Navigation Links
New brain nerve cells key to stress resilience, UT Southwestern researchers find
Date:3/30/2010

DALLAS March 31, 2010 UT Southwestern Medical Center researchers have found new clues that might help explain why some people are more susceptible to stress than others.

In a study of mice, the researchers determined that weeks after experiencing a stressful event, animals that were more susceptible to stress exhibited enhanced neurogenesis the birth of new nerve cells in the brain. Specifically, the cells that these animals produced after a stressful event survived longer than new brain cells produced by mice that were more resilient.

In addition, when researchers prevented neurogenesis in both stress-susceptible and resilient mice, the animals previously susceptible to stress became more resilient.

"This work shows that there is a period of time during which it may be possible to alter memories relevant to a social situation by manipulating adult-generated nerve cells in the brain," said Dr. Amelia Eisch, associate professor of psychiatry at UT Southwestern and senior author of the study, available in the Proceedings of the National Academy of Sciences. "This could eventually lead to a better understanding of why, in humans, there is an enormous variety of responses to stressful situations."

Mice that are susceptible to stress exhibit long-lasting social avoidance and depressive-like behavior after experiencing a stressful event, such as being placed in a cage with a more aggressive mouse. Resilient mice behave more like unstressed control animals. This animal model is commonly used in studies of stress and depression, as understanding the changes in the brain and behavior of the mice can shed light on stress-induced changes in the human brain and in human behavior.

In the study, the brain cells of both groups of mice responded in similar ways after a stressful event. But weeks later, researchers found that mice displaying social avoidance had more nerve cells in a region of the brain called the hippoc
'/>"/>

Contact: LaKisha Ladson
lakisha.ladson@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Invasion of the brain tumors
2. HIV is a double hit to the brain
3. AIDS interferes with stem cells in the brain
4. 60 second test could help early diagnosis of common brain diseases
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Influence of sex and handedness on brain is similar in capuchin monkeys and humans
8. Inside the brain of a crayfish
9. Specific brain protein required for nerve cell connections to form and function
10. Brains timing linked with timescales of the natural visual world
11. Adult brain can change, study confirms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... A sleep-promoting circuit located deep in the primitive brainstem ... by researchers at Harvard School of Medicine and the ... this is only the second "sleep node" identified in ... necessary and sufficient to produce deep sleep. , Published ... study demonstrates that fully half of all of the ...
(Date:9/18/2014)... Worcester, Mass. A novel robotic system that can ... currently being tested as part of a biomedical research ... with the aim of determining if the robot, in ... biopsies faster, more accurate, less costly, and less discomforting ... potential to deliver prostate cancer therapies with greater precision. ...
(Date:9/18/2014)... many times it,s demonstrated, it,s still hard to ... But by using a signaling system called "quorum ... to suit their population. In short, some bacteria ... act accordingly. , Once the population of quorum-sensing ... innocuous to pathogenic, or from unhelpful to helpful. ...
Breaking Biology News(10 mins):No sedative necessary: Scientists discover new 'sleep node' in the brain 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3
... at the University of Liverpool have discovered that the ... million years old and took its present shape about ... in collaboration with the University of Amsterdam and Petrobras, ... taken from two boreholes near the mouth of the ...
... well-fed, clonal organisms in the Caribbean Sea as the ... Pacific, report researchers from the Smithsonian Tropical Research Institute ... shows that if a species could shift from clonal ... for extinction, millions of years later. Closure of the ...
... A study conducted by researchers at Ben-Gurion University of the ... indicates that approximately 16 percent of public health care workers ... regardless of the severity. The study,just published in the ... 1,835 public health workers in Minnesota, Ohio and West Virginia ...
Cached Biology News:Sex in the Caribbean: Environmental change drives evolutionary change -- eventually 21 in 6 health workers won't report in flu pandemic -- study by Ben-Gurion U. researchers 21 in 6 health workers won't report in flu pandemic -- study by Ben-Gurion U. researchers 3
(Date:9/19/2014)... (Nasdaq: ITMN ) today announced that it ... litigation in the Delaware Court of Chancery relating to ... August 22, 2014, among Roche Holdings, Inc., Klee Acquisition ... Memorandum of Understanding, the Company agreed to make certain ... the amendment to the Company,s Schedule 14D-9 to be ...
(Date:9/19/2014)... that use light, rather than electricity, to move ... energy efficiency is a growing concern as chips, ... components of optical circuits light emitters, modulators, ... build. One promising light source for optical chips ... properties when deposited as a single, atom-thick layer. ...
(Date:9/19/2014)... , September 19, 2014 Biotech ... development of emerging drug systems and advanced Laboratory Instrumentation. ... and Company (NYSE: BDX ), Thermo Fisher ... Inc. (NASDAQ: RGDO ), Sangamo Biosciences Inc. ... HOLX) Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI" ...
(Date:9/19/2014)... , September 19, 2014 BioTech ... developments, patents and results of studies and trials.  Companies ... and Company (NYSE: LLY ), Gilead Sciences ... CELG ) and Arena Pharmaceuticals Inc. (NASDAQ: ... in developing prodrug therapeutics for the treatment of cancer, ...
Breaking Biology Technology:InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 2InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 3InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 4InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 5InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 6InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 7InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 8InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 9InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 10InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 11InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 12InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 13InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 14InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 15InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 16InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 17InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 18InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 19Toward optical chips 2Toward optical chips 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 2Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 4Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 5Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 6Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 7Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7
... and pharmaceutical firms are developing a host of ... discovery process, reports Genetic Engineering and Biotechnology ... rely on a combination of high-throughput screening methods, ... an article in the July issue ( http://www.genengnews.com/articles/chitem.aspx?aid=2527 ...
... Lilly,s Structure-Based Drug Discovery Capabilities, INDIANAPOLIS, and SAN ... LLY ) and SGX Pharmaceuticals, Inc. (Nasdaq: SGXP ... merger agreement,providing for the acquisition of SGX in an ... biotechnology company focused on drug,discovery and development in the ...
... , ... St. Louis, MO (PRWEB) July 8, 2008 -– In a new ... describes the process of food biotechnology, as well as the safety and ... on a daily basis make numerous decisions about the food they eat. ...
Cached Biology Technology:Lilly to Acquire SGX Pharmaceuticals 2Lilly to Acquire SGX Pharmaceuticals 3Lilly to Acquire SGX Pharmaceuticals 4Lilly to Acquire SGX Pharmaceuticals 5Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 2Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 3Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 4
... G bind specifically to Fc regions of ... G conjugates are commonly used as affinity ... subtypes from serum, hybridoma ascites fluids, tissue ... reagents are also commonly used to capture ...
... (10 min) assay can detect H2O2 or ... (ADHP). H2O2 oxidizes ADHP in a 1:1 ... (excitation at 530-571 nm, emission at 590-600 ... in a one-step, homogeneous, no wash assay ...
... The Reverse-iT™ One-Step Kit is ... reproducibility in RT-PCR. It has been ... process. The Reverse-iT™ One-Step Kit ... RTases and ABgene®s Thermoprime Plus DNA ...
... for protein pull-down experiments to ... proteins. An order of Sphingobeads ... beads with 10 nmol of ... of the alkyl chain; enough ...
Biology Products: