Navigation Links
New book reviews ancient and modern worlds of RNA
Date:9/28/2010

COLD SPRING HARBOR, N.Y. (Sept. 28, 2010) -- A new book, RNA Worlds: From Life's Origins to Diversity in Gene Regulation, reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.

"[T]he plasticity of RNA stemming from its 2' hydroxyl group and single-stranded nature, which permits diverse folding in contrast to its storage molecule cousin, DNA, continues to fascinate," write the editors, John F. Atkins, Raymond F. Gesteland, and Thomas R. Cech, in the book's preface.

Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA is now known to be a highly versatile molecule that has multiple roles in cells. It can function as an enzyme, scaffold various subcellular structures, and regulate gene expression through a variety of mechanisms, as well as act as a key component of the protein synthesis and splicing machinery. Perhaps most interestingly, increasing evidence indicates that RNA preceded DNA as the hereditary material and played a crucial role in the early evolution of life on Earth.

The early chapters of the book analyze the role of RNA in the first life forms and the appearance of cells. Subsequent chapters examine riboswitches and ribozymes, establishing what the RNA molecule is capable of alone. The book goes on to discuss the evolution of ribosomes and the functions of RNPs, before reviewing the recent work that has revolutionized our understanding of gene regulation by non-coding RNAs, including miRNAs and siRNAs. Also covered are viral RNAs, telomerase RNA, and tools for scientists who work on RNA. Each chapter is written by one or more experts in the field.

The book has just been released by Cold Spring Harbor Laboratory Press, and is essential reading for all molecular biologists and biochemists, as well as chemists interested in RNA technology, information storage, or enzyme catalysis.


'/>"/>

Contact: Ingrid Benirschke
benirsch@cshl.edu
619-275-6021
Cold Spring Harbor Laboratory
Source:Eurekalert  

Related biology news :

1. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
2. Biophysical Reviews makes debut in 2009
3. Reviews of microbial gene language published in special issue of Trends in Microbiology
4. EPA reviews Univ. of Michigan dioxin study
5. New book reviews the structure and function of cell junctions
6. New book reviews research on p53 -- the guardian of the genome -- and its relatives
7. NOAA report reviews ecosystem management in national marine sanctuaries
8. Teleconference Alert: LyondellBasell Reviews Second Quarter 2010 Financial Results
9. Modern genetics vs. ancient frog-killing fungus
10. Genetic based human diseases are an ancient evolutionary legacy
11. 6,000km trip to reveal clues to ancient migration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New book reviews ancient and modern worlds of RNA
(Date:2/4/2016)... , Feb. 4, 2016 The ... apparently one of the most popular hubs of ... MetaHIT and other huge studies of human microbiota, ... past few years, the microbiome space has literally ... biomedical research. This report focuses on biomedical ...
(Date:2/2/2016)... Feb. 2, 2016  BioMEMS devices deployed ... focused on medical screening and diagnostic applications, ... Wearable devices that facilitate and assure continuous ... movement are being bolstered through new opportunities ... signal acquisition coupled with wireless connectivity and ...
(Date:2/2/2016)... 2, 2016  Based on its recent analysis ... recognizes US-based Intelligent Retinal Imaging Systems (IRIS) with ... for New Product Innovation. IRIS, a prominent cloud-based ... America , is poised to set the ... retinopathy market. The IRIS technology presents superior price-performance ...
Breaking Biology News(10 mins):
(Date:2/9/2016)... , ... February 08, 2016 , ... ... testing services, announced today the launch of its revamped and improved website. In ... language service solutions, the redesigned website will better communicate how the company designs ...
(Date:2/9/2016)... ... ... The American Academy of Thermology (AAT) has announced that for the ... Qualification Course for Technicians via a two part webinar on July 30 and August ... of hardware, software, and camera setup/operations, aligns with the in-person member qualification course that ...
(Date:2/9/2016)... , Feb. 9, 2016  DNAtrix, a ... for cancer, announced that its lead product, ... Commission as an orphan medicinal product for ... form of glioma, strikes approximately 25,000 people ... http://photos.prnewswire.com/prnh/20160208/330986LOGO --> ...
(Date:2/9/2016)... 9, 2016 Three-Year Initiative Supports Next ... Take Part in Life-Changing Camp Experiences ... to positively affect the lives of children born with rare diseases, ... SHPG ) is announcing a new initiative designed to positively ... as the future of rare disease care. --> To ...
Breaking Biology Technology: