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New book presents methods to poke and prod individual molecules
Date:11/20/2007

lear and accessible discourse, they continue. Hopefully, this will further enhance the field.

Step-by-step protocols cover a range of methods, and are broadly divided into two categories: (1) fluorescence-based imaging methods, which include both in vivo and in vitro techniques, and (2) force-based methods, such as atomic force microscopy, optical and magnetic tweezers, and nanopores. Results from these experiments provide valuable information about the structural properties, mechanics, and sub-cellular locations of macromolecules, often with measurements at nano- and pico-unit resolution.

Single Molecule Techniques also includes substantial background information on each technique to guide researchers through each step of designing and executing experiments that yield informative results.


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Contact: Ingrid Benirschke
benirsch@cshl.edu
619-275-6021
Cold Spring Harbor Laboratory  
Source:Eurekalert

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