Navigation Links
New biological route for swine flu to human infections
Date:12/10/2009

ation of the avian virus became enhanced in humans.

"The SR polymorphism mutation in PB2 accomplishes the same goal as the change from glutamic acid to lysine," Mehle explains. "The fact that all of the 2009 H1N1 isolates contain this second mutation supports the notion that it is important for transmission into humans, although we don't yet know the relative importance of the changes in the polymerase versus mutations elsewhere in the virus."

Mehle and Doudna are now conducting a series of biochemical and structural studies to get a comprehensive understanding of this polymerase mutation and why it evolved. Such studies are necessary before effective new antivirals can be developed.

"We need to identify what is unique about human cells that requires mutations in the influenza polymerase, possibly providing new avenues to exploit in developing therapeutic strategies," Mehle says.


'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Researchers discover biological basis of bacterial immune system
2. Dr. William Brody, President of the Salk Institute for Biological Studies, Appointed to GenVaults Board of Directors
3. Synthetic cells shed biological insights while delivering battery power
4. Study explores how life experiences contribute to the biological changes of Alzheimers
5. Securing biological select agents and toxins will require developing a culture of trust
6. Individual cells isolated from biological clock can keep daily time, but are unreliable
7. Evolution of the appendix: A biological remnant no more
8. Biological clocks of insects could lead to more effective pest control
9. Microfluidic palette may paint clearer picture of biological processes
10. Iron and biological production in the high-latitude North Atlantic
11. Biological warfare in bacteria offers hope for new antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New biological route for swine flu to human infections
(Date:4/23/2014)... newly coined term for novels and films which focus on ... Copenhagen shows how these fictions serve as a mental laboratory ... change and imagine other living conditions. , "Global warming ... atmosphere; it is also a cultural phenomenon in which meaning ... films we see. And there are so many of them ...
(Date:4/23/2014)... HOUSTON, April 23, 2014 A biomedical engineer at ... highly innovative technology to make blood transfusions safer. His ... the National Institutes of Health (NIH). , Blood ... one of modern medicine,s absolute necessities. Without them, for ... mean transfusions are perfect, however. There,s strong evidence that ...
(Date:4/22/2014)... to behave at the dinner tablecut up their food and ... Eating Behaviors , found that when 6-10 year old children ... such as drumsticks, whole apples, or corn on the cob ... cut. "They were twice as likely to disobey adults ... Professor and Director of the Cornell Food and Brand Lab. ...
Breaking Biology News(10 mins):Fiction prepares us for a world changed by global warming 2Fiction prepares us for a world changed by global warming 3UH biomedical engineer works to make blood transfusions safer 2UH biomedical engineer works to make blood transfusions safer 3Biting vs. chewing 2
... have determined that most types of melanoma cells can ... form of skin cancer does not conform to the ... the researchers found that melanoma tumor cells can change ... making the malignant cells a stealthy, shape-shifting target for ...
... of California, San Diego NanoEngineers won a grant from ... tools to manufacture biodegradable frames around which heart tissues ... methods for growing tissues that mimic nature,s fine-grained details, ... grow replacement cardiac tissues for people who have suffered ...
... Elsevier, the leading publisher of scientific, technical and ... eBook collections available for advance purchase and to be ... The 2011 offerings total 439 titles spread across 24 ... between January 1 and December 31, 2011. ...
Cached Biology News:More evidence that melanoma does not conform to the cancer stem cell model 2More evidence that melanoma does not conform to the cancer stem cell model 3Nanoengineers aim to grow tissues with functional blood vessels 2Nanoengineers aim to grow tissues with functional blood vessels 3Elsevier announces the SciVerse ScienceDirect eBooks collection 2011 frontlist 2
(Date:1/14/2014)... Boston, MA (PRWEB) January 14, 2014 iLab ... Michelle Detwiler as the new Director of Product Strategy. In ... as well as iLab sub-teams to guide in the development ... that iLab provides the maximum possible benefit to the scientific ...
(Date:1/14/2014)... January 14, 2014 Global Record ... innovative information technology solutions for patients, physicians, the ... stakeholders, announced today the signing of a three-year ... and Drug Administration (FDA). This initiative is ...
(Date:1/14/2014)... Kerr Corporation, a leading manufacturer of innovative dental ... about dual arch impressions on its dental blog. ... blog entry serves up a list of tips to help ... by Dr. David Little as he crafts a porcelain crown ...
(Date:1/14/2014)... BioMedomics, Inc. , a Point of Care ... novel disease specific POC tests, announced today that it has ... of $690,000. The investment is from private investors and is ... of private investors has significant successful experience in early investments ...
Breaking Biology Technology:iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2BioMedomics, Inc. Closes $690K Round of Financing 2
... 13 Accuri Cytometers, Inc. today announced the completion ... financing included current investors Fidelity Biosciences, Flagship Ventures, Baird ... InvestMichigan! Program co-managed by Credit Suisse. Accuri will ... provide additional working and growth capital to support the ...
... University a network of tiny sensors as small as ... determined intruder. Scattered outdoors on rocks, fence posts and ... dewdrops are a completely new and cost-effective system for safeguarding ... and his Tel Aviv University Faculty of Engineering team drew ...
... SAN DIEGO, July 10 David Koos, Chairman and CEO ... BMSN), today said that he believes that stem cell cord ... The Bio-Matrix CEO stated that hospitals throughout the world ... banks. "Hospitals from the U.S. to India are naturally ...
Cached Biology Technology:Accuri Cytometers Completes $4 Million Series D Financing 2Accuri Cytometers Completes $4 Million Series D Financing 3Accuri Cytometers Completes $4 Million Series D Financing 4Accuri Cytometers Completes $4 Million Series D Financing 5Intruder alert: Tel Aviv University's 'Smart Dew' will find you! 2Stem Cell Cord Blood 'Banking' Is Huge Global Business for Hospitals, Says CEO of Bio-Matrix Scientific Group Inc. 2
... adapter allows the Thermo-Fast® ... AB-1000) PCR plates to ... ABI PRISM® 3700 capillary ... for information on the ...
Spectrolyse (pL) PAI kit is a two-stage indirect enzymatic assay for the quantitative determination of Plasminogen Activator Inhibitor (PAI-1) activity in plasma. Sample Type: plasma...
Rabbit anti-CRSP1 (TRAP220), Polyclonal Antibody, Unconjugated Applications: Immunohistochemistry - 1:100 - 1:500...
... White lyophilized solid. PROTECT FROM LIGHT. PACKAGED ... of γ-secretase. Equipotently inhibits the release of ... 2.6 μM) and Aβ x-42 (ED ... cells stably transfected with the Amyloid Precursor ...
Biology Products: