Navigation Links
New book reviews ancient and modern worlds of RNA

COLD SPRING HARBOR, N.Y. (Sept. 28, 2010) -- A new book, RNA Worlds: From Life's Origins to Diversity in Gene Regulation, reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.

"[T]he plasticity of RNA stemming from its 2' hydroxyl group and single-stranded nature, which permits diverse folding in contrast to its storage molecule cousin, DNA, continues to fascinate," write the editors, John F. Atkins, Raymond F. Gesteland, and Thomas R. Cech, in the book's preface.

Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA is now known to be a highly versatile molecule that has multiple roles in cells. It can function as an enzyme, scaffold various subcellular structures, and regulate gene expression through a variety of mechanisms, as well as act as a key component of the protein synthesis and splicing machinery. Perhaps most interestingly, increasing evidence indicates that RNA preceded DNA as the hereditary material and played a crucial role in the early evolution of life on Earth.

The early chapters of the book analyze the role of RNA in the first life forms and the appearance of cells. Subsequent chapters examine riboswitches and ribozymes, establishing what the RNA molecule is capable of alone. The book goes on to discuss the evolution of ribosomes and the functions of RNPs, before reviewing the recent work that has revolutionized our understanding of gene regulation by non-coding RNAs, including miRNAs and siRNAs. Also covered are viral RNAs, telomerase RNA, and tools for scientists who work on RNA. Each chapter is written by one or more experts in the field.

The book has just been released by Cold Spring Harbor Laboratory Press, and is essential reading for all molecular biologists and biochemists, as well as chemists interested in RNA technology, information storage, or enzyme catalysis.


Contact: Ingrid Benirschke
Cold Spring Harbor Laboratory

Related biology news :

1. Sirtris review of sirtuin therapeutics for diseases of aging in Nature Reviews Drug Discovery
2. Biophysical Reviews makes debut in 2009
3. Reviews of microbial gene language published in special issue of Trends in Microbiology
4. EPA reviews Univ. of Michigan dioxin study
5. New book reviews the structure and function of cell junctions
6. New book reviews research on p53 -- the guardian of the genome -- and its relatives
7. NOAA report reviews ecosystem management in national marine sanctuaries
8. Teleconference Alert: LyondellBasell Reviews Second Quarter 2010 Financial Results
9. Modern genetics vs. ancient frog-killing fungus
10. Genetic based human diseases are an ancient evolutionary legacy
11. 6,000km trip to reveal clues to ancient migration
Post Your Comments:
Related Image:
New book reviews ancient and modern worlds of RNA
(Date:11/16/2015)... JOSE, Calif. , Nov 16, 2015 /PRNewswire/ ... developer of human interface solutions, today announced expansion ... Synaptics TouchView ™ touch controller and display ... architectural revolution of smartphones. These new TDDI products ... include TD4100 (HD resolution), TD4302 (WQHD resolution), and ...
(Date:11/12/2015)... Mass. , Nov. 12, 2015  Arxspan ... Institute of MIT and Harvard for use of ... discovery information management tools. The partnership will support ... both biological and chemical research information internally and ... will be used for managing the Institute,s electronic ...
(Date:11/11/2015)... MedNet Solutions , an innovative SaaS-based eClinical technology company that ... announce that it will be a Sponsor of the ... held November 17-19 in Hamburg , Germany.  ... iMedNet , MedNet,s easy-to-use, proven and affordable eClinical ... able to deliver time and cost savings of up to ...
Breaking Biology News(10 mins):
(Date:11/26/2015)... , England , November 26, 2015 ... Lightpoint Medical, an innovative medical device company specializing in imaging ... grant from the European Commission as part of the Horizon ... the company to carry out a large-scale clinical trial in ... -->      (Logo: , --> ...
(Date:11/25/2015)... and HOLLISTON, Mass. , Nov. 25, ... HART ), a biotechnology company developing bioengineered organ ... Jim McGorry will present at the LD Micro ... at 2:30 p.m. PT. The presentation will be webcast ... days. Management will also be available at the conference ...
(Date:11/25/2015)... , November 25, 2015 ... Research Report is a professional and in-depth study ...      (Logo: ) , ... of the industry including definitions, classifications, applications and ... provided for the international markets including development trends, ...
(Date:11/24/2015)... , Nov. 24, 2015 Halozyme Therapeutics, Inc. (NASDAQ: ... Conference in New York on Wednesday, December ... Helen Torley , president and CEO, will provide a corporate overview. ... New York at 1:00 p.m. ET/10:00 a.m. PT . ... investor relations, will provide a corporate overview. --> th ...
Breaking Biology Technology: