Navigation Links
New book reviews ancient and modern worlds of RNA
Date:9/28/2010

COLD SPRING HARBOR, N.Y. (Sept. 28, 2010) -- A new book, RNA Worlds: From Life's Origins to Diversity in Gene Regulation, reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.

"[T]he plasticity of RNA stemming from its 2' hydroxyl group and single-stranded nature, which permits diverse folding in contrast to its storage molecule cousin, DNA, continues to fascinate," write the editors, John F. Atkins, Raymond F. Gesteland, and Thomas R. Cech, in the book's preface.

Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA is now known to be a highly versatile molecule that has multiple roles in cells. It can function as an enzyme, scaffold various subcellular structures, and regulate gene expression through a variety of mechanisms, as well as act as a key component of the protein synthesis and splicing machinery. Perhaps most interestingly, increasing evidence indicates that RNA preceded DNA as the hereditary material and played a crucial role in the early evolution of life on Earth.

The early chapters of the book analyze the role of RNA in the first life forms and the appearance of cells. Subsequent chapters examine riboswitches and ribozymes, establishing what the RNA molecule is capable of alone. The book goes on to discuss the evolution of ribosomes and the functions of RNPs, before reviewing the recent work that has revolutionized our understanding of gene regulation by non-coding RNAs, including miRNAs and siRNAs. Also covered are viral RNAs, telomerase RNA, and tools for scientists who work on RNA. Each chapter is written by one or more experts in the field.

The book has just been released by Cold Spring Harbor Laboratory Press, and is essential reading for all molecular biologists and biochemists, as well as chemists interested in RNA technology, information storage, or enzyme catalysis.


'/>"/>

Contact: Ingrid Benirschke
benirsch@cshl.edu
619-275-6021
Cold Spring Harbor Laboratory
Source:Eurekalert  

Related biology news :

1. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
2. Biophysical Reviews makes debut in 2009
3. Reviews of microbial gene language published in special issue of Trends in Microbiology
4. EPA reviews Univ. of Michigan dioxin study
5. New book reviews the structure and function of cell junctions
6. New book reviews research on p53 -- the guardian of the genome -- and its relatives
7. NOAA report reviews ecosystem management in national marine sanctuaries
8. Teleconference Alert: LyondellBasell Reviews Second Quarter 2010 Financial Results
9. Modern genetics vs. ancient frog-killing fungus
10. Genetic based human diseases are an ancient evolutionary legacy
11. 6,000km trip to reveal clues to ancient migration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New book reviews ancient and modern worlds of RNA
(Date:4/13/2017)... SANTA MONICA, Calif. , April 13, 2017 /PRNewswire/ ... New York will feature emerging and ... Innovation Summits. Both Innovation Summits will run alongside the ... variety of speaker sessions, panels and demonstrations focused on ... east coast,s largest advanced design and manufacturing event will ...
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
(Date:4/11/2017)... , April 11, 2017 No two ... researchers at the New York University Tandon School ... Engineering have found that partial similarities between prints ... used in mobile phones and other electronic devices ... The vulnerability lies in the fact that ...
Breaking Biology News(10 mins):
(Date:5/18/2017)... ... May 17, 2017 , ... ... example, are more likely to develop Alzheimer’s disease, while men are at greater ... for this gender-specific neuronal bias is the aim of a research program at ...
(Date:5/16/2017)... ... May 16, 2017 , ... ... of its new ProxiMeta™ Hi-C metagenomic deconvolution service. ProxiMeta enables researchers to ... high-molecular-weight DNA extraction—speeding research insights at lower cost. , “We’re very excited ...
(Date:5/16/2017)... , May 16, 2017 Telehealth has ... organizations and something that has been kept completely ... optimization. But according to   Logicalis Healthcare Solutions ... international IT solutions and managed services provider ( ... often overlooked – interrelationship between telehealth, imaging, and ...
(Date:5/15/2017)... ... 2017 , ... Tunnell Consulting announced that Julia O’Neill, principal and ... Specifications in Process Validation,” at the Process Validation Summit 2017, May 18 and ... from the pharmaceutical and biotech industries to explore processes, strategies and new approaches to ...
Breaking Biology Technology: