ($0.17) ... 23, 2008 to all stockholders of,record on May ... payout of dividends., (Logo: http://www.newscom.com/cgi-bin/prnh/20031202/BECLOGO ), ...
... BERLIN, April 25 Processes and products based ... the chemical industry in a wide range of ... the field of industrial,biotechnology in Germany will be ... Bioprocessing (April 27-30, 2008) in Chicago, Illinois.,The panel ...
Cached Biology Technology:deCODE Lauds Federal Legislation to Ban Discrimination on the Basis of Genetic Information 2deCODE Lauds Federal Legislation to Ban Discrimination on the Basis of Genetic Information 3deCODE Lauds Federal Legislation to Ban Discrimination on the Basis of Genetic Information 4World Congress on Industrial Biotechnology: Germany Home to Top Biotech Research and Investment 2
...
...
...
... is >95%NEN Radiolabeled Ligands\n\nReceptor-related research has long ... new radiolabeled ligands selected to keep pace ... range of products and services for receptor ... state-of-the-art radioligands. If you do not find ...
Biology Products: