Navigation Links
New biological route for swine flu to human infections
Date:12/10/2009

ation of the avian virus became enhanced in humans.

"The SR polymorphism mutation in PB2 accomplishes the same goal as the change from glutamic acid to lysine," Mehle explains. "The fact that all of the 2009 H1N1 isolates contain this second mutation supports the notion that it is important for transmission into humans, although we don't yet know the relative importance of the changes in the polymerase versus mutations elsewhere in the virus."

Mehle and Doudna are now conducting a series of biochemical and structural studies to get a comprehensive understanding of this polymerase mutation and why it evolved. Such studies are necessary before effective new antivirals can be developed.

"We need to identify what is unique about human cells that requires mutations in the influenza polymerase, possibly providing new avenues to exploit in developing therapeutic strategies," Mehle says.


'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers discover biological basis of bacterial immune system
2. Dr. William Brody, President of the Salk Institute for Biological Studies, Appointed to GenVaults Board of Directors
3. Synthetic cells shed biological insights while delivering battery power
4. Study explores how life experiences contribute to the biological changes of Alzheimers
5. Securing biological select agents and toxins will require developing a culture of trust
6. Individual cells isolated from biological clock can keep daily time, but are unreliable
7. Evolution of the appendix: A biological remnant no more
8. Biological clocks of insects could lead to more effective pest control
9. Microfluidic palette may paint clearer picture of biological processes
10. Iron and biological production in the high-latitude North Atlantic
11. Biological warfare in bacteria offers hope for new antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New biological route for swine flu to human infections
(Date:7/2/2015)... 2015 Fingerprint Cards has received an ... FPC1155 from the distributor World Peace Industrial Group (WPI), part ... Asia . Deliveries are planned to take ... used by smartphone manufacturers in Asia . ... communicated revenue guidance of approximately 2,200 MSEK for 2015. ...
(Date:6/26/2015)... 26, 2015 ATL Technology, LLC, a top provider ... in single use solutions, headquartered in Springville, Utah ... California corporation with locations in ... Jose, Costa Rica ). This acquisition will ... with ATL Technology,s existing facility in Costa ...
(Date:6/24/2015)... , June 24, 2015 The biologics ... The major drivers for the market include growth of ... of new drug launches. Over the years, the number ... Between 2001 and 2010, the FDA approved 225 drug ... to WIPO, Europe accounted for ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4
... premature fusion of the skull, is estimated to affect one ... physicians have used two procedures to correct the problems. One ... strip back the scalp of the infant and reshape the ... procedure required a small incision near the point of the ...
... hard to study a creature when you only catch ... one of the big stumbling blocks for marine biologists ... allowed them to peer farther across, and deeper under, ... Satellite tracking systems and acoustic sensors are giving researchers ...
... worlds sharks are disappearing. These fearsome yet charismatic fish ... now at risk of extinction as a result. New ... overfishing, and other work shows that the deeper sharks ... recover. Yet researchers are just now learning critical details ...
Cached Biology News:Craniosynostosis minimally invasive surgery holds more promise than old procedure 2Unveiling the underwater ways of the white shark 2Unveiling the underwater ways of the white shark 3New research reveals shark superhighways and hotspots 2New research reveals shark superhighways and hotspots 3New research reveals shark superhighways and hotspots 4
(Date:7/27/2015)... CHICAGO and FRANKLIN, Tenn. ... Inc. ("Capella"), a privately-owned  premier provider of health care ... companies in the U.S., today announced that its ... has signed a definitive agreement with Medical Properties ... the acquisition of Capella for $900 million in cash.  The ...
(Date:7/27/2015)... ... 27, 2015 , ... This is a professional and in-depth ... overview of the industry including definitions, classifications, applications and industry chain structure. The ... landscape analysis, and key regions development status. Development policies and plans are discussed ...
(Date:7/27/2015)... Wis. (PRWEB) , ... July 27, 2015 , ... ... and facility identification solutions, today announced a new video: 3 Ways to ... OSHA’s Hazard Communication Standard and the Globally Harmonized System (GHS) by effectively labeling ...
(Date:7/27/2015)... Research presented at the 2015 AACC Annual ... studies that led to a fingerprick Ebola test becoming ... to receive approval from the World Health Organization (WHO). ... on West Africa by identifying ... to isolate and treat these patients much faster than ...
Breaking Biology Technology:Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 2Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 3Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 4Capella Healthcare Announces Agreement With Medical Properties Trust, Inc. 52015 Biophotonics Market Global Research 22015 Biophotonics Market Global Research 3Brady Releases “3 Roads to GHS Labels” Video 2Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak 2Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak 3
... intense scrutiny that started in September when Vioxxs manufacturer ... concerns, the U.S. Food and Drug Administration and the ... the biggest challenges has been the pipeline problem, the ... innovative medical therapies reaching patients. In its March ...
... Much of Thursday's Digital Healthcare Conference in ... of them. , ,In today's issue, the first of ... Digital Healthcare Conference, you'll read about the technology choices ... those choices. Next issue, look for coverage of the ...
... While Wisconsin may be ahead of the ... way to go before full use of electronic health ... the recognized quality improvements and long-term cost savings, implementation ... the Internet Business Solutions Group Healthcare Practice ...
Cached Biology Technology:Challenging times for FDA and drug companies equals IT opportunities 2Challenging times for FDA and drug companies equals IT opportunities 3The tough choices facing health care 2The tough choices facing health care 3Organizations finding ways to overcome barriers to electronic health records implementation 2Organizations finding ways to overcome barriers to electronic health records implementation 3Organizations finding ways to overcome barriers to electronic health records implementation 4
Peptide-affinity Purified Polyclonal Antibody to MTR...
Polyclonal Antibody to AGAP1 / Centaurin, gamma 2...
Polyclonal Antibody to PRG3...
IRF7 Immunogen: Synthetic peptide corresponding to residues E(463) G T Q R E G V S S L D S S S(477) of human IRF7. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: