Navigation Links
New book on endocytosis from Cold Spring Harbor Laboratory Press
Date:3/7/2014

During endocytosis, extracellular molecules and plasma membrane components are selectively internalized by cells. This fundamental process of "cellular ingestion" is required for diverse activities such as nutrient uptake, cell adhesion and migration, signal transduction, cytokinesis, neurotransmission, and antigen presentation. Pathogens (e.g., HIV) exploit endocytic pathways to gain entry into cells, and defects in the endocytic machinery can lead to diseases such as cancer.

Written and edited by experts in the field, Endocytosis covers all of the major pathways of endocytosis and postendocytic trafficking and how they regulate cellular and organismal physiology. Contributors describe how cargo enters the cell via clathrin-mediated and clathrin-independent pathways, including caveolar endocytosis, micropinocytosis, cholesterol-sensitive endocytosis, phagocytosis, and the CLIC/GEEC pathway. They review the numerous machineries (e.g., Rab GTPases, tethering factors, and retromer) that transport cargo through endosomes and deliver it to lysosomes or recycle it back to the cell surface, and the signals and mechanisms governing these sorting decisions. Topics such as lysosomal dynamics, the biophysical challenges of bending membranes, and the evolution of endocytic systems are also covered.

This volume also includes substantial discussion of the roles of endocytic trafficking in organismal development, physiology, and disease. It is thus an indispensable reference for cell biologists, but also for neuroscientists, immunologists, developmental biologists, microbiologists, and others concerned with the physiological and therapeutic implications of this key cellular process.


'/>"/>

Contact: Robert Redmond
rredmond@cshl.edu
516-422-4101
Cold Spring Harbor Laboratory
Source:Eurekalert  

Page: 1

Related biology news :

1. Mid-Atlantic suburbs can expect an early spring thanks to the heat of the big city
2. Annual Drug Discovery Conferences Being Held in Boston MA, Spring 2012
3. An early spring drives butterfly population declines
4. Why spring is blooming marvelous (and climate change makes it earlier)
5. First fruitful, then futile: Ammonites or the boon and bane of many offspring
6. Springer and the Beijing Normal University Press sign agreement on new book series
7. Springer will collaborate with the Italian Society for Ultrasound in Medicine and Biology
8. Genetics Society of America announces Spring 2013 DeLill Nasser Travel Award recipients
9. Fetal exposure to PVC plastic chemical linked to obesity in offspring
10. In the Eastern US, spring flowers keep pace with warming climate
11. An early sign of spring, earlier than ever
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New book on endocytosis from Cold Spring Harbor Laboratory Press
(Date:6/21/2016)... , June 21, 2016 NuData Security announced ... new role of principal product architect and that ... director of customer development. Both will report directly ... officer. The moves reflect NuData,s strategic growth in ... to high customer demand and customer focus values. ...
(Date:6/9/2016)... June 9, 2016 Paris ... Teleste,s video security solution to ensure the safety of people ... during the major tournament Teleste, an international ... and services, announced today that its video security solution will ... to back up public safety across the country. The system ...
(Date:6/2/2016)... -- Perimeter Surveillance & Detection Systems, Biometrics ... Support & Other Service  The latest report ... analysis of the global Border Security market . ... $17.98 billion in 2016. Now: In November ... software and hardware technologies for advanced video surveillance. ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... June 23, 2016  The Prostate Cancer Foundation (PCF) is pleased ... and faster cures for prostate cancer. Members of the Class of 2016 were ... Read More About the Class of 2016 PCF Young ... ... ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, ... of the Supplyframe Design Lab . Located in Pasadena, Calif., the Design ... of how hardware projects are designed, built and brought to market. , The ...
(Date:6/23/2016)... 2016 Apellis Pharmaceuticals, Inc. today announced ... of its complement C3 inhibitor, APL-2. The trials ... dose studies designed to assess the safety, tolerability, ... in healthy adult volunteers. Forty subjects ... single dose (ranging from 45 to 1,440mg) or ...
(Date:6/23/2016)... YORK , June 23, 2016 ... trading session at 4,833.32, down 0.22%; the Dow Jones Industrial ... S&P 500 closed at 2,085.45, down 0.17%. Stock-Callers.com has initiated ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ), ... Therapeutics Inc. (NASDAQ: BIND ). Learn more about ...
Breaking Biology Technology: