Navigation Links
New book reviews ancient and modern worlds of RNA
Date:9/28/2010

COLD SPRING HARBOR, N.Y. (Sept. 28, 2010) -- A new book, RNA Worlds: From Life's Origins to Diversity in Gene Regulation, reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.

"[T]he plasticity of RNA stemming from its 2' hydroxyl group and single-stranded nature, which permits diverse folding in contrast to its storage molecule cousin, DNA, continues to fascinate," write the editors, John F. Atkins, Raymond F. Gesteland, and Thomas R. Cech, in the book's preface.

Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA is now known to be a highly versatile molecule that has multiple roles in cells. It can function as an enzyme, scaffold various subcellular structures, and regulate gene expression through a variety of mechanisms, as well as act as a key component of the protein synthesis and splicing machinery. Perhaps most interestingly, increasing evidence indicates that RNA preceded DNA as the hereditary material and played a crucial role in the early evolution of life on Earth.

The early chapters of the book analyze the role of RNA in the first life forms and the appearance of cells. Subsequent chapters examine riboswitches and ribozymes, establishing what the RNA molecule is capable of alone. The book goes on to discuss the evolution of ribosomes and the functions of RNPs, before reviewing the recent work that has revolutionized our understanding of gene regulation by non-coding RNAs, including miRNAs and siRNAs. Also covered are viral RNAs, telomerase RNA, and tools for scientists who work on RNA. Each chapter is written by one or more experts in the field.

The book has just been released by Cold Spring Harbor Laboratory Press, and is essential reading for all molecular biologists and biochemists, as well as chemists interested in RNA technology, information storage, or enzyme catalysis.


'/>"/>

Contact: Ingrid Benirschke
benirsch@cshl.edu
619-275-6021
Cold Spring Harbor Laboratory
Source:Eurekalert  

Related biology news :

1. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
2. Biophysical Reviews makes debut in 2009
3. Reviews of microbial gene language published in special issue of Trends in Microbiology
4. EPA reviews Univ. of Michigan dioxin study
5. New book reviews the structure and function of cell junctions
6. New book reviews research on p53 -- the guardian of the genome -- and its relatives
7. NOAA report reviews ecosystem management in national marine sanctuaries
8. Teleconference Alert: LyondellBasell Reviews Second Quarter 2010 Financial Results
9. Modern genetics vs. ancient frog-killing fungus
10. Genetic based human diseases are an ancient evolutionary legacy
11. 6,000km trip to reveal clues to ancient migration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New book reviews ancient and modern worlds of RNA
(Date:6/23/2017)... and ITHACA, N.Y. , ... and Cornell University, a leader in dairy research, today ... bioinformatics designed to help reduce the chances that the ... the onset of this dairy project, Cornell University has ... for Sequencing the Food Supply Chain, a food safety ...
(Date:5/16/2017)... May 16, 2017  Veratad Technologies, LLC ( www.veratad.com ... age and identity verification solutions, announced today they will ... 2017, May 15 thru May 17, 2017, in ... International Trade Center. Identity impacts the ... in today,s quickly evolving digital world, defining identity is ...
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... and OXFORD, England , Aug. 16, ... consortium for biotech executive search and leadership development, and Virdis ... sectors, have created an exclusive alliance that enables clients to ... "For our clients here in the ... unparalleled access to a diverse population of leadership talent throughout ...
(Date:8/15/2017)... ... August 15, 2017 , ... ... largest Asian exhibitions for analytical and scientific instruments. This year’s symposium, organized by ... Approaches in Mass Spectrometry for Bioanalytical Applications.” This dynamic presentation will discuss novel ...
(Date:8/15/2017)... ... August 15, 2017 , ... Coffea arabica ... biotic and abiotic factors. During this educational webinar, participants will learn about the ... as gain a better understanding of how genomics is important for coffee breeding ...
(Date:8/14/2017)... ... August 14, 2017 , ... The Conference Forum ... which will take place on September 6, 2017 at the Marriott Copley Place in ... of Experimental Medicine, Informatics, and Regulatory Strategy, Pfizer Innovative Research Lab, Pfizer, who leads ...
Breaking Biology Technology: