Navigation Links
New book on mammary gland biology, edited by Mina Bissell, Kornelia Polyak and Jeffrey Rosen
Date:10/3/2011

Studies of mammary gland biology are essential in the fight against breast cancer. Moreover, the mammary gland represents an excellent model system for investigation of physiological and pathological processes that occur throughout the body. The branching morphogenesis that occurs during puberty and the alveogenesis processes during pregnancy, for example, recapitulate steps that occur in many tissues during embryogenesis and are also relevant to tumor invasion and metastasis. Similarly, analyses of breast cancer progression and the cell types that contribute to it yield findings applicable not only to breast cancer but widely to other cancers as well.

Written and edited by experts in the field and published by Cold Spring Harbor Laboratory Press, "The Mammary Gland as an Experimental Model," reviews our understanding of mammary gland development, physiology, and tumor formation, emphasizing the value of the organ as a model system. The contributors examine the roles of hormones, growth factors, oncogenes, and the extracellular matrix in normal development and cancer. In addition, they discuss the nature of the mammary gland stem cell population and review the gene expression programs activated and chromatin modifications that occur as the different cell lineages present differentiate.

The book also contains chapters covering the many experimental approaches that have been used in this field, including transplantation, genetic engineering, RNA interference and genomics, three dimensional culture models, and live cell imaging. It will thus be of interest to all researchers working in cell, developmental, and cancer biology, as well as those focused specifically on mammary gland biology and breast cancer.


'/>"/>
Contact: Elizabeth Powers
powerse@cshl.edu
516-422-4101
Cold Spring Harbor Laboratory
Source:Eurekalert  

Page: 1

Related biology news :

1. New book on mammary gland biology from Cold Spring Harbor Laboratory Press
2. Study: Illegal fishing harming present and future New England groundfish fisheries
3. Data published in the New England Journal of Medicine support use of raxibacumab (ABthrax) for the treatment of inhalation anthrax
4. Stem cell success points to way to regenerate parathyroid glands
5. LSUHSCs England plays key role in developing new ALS treatment guidelines
6. Researchers issue outlook for a significant New England red tide in 2010
7. Researchers discover potential solutions to New England roadside erosion
8. SomaLogic and New England Biolabs announce agreement to use SOMAmers for multiple PCR products
9. Are New Englands iconic maples at risk?
10. Key to future medical breakthroughs is systems biology, say leading European scientists
11. Darwins seminal impact on biology, anthropology, philosophy and psychology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New book on mammary gland biology, edited by Mina Bissell, Kornelia Polyak and Jeffrey Rosen
(Date:6/22/2016)... 22, 2016   Acuant , the ... solutions, has partnered with RightCrowd ® ... Visitor Management, Self-Service Kiosks and Continuous Workforce ... add functional enhancements to existing physical access ... venues with an automated ID verification and ...
(Date:6/21/2016)... , June 21, 2016 NuData Security announced ... new role of principal product architect and that ... director of customer development. Both will report directly ... officer. The moves reflect NuData,s strategic growth in ... to high customer demand and customer focus values. ...
(Date:6/16/2016)... , June 16, 2016 ... size is expected to reach USD 1.83 billion ... Grand View Research, Inc. Technological proliferation and increasing ... applications are expected to drive the market growth. ... , The development of advanced multimodal ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... release of its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering ... retention in this eBook by providing practical tips, tools, and strategies for clinical ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... and Mold) microbial test has received AOAC Research Institute approval 061601. , “This ... introduced last year,” stated Bob Salter, Vice President of Regulatory and Industrial Affairs. ...
Breaking Biology Technology: